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AT1G70730.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 0.661
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Phosphoglucomutase/phosphomannomutase family protein
Curator
Summary (TAIR10)
Encodes a cytosolic phosphoglucomutase (PGM). Two Arabidopsis PGM proteins (AT1G70730/PGM2 and AT1G23190/PGM3) have high sequence similarities and redundant functions. Mature plants possessing a single cPGM allele had a major reduction in cPGM activity. Whereas pgm2 and pgm3 single mutants are undistinguishable from the wild type, loss of both PGM2 and PGM3 severely impairs male and female gametophyte development.
Computational
Description (TAIR10)
Phosphoglucomutase/phosphomannomutase family protein; FUNCTIONS IN: intramolecular transferase activity, phosphotransferases, magnesium ion binding, phosphoglucomutase activity; INVOLVED IN: carbohydrate metabolic process; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Alpha-D-phosphohexomutase, conserved site (InterPro:IPR016066), Alpha-D-phosphohexomutase, C-terminal (InterPro:IPR005843), Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III (InterPro:IPR016055), Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (InterPro:IPR005846), Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (InterPro:IPR005845), Alpha-D-phosphohexomutase (InterPro:IPR005841), Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (InterPro:IPR005844); BEST Arabidopsis thaliana protein match is: Phosphoglucomutase/phosphomannomutase family protein (TAIR:AT1G23190.1); Has 6684 Blast hits to 6671 proteins in 2112 species: Archae - 92; Bacteria - 4940; Metazoa - 519; Fungi - 202; Plants - 162; Viruses - 0; Other Eukaryotes - 769 (source: NCBI BLink).
Protein Annotations
EMBL:CP002684EnsemblPlants:AT1G70730EnsemblPlants:AT1G70730.2entrez:843410
ExpressionAtlas:F4I6W3Gene3D:3.30.310.50Gene3D:3.40.120.10GeneID:843410
GO:GO:0000287GO:GO:0005975GO:GO:0016868Gramene:AT1G70730.2
gramene_pathway:5.4.2.2gramene_pathway:PWY-5661gramene_pathway:PWY-621gramene_pathway:PWY-622
gramene_pathway:PWY-842gramene_pathway:PWYQT-4437gramene_pathway:PWYQT-4466gramene_pathway:SUCSYN-PWY
hmmpanther:PTHR22573hmmpanther:PTHR22573:SF47InterPro:IPR005841InterPro:IPR005843
InterPro:IPR005844InterPro:IPR005845InterPro:IPR005846InterPro:IPR016055
InterPro:IPR016066KEGG:00520+5.4.2.10KEGG:ath:AT1G70730KO:K01835
Pfam:PF00408Pfam:PF02878Pfam:PF02879Pfam:PF02880
PRIDE:F4I6W3PRINTS:PR00509PROSITE:PS00710ProteinModelPortal:F4I6W3
Proteomes:UP000006548RefSeq:NP_001154464.1scanprosite:PS00710SMR:F4I6W3
SUPFAM:SSF53738SUPFAM:SSF55957TAIR:AT1G70730tair10-symbols:PGM2
UniGene:At.35274UniProt:F4I6W3
Coordinates (TAIR10) chr1:-:26669020..26673166
Molecular Weight (calculated) 65570.00 Da
IEP (calculated) 5.43
GRAVY (calculated) -0.13
Length 605 amino acids
Sequence (TAIR10)
(BLAST)
001: MFLLVTSCFL PDSGSSVKVS LFIFGVSLVS TSPIDGQKPG TSGLRKKVKV FKQPNYLENF VQATFNALTT EKVKGATLVV SGDGRYYSEQ AIQIIVKMAA
101: ANGVRRVWVG QNSLLSTPAV SAIIRERVGA DGSKATGAFI LTASHNPGGP TEDFGIKYNM ENGGPAPESI TDKIYENTKT IKEYPIAEDL PRVDISTIGI
201: TSFEGPEGKF DVEVFDSADD YVKLMKSIFD FESIKKLLSY PKFTFCYDAL HGVAGAYAHR IFVEELGAPE SSLLNCVPKE DFGGGHPDPN LTYAKELVAR
301: MGLSKTDDAG GEPPEFGAAA DGDADRNMIL GKRFFVTPSD SVAIIAANAV GAIPYFSSGL KGVARSMPTS AALDVVAKNL GLKFFEVPTG WKFFGNLMDA
401: GMCSVCGEES FGTGSDHIRE KDGIWAVLAW LSILAHKNKE TLDGNAKLVT VEDIVRQHWA TYGRHYYTRY DYENVDATAA KELMGLLVKL QSSLPEVNKI
501: IKGIHPEVAN VASADEFEYK DPVDGSVSKH QGIRYLFEDG SRLVFRLSGT GSEGATIRLY IEQYEKDASK IGRDSQDALG PLVDVALKLS KMQEFTGRSS
601: PTVIT
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)