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AT2G30360.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data
Description (TAIR10) protein_coding : SOS3-interacting protein 4
Curator
Summary (TAIR10)
Encodes a SOS2-like protein kinase that is a member of the CBL-interacting protein kinase family.Loss of function mutants show a decrease in sensitivity to high pH.Phosphorylates AHA2, a plasma membrane H+ ATPase.This phosphorylation appears to regulate the activity of the proton transporter.
Computational
Description (TAIR10)
SOS3-interacting protein 4 (SIP4); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), NAF/FISL domain (InterPro:IPR018451), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), NAF domain (InterPro:IPR004041), CBL-interacting protein kinase (InterPro:IPR020660), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: serine/threonine protein kinase 1 (TAIR:AT5G01820.1); Has 132389 Blast hits to 130226 proteins in 4650 species: Archae - 184; Bacteria - 15582; Metazoa - 48520; Fungi - 13393; Plants - 32054; Viruses - 541; Other Eukaryotes - 22115 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G30360-MONOMERBioGrid:2935EC:2.7.11.1eggNOG:COG0515
eggNOG:KOG0583EMBL:AC002338EMBL:AF295666EMBL:AF339146
EMBL:AF370595EMBL:AF428398EMBL:BT002478EMBL:BT006582
EMBL:CP002685EnsemblPlants:AT2G30360EnsemblPlants:AT2G30360.1entrez:817586
GeneID:817586Genevisible:O22932GO:GO:0004672GO:GO:0004674
GO:GO:0005524GO:GO:0006468GO:GO:0007165GO:GO:0009268
Gramene:AT2G30360.1hmmpanther:PTHR24347hmmpanther:PTHR24347:SF220HOGENOM:HOG000233016
InParanoid:O22932IntAct:O22932InterPro:IPR000719InterPro:IPR004041
InterPro:IPR008271InterPro:IPR011009InterPro:IPR017441InterPro:IPR018451
InterPro:IPR020636iPTMnet:O22932KEGG:04150+2.7.11.1KEGG:04151+2.7.11.1
KEGG:ath:AT2G30360MINT:MINT-189416OMA:IGICISRPANTHER:PTHR24347
PaxDb:O22932Pfam:O22932Pfam:PF00069Pfam:PF03822
Pfscan:PS50011Pfscan:PS50816PhylomeDB:O22932PIR:E84707
PRIDE:O22932PRO:PR:O22932PROSITE:PS00107PROSITE:PS00108
PROSITE:PS50011PROSITE:PS50816ProteinModelPortal:O22932Proteomes:UP000006548
RefSeq:NP_180595.1scanprosite:PS00107scanprosite:PS00108SMART:SM00220
SMR:O22932STRING:3702.AT2G30360.1SUPFAM:SSF56112TAIR:AT2G30360
tair10-symbols:CIPK11tair10-symbols:PKS5tair10-symbols:SIP4tair10-symbols:SNRK3.22
UniGene:At.12244UniProt:O22932
Coordinates (TAIR10) chr2:-:12937265..12938572
Molecular Weight (calculated) 49020.10 Da
IEP (calculated) 8.36
GRAVY (calculated) -0.32
Length 435 amino acids
Sequence (TAIR10)
(BLAST)
001: MPEIEIAAGS GDNNDALFGK YELGKLLGCG AFAKVFHARD RRTGQSVAVK ILNKKKLLTN PALANNIKRE ISIMRRLSHP NIVKLHEVMA TKSKIFFAME
101: FVKGGELFNK ISKHGRLSED LSRRYFQQLI SAVGYCHARG VYHRDLKPEN LLIDENGNLK VSDFGLSALT DQIRPDGLLH TLCGTPAYVA PEILSKKGYE
201: GAKVDVWSCG IVLFVLVAGY LPFNDPNVMN MYKKIYKGEY RFPRWMSPDL KRFVSRLLDI NPETRITIDE ILKDPWFVRG GFKQIKFHDD EIEDQKVESS
301: LEAVKSLNAF DLISYSSGLD LSGLFAGCSN SSGESERFLS EKSPEMLAEE VEGFAREENL RMKKKKEEEY GFEMEGQNGK FGIGICISRL NDLLVVVEAR
401: RRGGDGDCYK EMWNGKLRVQ LIRVCDQTSS TNAAI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)