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AT1G18870.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plastid 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : isochorismate synthase 2
Curator
Summary (TAIR10)
Encodes a protein with isochorismate synthase activity involved in phylloquinone biosynthesis. Mutant studies of this gene's function suggest that its function is redundant with that of ICS1 (AT1G7410).
Computational
Description (TAIR10)
isochorismate synthase 2 (ICS2); CONTAINS InterPro DOMAIN/s: Chorismate binding, C-terminal (InterPro:IPR015890), ADC synthase (InterPro:IPR005801), Isochorismate synthase (InterPro:IPR004561); BEST Arabidopsis thaliana protein match is: ADC synthase superfamily protein (TAIR:AT1G74710.1); Has 14372 Blast hits to 14368 proteins in 2522 species: Archae - 246; Bacteria - 10572; Metazoa - 5; Fungi - 239; Plants - 212; Viruses - 0; Other Eukaryotes - 3098 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-1940-MONOMERBRENDA:5.4.4.2EC:5.4.4.2eggNOG:COG1169
eggNOG:ENOG410IMYREMBL:AC011809EMBL:CP002684EMBL:EU589462
EnsemblPlants:AT1G18870EnsemblPlants:AT1G18870.1entrez:838468ExpressionAtlas:Q9M9V6
Gene3D:3.60.120.10GeneID:838468Genevisible:Q9M9V6GO:GO:0006952
GO:GO:0008909GO:GO:0009507GO:GO:0009536GO:GO:0009697
GO:GO:0042372gramene_pathway:5.4.4.2gramene_pathway:PWY-5791gramene_pathway:PWY-6406
hmmpanther:PTHR11236hmmpanther:PTHR11236:SF3HOGENOM:HOG000006336InParanoid:Q9M9V6
InterPro:IPR004561InterPro:IPR005801InterPro:IPR015890KEGG:00130+5.4.4.2
KEGG:ath:AT1G18870KO:K02552ncoils:CoilOMA:SEWNELE
PaxDb:Q9M9V6Pfam:PF00425Pfam:Q9M9V6PhylomeDB:Q9M9V6
PIR:F86322PRIDE:Q9M9V6PRO:PR:Q9M9V6ProteinModelPortal:Q9M9V6
Proteomes:UP000006548RefSeq:NP_001154351.1RefSeq:NP_173321.4SMR:Q9M9V6
STRING:3702.AT1G18870.1SUPFAM:SSF56322TAIR:AT1G18870tair10-symbols:ATICS2
tair10-symbols:ICS2TIGRfam:TIGR00543TIGRFAMs:TIGR00543UniGene:At.43418
UniPathway:UPA00025UniProt:Q9M9V6
Coordinates (TAIR10) chr1:+:6515486..6519176
Molecular Weight (calculated) 62389.20 Da
IEP (calculated) 7.18
GRAVY (calculated) -0.26
Length 562 amino acids
Sequence (TAIR10)
(BLAST)
001: MASLQCSFHF LGTNPKKYNP SSIFQSYSRT SFTKLSSRVS RQRFLRCTLS MNGCEADHKA PLGTVETRTL STVPSPAAAT ERLITAVSDL KSQPPPFSSG
101: IVRLQVPIEQ KIGAIDWLHA QNEILPRSFF SRRSDSGRPD LLQDFSSDNG SSDHNPVSVA GIGSAVFFRD LDPFSHDDWR SIRRFLSSKS PLIRAYGGLR
201: FDPTGKIAVE WEHFGSFYFT VPQVEFDEFG GSSMLAATVA WDNELSWTLE NAIEALQETM LQVSSVIMRL RRESLGVIVV SKNHVPSEGA YYPAVNNALE
301: IIKDKHSPLS KVVLARSSRI ITDTDIDPIA WLARLQCEGQ DAYQFCLQPP GAPAFIGNTP ERLFHRKHLG VCSEALAATR PRGDSKVREM EIERDLLTSP
401: KDDLEFSIVR ENIREKLKTI CDRVVVKPHK SVRKLARVQH LYSQLAGQLK REDDEFNILT ALHPTPAVCG CPVEEARLLI KQIESFDRGM YAGPIGFFGG
501: GESEFSVGIR SALVEKGLGA LIYAGTGIVS GSNPSSEWNE LELKISQFTK SLEHESALQP IN
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)