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AT3G12360.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : Ankyrin repeat family protein
Curator
Summary (TAIR10)
Encodes a protein with an ankyrin motif and transmembrane domains that is involved in salt tolerance. Expressed throughout the plant and localized to the plasma membrane. Loss of function mutations show an increased tolerance to salt based on assaying seedling growth in the presence of salt. In the mutants, induction of genes required for production of reactive oxygen species is reduced suggesting that itn1 promotes ROS production.
Computational
Description (TAIR10)
INCREASED TOLERANCE TO NACL (ITN1); INVOLVED IN: response to salt stress; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ankyrin repeat-containing domain (InterPro:IPR020683), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: Ankyrin repeat family protein (TAIR:AT3G09550.1); Has 61607 Blast hits to 26705 proteins in 1191 species: Archae - 49; Bacteria - 5778; Metazoa - 28187; Fungi - 6605; Plants - 4929; Viruses - 594; Other Eukaryotes - 15465 (source: NCBI BLink).
Protein Annotations
BioGrid:5748eggNOG:COG0666eggNOG:KOG0504EMBL:AC069474
EMBL:AP002047EMBL:AY085485EMBL:CP002686EnsemblPlants:AT3G12360
EnsemblPlants:AT3G12360.1entrez:820414Gene3D:1.25.40.20GeneID:820414
Genevisible:Q9C7A2GO:GO:0005634GO:GO:0005886GO:GO:0009651
GO:GO:0016021GO:GO:0034613Gramene:AT3G12360.1hmmpanther:PTHR24177
hmmpanther:PTHR24177:SF10HOGENOM:HOG000234376InParanoid:Q9C7A2InterPro:IPR002110
InterPro:IPR020683InterPro:IPR026961KEGG:ath:AT3G12360OMA:MEKGGMI
PaxDb:Q9C7A2Pfam:PF00023Pfam:PF12796Pfam:PF13637
Pfam:PF13962Pfam:Q9C7A2Pfscan:PS50088Pfscan:PS50297
PhylomeDB:Q9C7A2PRIDE:Q9C7A2PRO:PR:Q9C7A2PROSITE:PS50088
PROSITE:PS50297ProteinModelPortal:Q9C7A2Proteomes:UP000006548RefSeq:NP_187842.1
SMART:SM00248SMR:Q9C7A2STRING:3702.AT3G12360.1SUPFAM:SSF48403
TAIR:AT3G12360tair10-symbols:ITN1TMHMM:TMhelixUniGene:At.39610
UniProt:Q9C7A2
Coordinates (TAIR10) chr3:+:3934146..3936495
Molecular Weight (calculated) 64139.10 Da
IEP (calculated) 9.60
GRAVY (calculated) -0.17
Length 590 amino acids
Sequence (TAIR10)
(BLAST)
001: MAASSYVDGE RDMEKGGMIL LQSSENQNPM IDPSPTPSPS ATATAPALVL SNSGKRMDQA GKKKYVKQVT GRHNDTELHL AAQRGDLAAV QQILKDINSQ
101: MEGILSGEEF DAEVAEIRAS IVNEVNELGE TALFTAADKG HLDVVKELLK YSSRESIAKK NRSGYDPLHI AAIQGHHAIV EVLLDHDATL SQTFGPSNAT
201: PLVSAAMRGH TEVVNQLLSK AGNLLEISRS NNKNALHLAA RQGHVEVIKA LLSKDPQLAR RIDKKGQTAL HMAVKGQSSE VVKLLLDADP AIVMQPDKSC
301: NTALHVATRK KRAEIVELLL SLPDTNANTL TRDHKTALDI AEGLPLSEES SYIKECLARS GALRANELNQ PRDELRSTVT QIKNDVHIQL EQTKRTNKNV
401: HNISKELRKL HREGINNATN SVTVVAVLFA TVAFAAIFTV PGGDNNDGSA VVVGRASFKI FFIFNALALF TSLAVVVVQI TLVRGETKAE KRVVEVINKL
501: MWLASMCTSV AFLASSYIVV GRKNEWAAEL VTVVGGVIMA GVLGTMTYYV VKSKRTRSMR KKVKSARRSG SNSWHHSDFS NSEVDPIFAI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)