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AT3G56240.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
peroxisome 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31871212 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:27137770 (2016): plastid plastid stroma
  • PMID:26781341 (2016): plasma membrane
  • PMID:24124904 (2013): plastid
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:19329564 (2009): peroxisome
  • PMID:18431481 (2008): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : copper chaperone
Curator
Summary (TAIR10)
CCH protein belongs to a family of eukaryotic proteins that participate in intracellular copper homeostasis by delivering this metal to the secretory pathway; mainly located along the vascular bundles of senescing leaves and petioles as well as in stem sieve elements; hypothesized to have a role in copper mobilization from decaying organs towards reproductive structures, as a result of metalloprotein breakdown. The plant-specific C-terminal domain of the CCH protein forms amyloid-like fibrils in vitro.
Computational
Description (TAIR10)
copper chaperone (CCH); FUNCTIONS IN: copper chaperone activity; INVOLVED IN: in 6 processes; LOCATED IN: chloroplast; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121); BEST Arabidopsis thaliana protein match is: homolog of anti-oxidant 1 (TAIR:AT1G66240.1); Has 2051 Blast hits to 1937 proteins in 366 species: Archae - 10; Bacteria - 382; Metazoa - 168; Fungi - 207; Plants - 1221; Viruses - 0; Other Eukaryotes - 63 (source: NCBI BLink).
Protein Annotations
BioGrid:10106eggNOG:COG2608eggNOG:KOG1603EMBL:AF361860
EMBL:AL163763EMBL:AY066056EMBL:AY085657EMBL:CP002686
EMBL:U88711EnsemblPlants:AT3G56240EnsemblPlants:AT3G56240.1entrez:824790
GeneID:824790Genevisible:O82089GO:GO:0006825GO:GO:0006878
GO:GO:0009507GO:GO:0009651GO:GO:0016531GO:GO:0046686
GO:GO:0046914GO:GO:0048046Gramene:AT3G56240.1hmmpanther:PTHR22814
hmmpanther:PTHR22814:SF73HOGENOM:HOG000038877InParanoid:O82089IntAct:O82089
InterPro:IPR006121KEGG:ath:AT3G56240KO:K07213OMA:IVFGLCC
PaxDb:O82089Pfam:O82089Pfam:PF00403Pfscan:PS50846
PhylomeDB:O82089PIR:T47741PRIDE:O82089PRO:PR:O82089
PROSITE:PS50846ProteinModelPortal:O82089Proteomes:UP000006548RefSeq:NP_191183.1
SMR:O82089STRING:3702.AT3G56240.1SUPFAM:SSF55008TAIR:AT3G56240
tair10-symbols:CCHUniGene:At.24871UniProt:O82089
Coordinates (TAIR10) chr3:-:20863460..20864402
Molecular Weight (calculated) 12971.30 Da
IEP (calculated) 4.60
GRAVY (calculated) -0.51
Length 121 amino acids
Sequence (TAIR10)
(BLAST)
001: MAQTVVLKVG MSCQGCVGAV NRVLGKMEGV ESFDIDIKEQ KVTVKGNVEP EAVFQTVSKT GKKTSYWPVE AEAEPKAEAD PKVETVTETK TEAETKTEAK
101: VDAKADVEPK AAEAETKPSQ V
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)