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AT2G20990.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
endoplasmic reticulum 0.500
plasma membrane 0.500
ASURE: endoplasmic reticulum,plasma membrane
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:32219438 (2020): cytosol
  • PMID:31818904 (2020): mitochondrion
  • PMID:31541795 (2020): plasma membrane
  • PMID:31520498 (2020): mitochondrion
  • PMID:31023727 (2019): mitochondrion
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:30447334 (2019): plasma membrane
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:26781341 (2016): plasma membrane
  • PMID:25900983 (2015): Golgi
  • PMID:25900983 (2015): Golgi Golgi apparatus Golgi membrane
  • PMID:25900983 (2015): Golgi trans-Golgi network
  • PMID:25900983 (2015): Golgi trans-Golgi network early endosome
  • PMID:25900983 (2015): Golgi trans-Golgi network multivesicular body
  • PMID:25900983 (2015): plant-type vacuole plant-type vacuole membrane
  • PMID:25641898 (2015): plasma membrane
  • PMID:23990937 (2013): plasma membrane
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:23396599 (2013): nucleus nuclear envelope nuclear inner membrane
  • PMID:22923678 (2012): endoplasmic reticulum
  • PMID:22318864 (2012): plasma membrane
  • PMID:22215637 (2012): plasma membrane
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21533090 (2011): extracellular region plant-type cell wall
  • PMID:21433285 (2011): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:17644812 (2007): plasma membrane
  • PMID:17317660 (2007): plasma membrane
  • PMID:15574830 (2004): plasma membrane
  • PMID:15539469 (2004): plant-type vacuole
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : synaptotagmin A
Curator
Summary (TAIR10)
Encodes a plasma membrane localized protein with similarity to synaptotagmins, a class of membrane trafficking proteins. SYT1 is expressed in all tissues. Loss of function mutations show hypersensitivity to NaCl and electrolyte leakage from the plasma membrane. SYT1 also affects calcium dependent freezing tolerance. SYT1 probably plays a role in membrane repair such as membrane resealing after freezing induced damage. Regulates endocytosis endosome recycling at the plasma membrane, but not membrane traffic along the secretory pathway.
Computational
Description (TAIR10)
synaptotagmin A (SYTA); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: in 7 processes; LOCATED IN: endosome, plasma membrane, vacuole, membrane; EXPRESSED IN: whole plant, guard cell, cultured cell, callus, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), C2 region (InterPro:IPR020477), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: Calcium-dependent lipid-binding (CaLB domain) family protein (TAIR:AT1G20080.1); Has 7068 Blast hits to 5182 proteins in 270 species: Archae - 0; Bacteria - 0; Metazoa - 4491; Fungi - 774; Plants - 1307; Viruses - 0; Other Eukaryotes - 496 (source: NCBI BLink).
Protein Annotations
BioGrid:1986EMBL:AB102951EMBL:AC006234EMBL:AC006264
EMBL:AJ617630EMBL:AY045836EMBL:AY087925EMBL:BT004371
EMBL:CP002685EnsemblPlants:AT2G20990EnsemblPlants:AT2G20990.1entrez:816633
ExpressionAtlas:Q9SKR2Gene3D:2.60.40.150GeneID:816633Genevisible:Q9SKR2
GO:GO:0005886GO:GO:0006897GO:GO:0008289GO:GO:0010008
GO:GO:0016021GO:GO:0016032GO:GO:0046872hmmpanther:PTHR10774
hmmpanther:PTHR10774:SF50HOGENOM:HOG000233385InParanoid:Q9SKR2InterPro:IPR000008
InterPro:IPR031468iPTMnet:Q9SKR2Pfam:PF00168Pfam:PF17047
Pfam:Q9SKR2Pfscan:PS50004PhylomeDB:Q9SKR2PIR:G84595
PRIDE:Q9SKR2PRINTS:PR00360PRO:PR:Q9SKR2PROSITE:PS50004
ProteinModelPortal:Q9SKR2Proteomes:UP000006548RefSeq:NP_565495.1SMART:SM00239
SMR:Q9SKR2SUPFAM:SSF49562SwissPalm:Q9SKR2TAIR:AT2G20990
tair10-symbols:ATSYTAtair10-symbols:NTMC2T1.1tair10-symbols:NTMC2TYPE1.1tair10-symbols:SYT1
tair10-symbols:SYTATMHMM:TMhelixUniGene:At.24916UniProt:Q9SKR2
Coordinates (TAIR10) chr2:+:9014827..9017829
Molecular Weight (calculated) 61747.50 Da
IEP (calculated) 7.67
GRAVY (calculated) -0.26
Length 541 amino acids
Sequence (TAIR10)
(BLAST)
001: MGFFSTILGF CGFGVGISLG LVIGYVLFVY LLPNDVKDPE IRSIADQDPK AMLRMLPEIP LWVKNPDFDR VDWINRFLEY MWPYLDKAIC KTAKNIAKPI
101: IEEQIPKYKI DSVEFETLTL GSLPPTFQGM KVYLTDEKEL IMEPCLKWAA NPNILVAIKA FGLKATVQVV DLQVFAQPRI TLKPLVPSFP CFANIYVSLM
201: EKPHVDFGLK LGGADLMSIP GLYRFVQEQI KDQVANMYLW PKTLVVPILD PAKAFRRPVG IVHVKVVRAV GLRKKDLMGG ADPFVKIKLS EDKIPSKKTT
301: VKHKNLNPEW NEEFKFSVRD PQTQVLEFSV YDWEQVGNPE KMGMNVLALK EMVPDEHKAF TLELRKTLDG GEDGQPPDKY RGKLEVELLY KPFTEEEMPK
401: GFEETQAVQK APEGTPAAGG MLVVIVHSAE DVEGKHHTNP YVRIYFKGEE RKTKHVKKNR DPRWNEEFTF MLEEPPVREK LHVEVLSTSS RIGLLHPKET
501: LGYVDIPVVD VVNNKRMNQK FHLIDSKNGK IQIELEWRTA S
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)