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AT3G01120.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Pyridoxal phosphate (PLP)-dependent transferases superfamily protein
Curator
Summary (TAIR10)
encodes a cystathionine gamma-synthase, which performs the first committed step in methionine biosynthesis. A conserved motif of 13 amino acids in the first exon is required for posttranscriptional autoregulation. This enzyme shares the same substrate as threonine synthase (TS) and its absence transcriptionally affects 8 genes in the genome.
Computational
Description (TAIR10)
METHIONINE OVERACCUMULATION 1 (MTO1); FUNCTIONS IN: cystathionine gamma-synthase activity; INVOLVED IN: methionine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT1G33320.1); Has 21364 Blast hits to 20702 proteins in 2452 species: Archae - 220; Bacteria - 11705; Metazoa - 241; Fungi - 842; Plants - 284; Viruses - 13; Other Eukaryotes - 8059 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G01120-MONOMERBioCyc:MetaCyc:AT3G01120-MONOMERBRENDA:2.5.1.48EC:2.5.1.48
eggNOG:COG0626eggNOG:KOG0053EMBL:AB010888EMBL:AC008261
EMBL:AF039206EMBL:AY091062EMBL:AY094438EMBL:BT002753
EMBL:CP002686EMBL:U43709EMBL:U83500EMBL:X79707
EMBL:X94756EnsemblPlants:AT3G01120EnsemblPlants:AT3G01120.1entrez:821292
Gene3D:3.40.640.10Gene3D:3.90.1150.10GeneID:821292Genevisible:P55217
GO:GO:0001887GO:GO:0003962GO:GO:0009086GO:GO:0009507
GO:GO:0009570GO:GO:0030170Gramene:AT3G01120.1gramene_pathway:2.5.1.-
gramene_pathway:PWY-702hmmpanther:PTHR11808hmmpanther:PTHR11808:SF14HOGENOM:HOG000246415
InParanoid:P55217InterPro:IPR000277InterPro:IPR015421InterPro:IPR015422
InterPro:IPR015424KEGG:ath:AT3G01120KO:K01739OMA:FLAIVNC
PANTHER:PTHR11808PaxDb:P55217Pfam:P55217Pfam:PF01053
PhylomeDB:P55217PIR:S51579PIR:S71228PRIDE:P55217
PRO:PR:P55217PROSITE:PS00868ProteinModelPortal:P55217Proteomes:UP000006548
RefSeq:NP_186761.1SABIO-RK:P55217scanprosite:PS00868SMR:P55217
STRING:3702.AT3G01120.1SUPFAM:SSF53383TAIR:AT3G01120tair10-symbols:ATCYS1
tair10-symbols:CGStair10-symbols:CGS1tair10-symbols:MTO1UniGene:At.20198
UniPathway:UPA00051UniProt:P55217
Coordinates (TAIR10) chr3:-:39234..41865
Molecular Weight (calculated) 59921.80 Da
IEP (calculated) 6.87
GRAVY (calculated) 0.13
Length 563 amino acids
Sequence (TAIR10)
(BLAST)
001: MAVSSFQCPT IFSSSSISGF QCRSDPDLVG SPVGGSSRRR VHASAGISSS FTGDAGLSSR ILRFPPNFVR QLSIKARRNC SNIGVAQIVA AKWSNNPSSA
101: LPSAAAAAAT SSASAVSSAA SAAAASSAAA APVAAAPPVV LKSVDEEVVV AEEGIREKIG SVQLTDSKHS FLSSDGSLTV HAGERLGRGI VTDAITTPVV
201: NTSAYFFKKT AELIDFKEKR SVSFEYGRYG NPTTVVLEDK ISALEGAEST LVMASGMCAS TVMLLALVPA GGHIVTTTDC YRKTRIFMEN FLPKLGITVT
301: VIDPADIAGL EAAVNEFKVS LFFTESPTNP FLRCVDIELV SKICHKRGTL VCIDGTFATP LNQKALALGA DLVVHSATKY IGGHNDVLAG CICGSLKLVS
401: EIRNLHHVLG GTLNPNAAYL IIRGMKTLHL RVQQQNSTAF RMAEILEAHP KVSHVYYPGL PSHPEHELAK RQMTGFGGVV SFEIDGDIET TIKFVDSLKI
501: PYIAPSFGGC ESIVDQPAIM SYWDLPQEER LKYGIKDNLV RFSFGVEDFE DVKADILQAL EAI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)