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AT4G02600.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Seven transmembrane MLO family protein
Curator
Summary (TAIR10)
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO1 belongs to the clade II, with ATMLO13 and ATMLO15. The gene is expressed during early seedling growth, in root and cotyledon vascular system, in pollen and in papillae, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
Computational
Description (TAIR10)
MLO1; FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT2G44110.1); Has 552 Blast hits to 532 proteins in 57 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 548; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink).
Protein Annotations
BioGrid:13518eggNOG:ENOG410IGD7eggNOG:ENOG410ZUVBEMBL:AC002330EMBL:AL161494EMBL:AY072135EMBL:AY113992
EMBL:CP002687EMBL:Z95352EnsemblPlants:AT4G02600EnsemblPlants:AT4G02600.1EnsemblPlants:AT4G02600.2entrez:828229GeneID:828229
Genevisible:O49621GO:GO:0005886GO:GO:0006952GO:GO:0009607GO:GO:0016021Gramene:AT4G02600.1Gramene:AT4G02600.2
hmmpanther:PTHR31942hmmpanther:PTHR31942:SF26HOGENOM:HOG000239166InParanoid:O49621InterPro:IPR004326iPTMnet:O49621KEGG:ath:AT4G02600
KO:K08472OMA:KHQKALFPaxDb:O49621Pfam:O49621Pfam:PF03094PhylomeDB:O49621PIR:T01089
PRIDE:O49621PRO:PR:O49621Proteomes:UP000006548RefSeq:NP_001031578.1RefSeq:NP_192169.1STRING:3702.AT4G02600.1TAIR:AT4G02600
tair10-symbols:ATMLO1tair10-symbols:MLO1TMHMM:TMhelixUniGene:At.20439UniProt:O49621
Coordinates (TAIR10) chr4:+:1144141..1147156
Molecular Weight (calculated) 59129.20 Da
IEP (calculated) 8.69
GRAVY (calculated) 0.19
Length 526 amino acids
Sequence (TAIR10)
(BLAST)
001: MGHGGEGMSL EFTPTWVVAG VCTVIVAISL AVERLLHYFG TVLKKKKQKP LYEALQKVKE ELMLLGFISL LLTVFQGLIS KFCVKENVLM HMLPCSLDSR
101: REAGASEHKN VTAKEHFQTF LPIVGTTRRL LAEHAAVQVG YCSEKGKVPL LSLEALHHLH IFIFVLAISH VTFCVLTVIF GSTRIHQWKK WEDSIADEKF
201: DPETALRKRR VTHVHNHAFI KEHFLGIGKD SVILGWTQSF LKQFYDSVTK SDYVTLRLGF IMTHCKGNPK LNFHKYMMRA LEDDFKQVVG ISWYLWIFVV
301: IFLLLNVNGW HTYFWIAFIP FALLLAVGTK LEHVIAQLAH EVAEKHVAIE GDLVVKPSDE HFWFSKPQIV LYLIHFILFQ NAFEIAFFFW IWVTYGFDSC
401: IMGQVRYIVP RLVIGVFIQV LCSYSTLPLY AIVSQMGSSF KKAIFEENVQ VGLVGWAQKV KQKRDLKAAA SNGDEGSSQA GPGPDSGSGS APAAGPGAGF
501: AGIQLSRVTR NNAGDTNNEI TPDHNN
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)