AT2G13560.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:mitochondrion 1.000 ASURE: mitochondrion What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : NAD-dependent malic enzyme 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes an NAD-dependent malic enzyme (NAD-ME) that does not act on oxaloacetate, indicating that it belongs to EC 1.1.1.39. It is a member of the alpha family of NAD-MEs in plants. It appears to function as a homodimer or as a heterodimer with the beta-type NAD-ME2 (At4g00570). NAD-ME1 transcript and protein levels are higher during the night than during the day. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
NAD-dependent malic enzyme 1 (NAD-ME1); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to salt stress, malate metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD-dependent malic enzyme 2 (TAIR:AT4G00570.1); Has 9465 Blast hits to 9448 proteins in 2440 species: Archae - 143; Bacteria - 6328; Metazoa - 607; Fungi - 221; Plants - 457; Viruses - 0; Other Eukaryotes - 1709 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr2:+:5650089..5655103 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 69659.80 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 5.10 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.23 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 623 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MGIANKLRLS SSSLSRILHR RILYSSAVRS FTTSEGHRPT IVHKQGLDIL HDPWFNKGTA FTMTERNRLD LRGLLPPNVM DSEQQIFRFM TDLKRLEEQA 101: RDGPSDPNAL AKWRILNRLH DRNETMYYKV LINNIEEYAP IVYTPTVGLV CQNYSGLFRR PRGMYFSAED RGEMMSMVYN WPAEQVDMIV VTDGSRILGL 201: GDLGVHGIGI AVGKLDLYVA AAGINPQRVL PVMIDVGTNN EKLRNDPMYL GLQQRRLEDD DYIDVIDEFM EAVYTRWPHV IVQFEDFQSK WAFKLLQRYR 301: CTYRMFNDDV QGTAGVAIAG LLGAVRAQGR PMIDFPKMKI VVAGAGSAGI GVLNAARKTM ARMLGNTETA FDSAQSQFWV VDAQGLITEG RENIDPEAQP 401: FARKTKEMER QGLKEGATLV EVVREVKPDV LLGLSAVGGL FSKEVLEAMK GSTSTRPAIF AMSNPTKNAE CTPQDAFSIL GENMIFASGS PFKNVEFGNG 501: HVGHCNQGNN MYLFPGIGLG TLLSGAPIVS DGMLQAASEC LAAYMSEEEV LEGIIYPPIS RIRDITKRIA AAVIKEAIEE DLVEGYREMD AREIQKLDEE 601: GLMEYVENNM WNPEYPTLVY KDD |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)