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AT3G03780.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31871212 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:31541795 (2020): plasma membrane
  • PMID:31520498 (2020): mitochondrion
  • PMID:31186290 (2019): cytosol None
  • PMID:31023727 (2019): mitochondrion
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:29104584 (2017): nucleus nuclear matrix nucleolus
  • PMID:27122571 (2016): mitochondrion
  • PMID:26781341 (2016): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24727099 (2014): mitochondrion
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:22550958 (2012): plastid
  • PMID:22318864 (2012): plasma membrane
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:21311031 (2011): mitochondrion
  • PMID:21166475 (2011): cytosol
  • PMID:19334764 (2009): plasma membrane
  • PMID:18998720 (2009): extracellular region
  • PMID:18431481 (2008): plastid
  • PMID:17644812 (2007): plasma membrane
  • PMID:15028209 (2004): plastid
  • PMID:12938931 (2003): plastid
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : methionine synthase 2
Curator
Summary (TAIR10)
Encodes a cytosolic methionine synthase, involved in methionine regeneration via the activated methyl cycle (or SAM cycle)
Computational
Description (TAIR10)
methionine synthase 2 (MS2); FUNCTIONS IN: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity, methionine synthase activity; INVOLVED IN: response to cadmium ion, response to salt stress, methionine biosynthetic process; LOCATED IN: cytosol, apoplast, plasma membrane, chloroplast, chloroplast envelope; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, seedling growth; CONTAINS InterPro DOMAIN/s: Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal (InterPro:IPR013215), Methionine synthase, vitamin-B12 independent (InterPro:IPR002629), 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (InterPro:IPR006276); BEST Arabidopsis thaliana protein match is: Cobalamin-independent synthase family protein (TAIR:AT5G17920.2); Has 4502 Blast hits to 4490 proteins in 1700 species: Archae - 186; Bacteria - 3282; Metazoa - 14; Fungi - 208; Plants - 251; Viruses - 2; Other Eukaryotes - 559 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G03780-MONOMERBioCyc:ARA:GQT-1023-MONOMERBioCyc:ARA:GQT-1024-MONOMERBioCyc:MetaCyc:AT3G03780-MONOMER
BioGrid:6480EC:2.1.1.14eggNOG:COG0620eggNOG:KOG2263
EMBL:AC009540EMBL:AJ608674EMBL:AY040010EMBL:AY084559
EMBL:AY150385EMBL:CP002686EnsemblPlants:AT3G03780EnsemblPlants:AT3G03780.1
EnsemblPlants:AT3G03780.2EnsemblPlants:AT3G03780.3entrez:821147GeneID:821147
Genevisible:Q9SRV5GO:GO:0003871GO:GO:0005829GO:GO:0005886
GO:GO:0008270GO:GO:0008705GO:GO:0009506GO:GO:0009507
GO:GO:0009651GO:GO:0009941GO:GO:0046686GO:GO:0048046
GO:GO:0050667Gramene:AT3G03780.1Gramene:AT3G03780.2Gramene:AT3G03780.3
gramene_pathway:2.1.1.14gramene_pathway:PWY-5041gramene_pathway:PWY-702gramene_plant_reactome:1119400
gramene_plant_reactome:6874919HAMAP:MF_00172hmmpanther:PTHR30519hmmpanther:PTHR30519:SF0
HOGENOM:HOG000246221InParanoid:Q9SRV5IntAct:Q9SRV5InterPro:IPR002629
InterPro:IPR006276InterPro:IPR013215KEGG:00270+2.1.1.14KEGG:00450+2.1.1.14
KEGG:ath:AT3G03780KO:K00549OMA:QAFSGAYPaxDb:Q9SRV5
Pfam:PF01717Pfam:PF08267Pfam:Q9SRV5PhylomeDB:Q9SRV5
PIRSF:PIRSF000382PRIDE:Q9SRV5PRO:PR:Q9SRV5ProteinModelPortal:Q9SRV5
Proteomes:UP000006548RefSeq:NP_001118564.1RefSeq:NP_187028.1RefSeq:NP_850507.1
SABIO-RK:Q9SRV5SMR:Q9SRV5STRING:3702.AT3G03780.1SUPFAM:SSF51726
TAIR:AT3G03780tair10-symbols:ATMS2tair10-symbols:MS2TIGRfam:TIGR01371
TIGRFAMs:TIGR01371UniGene:At.18359UniPathway:UPA00051UniProt:Q9SRV5
Coordinates (TAIR10) chr3:+:957602..960740
Molecular Weight (calculated) 84588.40 Da
IEP (calculated) 6.47
GRAVY (calculated) -0.15
Length 765 amino acids
Sequence (TAIR10)
(BLAST)
001: MASHIVGYPR MGPKRELKFA LESFWDGKSS ADDLQKVSAD LRSDIWKQMS AAGIKYIPSN TFSHYDQVLD TTAMLGAVPS RYGFTSGEIG LDVYFSMARG
101: NASVPAMEMT KWFDTNYHYI VPELGPEVKF SYASHKAVNE YKEAKALGVE TVPVLVGPVS YLLLSKLAKG VDKSFDLLSL LPKILPVYKE VIAELKAAGA
201: SWIQLDEPLF VMDLEGHKLQ AFSGAYAELE STLSGLNVLV ETYFADIPAE AYKTLTSLKG VTAFGFDLVR GTKTIDLIKS GFPQGKYLFA GVVDGRNIWA
301: NDLAASLITL QSLEGVVGKD KLVVSTSCSL LHTAVDLINE TKLDAEIKSW LAFAAQKVVE VDALAKALAG QTNESFFTAN ADALSSRRSS PRVTNESVQK
401: AAAALKGSDH RRTTEVSARL DAQQKKLNLP ILPTTTIGSF PQTVELRRVR REYKAKKISE EDYVKAIKEE IKKVVDIQED LDIDVLVHGE PERNDMVEYF
501: GEQLSGFAFT ANGWVQSYGS RCVKPPVIYG DVSRPKPMTV FWSSTAQSMT KRPMKGMLTG PVTILNWSFV RNDQPRHETC YQIALAIKDE VEDLEKGGIG
601: VIQIDEAALR EGLPLRKAEH SFYLDWAVHS FRITNCGVQD STQIHTHMCY SNFNDIIHSI IDMDADVITI ENSRSDEKLL SVFREGVKYG AGIGPGVYDI
701: HSPRIPSTDE IADRINKMLA VLEQNILWVN PDCGLKTRKY TEVKPALKAM VDAAKLIRSQ LGSAK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)