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AT3G21220.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
golgi 0.959
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : MAP kinase kinase 5
Curator
Summary (TAIR10)
Encodes a mitogen-activated kinase kinase, dual specific protein kinase that is expressed in vegetative tissues and floral buds. Involved in innate immunity. This protein activates MPK3/MPK6 and early-defense genes redundantly with MKK4.In plants with both MKK5 and MKK6 levels reduced by RNAi plants, floral organs do not abscise suggestion a role for both proteins in mediating floral organ abscission.
Computational
Description (TAIR10)
MAP kinase kinase 5 (MKK5); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase kinase 4 (TAIR:AT1G51660.1); Has 130143 Blast hits to 128581 proteins in 4761 species: Archae - 120; Bacteria - 15121; Metazoa - 48301; Fungi - 12721; Plants - 32333; Viruses - 542; Other Eukaryotes - 21005 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G21220-MONOMERBioGrid:7008EC:2.7.12.2eggNOG:ENOG410XQ5AeggNOG:KOG0581EMBL:AB015316EMBL:AB023045
EMBL:AY081272EMBL:AY114558EMBL:CP002686EMBL:Y07694EnsemblPlants:AT3G21220EnsemblPlants:AT3G21220.1entrez:821676
GeneID:821676Genevisible:Q8RXG3GO:GO:0004674GO:GO:0005524GO:GO:0005737GO:GO:0007346GO:GO:0009626
GO:GO:0009814GO:GO:0010227GO:GO:0010229GO:GO:0010365GO:GO:0023014GO:GO:0031098GO:GO:0032147
Gramene:AT3G21220.1hmmpanther:PTHR24361hmmpanther:PTHR24361:SF319HOGENOM:HOG000234206InParanoid:Q8RXG3IntAct:Q8RXG3InterPro:IPR000719
InterPro:IPR008271InterPro:IPR011009InterPro:IPR017441iPTMnet:Q8RXG3KEGG:ath:AT3G21220KO:K13413OMA:CHDMYER
PaxDb:Q8RXG3Pfam:PF00069Pfam:Q8RXG3Pfscan:PS50011PhylomeDB:Q8RXG3PIR:T51340PIR:T52635
PRIDE:Q8RXG3PRO:PR:Q8RXG3PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011ProteinModelPortal:Q8RXG3Proteomes:UP000006548
Reactome:R-ATH-110056Reactome:R-ATH-112411Reactome:R-ATH-2559580Reactome:R-ATH-445144Reactome:R-ATH-450302Reactome:R-ATH-450321Reactome:R-ATH-5674135
Reactome:R-ATH-5674499RefSeq:NP_188759.1scanprosite:PS00107scanprosite:PS00108SMART:SM00220SMR:Q8RXG3STRING:3702.AT3G21220.1
SUPFAM:SSF56112TAIR:AT3G21220tair10-symbols:ATMAP2K_ALPHAtair10-symbols:ATMEK5tair10-symbols:ATMKK5tair10-symbols:MAP2K_Atair10-symbols:MEK5
tair10-symbols:MKK5UniGene:At.24898UniGene:At.71795UniProt:Q8RXG3
Coordinates (TAIR10) chr3:+:7445917..7446963
Molecular Weight (calculated) 38331.10 Da
IEP (calculated) 8.86
GRAVY (calculated) -0.25
Length 348 amino acids
Sequence (TAIR10)
(BLAST)
001: MKPIQSPSGV ASPMKNRLRK RPDLSLPLPH RDVALAVPLP LPPPSSSSSA PASSSAISTN ISAAKSLSEL ERVNRIGSGA GGTVYKVIHT PTSRPFALKV
101: IYGNHEDTVR RQICREIEIL RSVDHPNVVK CHDMFDHNGE IQVLLEFMDQ GSLEGAHIWQ EQELADLSRQ ILSGLAYLHR RHIVHRDIKP SNLLINSAKN
201: VKIADFGVSR ILAQTMDPCN SSVGTIAYMS PERINTDLNH GRYDGYAGDV WSLGVSILEF YLGRFPFAVS RQGDWASLMC AICMSQPPEA PATASQEFRH
301: FVSCCLQSDP PKRWSAQQLL QHPFILKATG GPNLRQMLPP PRPLPSAS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)