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AT2G21170.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
ASURE: plastid
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : triosephosphate isomerase
Curator
Summary (TAIR10)
Encodes a plastidic triose phosphate isomerase. Mutants with reduced pdTPI levels have difficulty transitioning from heterotrophic to autotrophic growth. The related phenotypes, such as chlorosis in light-grown seedlings may result from an accumulation of dihydroxyacetone phosphate (DHAP) and methylglyoxal (MG) in these mutants. Both splice variants appear to be expressed, but the At2g21170.2 variant appears to have a much narrower expression range limited to roots.
Computational
Description (TAIR10)
triosephosphate isomerase (TIM); FUNCTIONS IN: triose-phosphate isomerase activity; INVOLVED IN: in 7 processes; LOCATED IN: in 6 components; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Triosephosphate isomerase, active site (InterPro:IPR020861), Aldolase-type TIM barrel (InterPro:IPR013785), Triosephosphate isomerase (InterPro:IPR000652); BEST Arabidopsis thaliana protein match is: triosephosphate isomerase (TAIR:AT3G55440.1); Has 11587 Blast hits to 11585 proteins in 3635 species: Archae - 138; Bacteria - 6210; Metazoa - 1207; Fungi - 243; Plants - 472; Viruses - 0; Other Eukaryotes - 3317 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G21170-MONOMERBioCyc:ARA:GQT-2652-MONOMERBioGrid:2005EC:5.3.1.1
eggNOG:COG0149eggNOG:KOG1643EMBL:AC006264EMBL:AF247559
EMBL:AF378898EMBL:AY052748EMBL:AY087893EMBL:CP002685
EnsemblPlants:AT2G21170EnsemblPlants:AT2G21170.1entrez:816652ExpressionAtlas:Q9SKP6
Gene3D:3.20.20.70GeneID:816652Genevisible:Q9SKP6GO:GO:0004807
GO:GO:0005739GO:GO:0005829GO:GO:0006094GO:GO:0006096
GO:GO:0006642GO:GO:0009507GO:GO:0009570GO:GO:0009579
GO:GO:0009658GO:GO:0009941GO:GO:0019253GO:GO:0019563
GO:GO:0032504GO:GO:0046166GO:GO:0048046GO:GO:0080022
gramene_pathway:5.3.1.1gramene_pathway:CALVIN-PWYgramene_pathway:GLYCOLYSISgramene_pathway:PWY-1042
gramene_plant_reactome:1119424gramene_plant_reactome:1119519gramene_plant_reactome:6876923gramene_plant_reactome:6877176
HAMAP:MF_00147_Bhmmpanther:PTHR21139hmmpanther:PTHR21139:SF7HOGENOM:HOG000226413
InParanoid:Q9SKP6IntAct:Q9SKP6InterPro:IPR000652InterPro:IPR013785
InterPro:IPR020861InterPro:IPR022896iPTMnet:Q9SKP6KEGG:00010+5.3.1.1
KEGG:00051+5.3.1.1KEGG:00562+5.3.1.1KEGG:00710+5.3.1.1OMA:CEMIRIA
PANTHER:PTHR21139PaxDb:Q9SKP6PDB:4OHQPDBsum:4OHQ
Pfam:PF00121Pfam:Q9SKP6Pfscan:PS51440PhylomeDB:Q9SKP6
PIR:A84598PRIDE:Q9SKP6PRO:PR:Q9SKP6PROSITE:PS00171
PROSITE:PS51440ProteinModelPortal:Q9SKP6Proteomes:UP000006548Reactome:R-ATH-70171
Reactome:R-ATH-70263RefSeq:NP_179713.1scanprosite:PS00171SMR:Q9SKP6
STRING:3702.AT2G21170.1SUPFAM:SSF51351TAIR:AT2G21170tair10-symbols:PDTPI
tair10-symbols:TIMTIGRfam:TIGR00419TIGRFAMs:TIGR00419UniGene:At.24668
UniGene:At.31909unipathway:UPA00109UniPathway:UPA00116unipathway:UPA00138
UniProt:Q9SKP6World-2DPAGE:0003:Q9SKP6
Coordinates (TAIR10) chr2:-:9071047..9073106
Molecular Weight (calculated) 33347.50 Da
IEP (calculated) 7.98
GRAVY (calculated) -0.07
Length 315 amino acids
Sequence (TAIR10)
(BLAST)
001: MAATSLTAPP SFSGLRRISP KLDAAAVSSH QSFFHRVNSS TRLVSSSSSS HRSPRGVVAM AGSGKFFVGG NWKCNGTKDS IAKLISDLNS ATLEADVDVV
101: VSPPFVYIDQ VKSSLTDRID ISGQNSWVGK GGAFTGEISV EQLKDLGCKW VILGHSERRH VIGEKDEFIG KKAAYALSEG LGVIACIGEK LEEREAGKTF
201: DVCFAQLKAF ADAVPSWDNI VVAYEPVWAI GTGKVASPQQ AQEVHVAVRG WLKKNVSEEV ASKTRIIYGG SVNGGNSAEL AKEEDIDGFL VGGASLKGPE
301: FATIVNSVTS KKVAA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)