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AT1G42560.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data
Description (TAIR10) protein_coding : Seven transmembrane MLO family protein
Curator
Summary (TAIR10)
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO9 belongs to the clade III, with AtMLO5, AtMLO7, AtMLO8, and AtMLO10. The gene is expressed during early seedling growth, in cotyledon vascular system, in flowers (with strong expression in anthers) in siliques and fruit abscission zone; not expressed in roots, or in mature rosette leaves, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
Computational
Description (TAIR10)
MILDEW RESISTANCE LOCUS O 9 (MLO9); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT2G33670.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:26089eggNOG:ENOG410IJ4AeggNOG:ENOG410YDNXEMBL:AC025815
EMBL:AC035249EMBL:AF369570EMBL:CP002684EnsemblPlants:AT1G42560
EnsemblPlants:AT1G42560.1entrez:840861GeneID:840861Genevisible:Q94KB4
GO:GO:0005886GO:GO:0006952GO:GO:0009607GO:GO:0016021
Gramene:AT1G42560.1hmmpanther:PTHR31942hmmpanther:PTHR31942:SF8HOGENOM:HOG000239166
InParanoid:Q94KB4InterPro:IPR004326KEGG:ath:AT1G42560KO:K08472
OMA:YIASICVPaxDb:Q94KB4Pfam:PF03094Pfam:Q94KB4
PhylomeDB:Q94KB4PIR:E96495PRIDE:Q94KB4PRO:PR:Q94KB4
Proteomes:UP000006548RefSeq:NP_174980.3STRING:3702.AT1G42560.1TAIR:AT1G42560
tair10-symbols:ATMLO9tair10-symbols:MLO9TMHMM:TMhelixUniGene:At.28693
UniProt:Q94KB4
Coordinates (TAIR10) chr1:-:15980209..15983328
Molecular Weight (calculated) 53212.70 Da
IEP (calculated) 9.54
GRAVY (calculated) 0.16
Length 460 amino acids
Sequence (TAIR10)
(BLAST)
001: MAGGGGGGGG EGPRQLDQTP TWAVSTVCGV IILISIILEL IIHKVGEVFE RKKKKALFEA LEKIKNELMV LGFISLLLTF GQNYIASICV PSRYGHAMSF
101: CGPYDGPSED DRKKLKKTDH AMRILYSVQR RSLADAPPVN CKKDYVALIS LNALHQVHIF IFFLAVFHVI YSAITMMLGR AKIRGWKVWE QEVIHEQEMM
201: NDPSRFRLTH ETSFVREHVN SWASNKFFFY VMCFFRQILR SVRKSDYLTM RHGFISVHLA PGMKFDFQKY IKRSLEDDFK VVVGIRPELW AFVMLFLLFD
301: VHGWYVTAVI TMIPPLLTLA IGTKLQAIIS YMALEIQERH AVIQGMPVVN VSDQHFWFEK PDLVLHMIHF VLFQNAFEIT YFFWIWYEFG LRSCFHHHFG
401: LIIIRVCLGV GVQFLCSYIT LPLYALVTQM GSTMKRSVFD EQTSKALEQW HKKARKKNEK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)