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AT5G65970.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Seven transmembrane MLO family protein
Curator
Summary (TAIR10)
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO10 belongs to the clade III, with AtMLO5, AtMLO7, AtMLO8, and AtMLO9. The gene is expressed in root and cotyledon vascular system, in root-shoot junction and lateral root primordia and in developing siliques, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s
Computational
Description (TAIR10)
MILDEW RESISTANCE LOCUS O 10 (MLO10); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: seedling growth, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT2G17430.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioGrid:21969EMBL:BT033095EnsemblPlants:AT5G65970EnsemblPlants:AT5G65970.1
entrez:836727ExpressionAtlas:B3LFA7GeneID:836727GO:GO:0006952
GO:GO:0009607GO:GO:0016021Gramene:AT5G65970.1hmmpanther:PTHR31942
hmmpanther:PTHR31942:SF18InterPro:IPR004326KEGG:ath:AT5G65970KO:K08472
ncoils:CoilOMA:WHERRILPaxDb:B3LFA7PaxDb:Q9FKY5
Pfam:PF03094Pfam:Q9FKY5PhylomeDB:B3LFA7PRIDE:B3LFA7
Proteomes:UP000006548RefSeq:NP_201398.1STRING:3702.AT5G65970.1TAIR:AT5G65970
tair10-symbols:ATMLO10tair10-symbols:MLO10TMHMM:TMhelixUniGene:At.9206
UniProt:B3LFA7UniProt:Q9FKY5
Coordinates (TAIR10) chr5:-:26387509..26390407
Molecular Weight (calculated) 64486.70 Da
IEP (calculated) 9.38
GRAVY (calculated) 0.12
Length 569 amino acids
Sequence (TAIR10)
(BLAST)
001: MATRCFWCWT TLLFCSQLLT GFARASSAGG AKEKGLSQTP TWAVALVCTF FILVSVLLEK ALHRVATWLW EKHKNSLLEA LEKIKAELMI LGFISLLLTF
101: GEQYILKICI PEKAAASMLP CPAPSTHDQD KTHRRRLAAA TTSSRCDEGH EPLIPATGLH QLHILLFFMA AFHILYSFIT MMLGRLKIRG WKKWEQETCS
201: HDYEFSIDPS RFRLTHETSF VRQHSSFWTK IPFFFYAGCF LQQFFRSVGR TDYLTLRHGF IAAHLAPGRK FDFQKYIKRS LEDDFKVVVG ISPLLWASFV
301: IFLLLNVNGW EALFWASILP VLIILAVSTK LQAILTRMAL GITERHAVVQ GIPLVHGSDK YFWFNRPQLL LHLLHFALFQ NAFQLTYFFW VWYSFGLKSC
401: FHTDFKLVIV KLSLGVGALI LCSYITLPLY ALVTQMGSNM KKAVFDEQMA KALKKWHMTV KKKKGKARKP PTETLGVSDT VSTSTSSFHA SGATLLRSKT
501: TGHSTASYMS NFEDQSMSDL EAEPLSPEPI EGHTLVRVGD QNTEIEYTGD ISPGNQFSFV KNVPANDID
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)