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AT5G42270.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : FtsH extracellular protease family
Curator
Summary (TAIR10)
VAR1 contains a conserved motif for ATPase and a metalloprotease characteristic to FtsH proteins, and is targeted into chloroplasts. A VAR1-fusion protein synthesized in vitro exhibited ATPase activity and partial metalloprotease activity. This protein is located to the thylakoid membrane and forms a complex with VAR2. FtsH1 (VAR1) and FtsH5 are interchangeable in thylakoid membranes.
Computational
Description (TAIR10)
VARIEGATED 1 (VAR1); FUNCTIONS IN: metallopeptidase activity, ATP-dependent peptidase activity, ATPase activity; INVOLVED IN: photoinhibition, PSII associated light-harvesting complex II catabolic process, protein catabolic process; LOCATED IN: thylakoid, chloroplast thylakoid membrane, chloroplast, chloroplast envelope; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41 (InterPro:IPR000642); BEST Arabidopsis thaliana protein match is: FTSH protease 1 (TAIR:AT1G50250.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioGrid:19482BRENDA:3.4.24.B20EC:3.4.24.-eggNOG:COG0465
eggNOG:KOG0731EMBL:AB023032EMBL:AY126987EMBL:CP002688
EnsemblPlants:AT5G42270EnsemblPlants:AT5G42270.1entrez:834232Gene3D:3.40.50.300
GeneID:834232Genevisible:Q9FH02GO:GO:0004176GO:GO:0004222
GO:GO:0005524GO:GO:0006508GO:GO:0007275GO:GO:0008237
GO:GO:0009507GO:GO:0009534GO:GO:0009535GO:GO:0009579
GO:GO:0009735GO:GO:0009941GO:GO:0010205GO:GO:0010206
GO:GO:0010304GO:GO:0016021GO:GO:0016887GO:GO:0030163
GO:GO:0046872Gramene:AT5G42270.1HAMAP:MF_01458hmmpanther:PTHR23076
hmmpanther:PTHR23076:SF33HOGENOM:HOG000217276InParanoid:Q9FH02InterPro:IPR000642
InterPro:IPR003593InterPro:IPR003959InterPro:IPR003960InterPro:IPR005936
InterPro:IPR027417KEGG:ath:AT5G42270KO:K03798MEROPS:M41.024
OMA:FFWFFFMPaxDb:Q9FH02Pfam:PF00004Pfam:PF01434
Pfam:Q9FH02PhylomeDB:Q9FH02PRIDE:Q9FH02PRO:PR:Q9FH02
PROSITE:PS00674ProteinModelPortal:Q9FH02Proteomes:UP000006548RefSeq:NP_568604.1
scanprosite:PS00674SMART:SM00382SMR:Q9FH02STRING:3702.AT5G42270.1
SUPFAM:SSF140990SUPFAM:SSF52540TAIR:AT5G42270tair10-symbols:FTSH5
tair10-symbols:VAR1TIGRfam:TIGR01241TIGRFAMs:TIGR01241UniGene:At.21670
UniGene:At.66720UniProt:Q9FH02
Coordinates (TAIR10) chr5:+:16902659..16905102
Molecular Weight (calculated) 75236.00 Da
IEP (calculated) 5.13
GRAVY (calculated) -0.12
Length 704 amino acids
Sequence (TAIR10)
(BLAST)
001: MATTSSNPLL LSSNFLGSQI IISAPTPKTT TKSLPFSVIS RKRYQISQSE KLMKSLPSQA ALAALLFSSS SPQALAVNEP VQPPAPTITA EAQSPNLSTF
101: GQNVLMTAPN PQAQSSDLPD GTQWRYSEFL NAVKKGKVER VKFSKDGSVL QLTAVDNRRA TVIVPNDPDL IDILAMNGVD ISVSEGEGGN GLFDFIGNLL
201: FPLLAFGGLF YLFRGGQGGA GGPGGLGGPM DFGRSKSKFQ EVPETGVTFG DVAGADQAKL ELQEVVDFLK NPDKYTALGA KIPKGCLLVG PPGTGKTLLA
301: RAVAGEAGVP FFSCAASEFV ELFVGVGASR VRDLFEKAKS KAPCIVFIDE IDAVGRQRGA GMGGGNDERE QTINQLLTEM DGFSGNSGVI VLAATNRPDV
401: LDSALLRPGR FDRQVTVDRP DVAGRVQILK VHSRGKAIGK DVDYEKVARR TPGFTGADLQ NLMNEAAILA ARRELKEISK DEISDALERI IAGPEKKNAV
501: VSEEKKRLVA YHEAGHALVG ALMPEYDPVA KISIIPRGQA GGLTFFAPSE ERLESGLYSR SYLENQMAVA LGGRVAEEVI FGDENVTTGA SNDFMQVSRV
601: ARQMVERFGF SKKIGQVAVG GAGGNPFLGQ SMSSQKDYSM ATADVVDAEV RELVEKAYVR AKEIITTQID ILHKLAQLLI EKETVDGEEF MSLFIDGQAE
701: LYVS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)