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AT5G12250.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:28611809 (2017): cytosol
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:22215637 (2012): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:17317660 (2007): plasma membrane
  • PMID:15574830 (2004): plasma membrane
  • PMID:14505352 (2003): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : beta-6 tubulin
Curator
Summary (TAIR10)
Encodes a beta-tubulin. Expression of TUB6 has been shown to decrease in response to cold treatment.
Computational
Description (TAIR10)
beta-6 tubulin (TUB6); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: microtubule-based process, response to salt stress, response to cold; LOCATED IN: microtubule cytoskeleton, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Beta tubulin (InterPro:IPR002453), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Beta tubulin, autoregulation binding site (InterPro:IPR013838), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: tubulin beta chain 3 (TAIR:AT5G62700.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioGrid:16378ChEMBL:CHEMBL2424501eggNOG:COG5023eggNOG:KOG1375EMBL:AB007727EMBL:AF360260EMBL:AY040074
EMBL:CP002688EMBL:M84703EnsemblPlants:AT5G12250EnsemblPlants:AT5G12250.1entrez:831100Gene3D:1.10.287.600Gene3D:3.30.1330.20
Gene3D:3.40.50.1440GeneID:831100Genevisible:P29514GO:GO:0003924GO:GO:0005200GO:GO:0005525GO:GO:0005737
GO:GO:0005874GO:GO:0005886GO:GO:0007017GO:GO:0009409GO:GO:0009651GO:GO:0015630Gramene:AT5G12250.1
hmmpanther:PTHR11588hmmpanther:PTHR11588:SF106HOGENOM:HOG000165710InParanoid:P29514InterPro:IPR000217InterPro:IPR002453InterPro:IPR003008
InterPro:IPR008280InterPro:IPR013838InterPro:IPR017975InterPro:IPR018316InterPro:IPR023123iPTMnet:P29514KEGG:ath:AT5G12250
KO:K07375ncoils:CoilOMA:LERINXQPANTHER:PTHR11588PaxDb:P29514Pfam:P29514Pfam:PF00091
Pfam:PF03953PhylomeDB:P29514PIR:JQ1590PRIDE:P29514PRINTS:PR01161PRINTS:PR01163PRO:PR:P29514
PROSITE:PS00227PROSITE:PS00228ProteinModelPortal:P29514Proteomes:UP000006548RefSeq:NP_196786.1scanprosite:PS00227scanprosite:PS00228
SMART:SM00864SMART:SM00865SMR:P29514STRING:3702.AT5G12250.1SUPFAM:SSF52490SUPFAM:SSF55307TAIR:AT5G12250
tair10-symbols:TUB6UniGene:At.23425UniGene:At.72672UniGene:At.74848UniProt:P29514
Coordinates (TAIR10) chr5:-:3961317..3962971
Molecular Weight (calculated) 50588.70 Da
IEP (calculated) 4.44
GRAVY (calculated) -0.38
Length 449 amino acids
Sequence (TAIR10)
(BLAST)
001: MREILHIQGG QCGNQIGSKF WEVVCDEHGI DPTGRYVGNS DLQLERVNVY YNEASCGRYV PRAILMDLEP GTMDSVRTGP YGQIFRPDNF VFGQSGAGNN
101: WAKGHYTEGA ELIDAVLDVV RKEAENCDCL QGFQVCHSLG GGTGSGMGTL LISKIREEYP DRMMLTFSVF PSPKVSDTVV EPYNATLSVH QLVENADECM
201: VLDNEALYDI CFRTLKLTTP SFGDLNHLIS ATMSGVTCCL RFPGQLNSDL RKLAVNLIPF PRLHFFMVGF APLTSRGSQQ YRALTVPELT QQMWDSKNMM
301: CAADPRHGRY LTASAMFRGK MSTKEVDEQM INVQNKNSSY FVEWIPNNVK SSVCDIAPRG LSMASTFIGN STSIQEMFRR VSEQFTAMFR RKAFLHWYTG
401: EGMDEMEFTE AESNMNDLVS EYQQYQDATA DDEGEYEEDE DEEEILDHE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)