AT5G48100.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:extracellular 1.000 What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : Laccase/Diphenol oxidase family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes a protein that is similar to laccase-like polyphenol oxidases. Involved in lignin and flavonoids biosynthesis. It has four conserved copper binding domains. Expressed in developing testa, where it colocalizes with the flavonoid end products proanthocyanidins and flavonols. Mutant plants exhibited a delay in developmentally determined browning of the testa, characterized by the pale brown color of seed coat. The tt10 mutant seeds accumulate more epicatechin monomers and more soluble proanthocyanidins than wild-type seeds. Flavonol composition was also affected in tt10 seeds, which exhibited a higher ratio of quercetin rhamnoside monomers versus dimers than wild-type seeds. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
TRANSPARENT TESTA 10 (TT10); FUNCTIONS IN: copper ion binding, laccase activity; INVOLVED IN: lignin biosynthetic process, response to copper ion, flavonoid biosynthetic process; LOCATED IN: endomembrane system, apoplast; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, seedling growth, seed development stages; CONTAINS InterPro DOMAIN/s: Multicopper oxidase, type 3 (InterPro:IPR011707), Laccase (InterPro:IPR017761), Multicopper oxidase, type 2 (InterPro:IPR011706), Cupredoxin (InterPro:IPR008972), Multicopper oxidase, copper-binding site (InterPro:IPR002355), Multicopper oxidase, type 1 (InterPro:IPR001117); BEST Arabidopsis thaliana protein match is: laccase 14 (TAIR:AT5G09360.1); Has 10402 Blast hits to 8649 proteins in 1516 species: Archae - 36; Bacteria - 4416; Metazoa - 511; Fungi - 3532; Plants - 1551; Viruses - 0; Other Eukaryotes - 356 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr5:-:19489530..19492582 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 63997.50 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 7.51 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.16 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 565 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MSHSFFNLFL ISLFLYNNCI AHHYTFTVRE VPYTKLCSTK AILTVNSQFP GPIIKVHKGD TIYVNVQNRA SENITMHWHG VEQPRNPWSD GPEYITQCPI 101: RPGSDFLYKV IFSIEDTTVW WHAHSSWTRA TVHGLIFVYP RPPQILPFPK ADHEVPIILG EWWKRDVREV VEEFVRTGGA PNVSDALTIN GHPGFLYPCS 201: KSDTFHLTVE KGKTYRIRMV NAAMNLPLFF AIANHSLTVV SADGHYIKPI KATYITISPG ETLDMLLHAD QDPERTYYMA ARAYQSGNID FNNSTTIGIL 301: SYTSSCKAKT SSFSGYYPTL PFYNDTSAAF GFFTKIKCLF SGQVPVQISR RIITTVSINL RMCPQNSCEG PNGSRLAASM NNISFVTPSH VDILKAYYYH 401: IKGVYGTRFP EFPPLIFNFT AENQPLFLET PRLATEVKVI EFGQVVELVI QGTSLVGGGL DHPMHLHGFS FYVVGVGFGN YNISEEDPSS RYNLYDPPYK 501: NTMTVPRNGW IAIRFVADNP GVWFMHCHLD RHQTWGMNVV FIVKNGREPN QQILPPPDDL PPCYE |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)