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AT5G44610.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31541795 (2020): plasma membrane
  • PMID:26572690 (2016): extracellular region plant-type cell wall
  • PMID:24397334 (2014): plasma membrane
  • PMID:24030099 (2013): plasma membrane
  • PMID:19334764 (2009): plasma membrane
  • PMID:17317660 (2007): plasma membrane
  • PMID:16635983 (2006): plasma membrane
  • PMID:15060130 (2004): plasma membrane
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : microtubule-associated protein 18
Curator
Summary (TAIR10)
Encodes a protein with seven repeated VEEKK motifs. RNAi and overexpression experiments suggest that the gene is not involved in cell division but might be consequential for cell shape of epidermal and cortical cells. The protein encoded by this gene binds to cortical microtubules and inhibits tubulin polymerization. Associates to the plasma membrane and interacts with calmodulin and phosphatidylinositol phosphates, indicating an involvement in cellular signal transduction. Expression is enhanced by abiotic and hormonal factors. Induced during senescence.
Computational
Description (TAIR10)
microtubule-associated protein 18 (MAP18); FUNCTIONS IN: microtubule binding, calmodulin binding, phosphatidylinositol binding; INVOLVED IN: in 9 processes; LOCATED IN: cortical microtubule, plasma membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis; CONTAINS InterPro DOMAIN/s: DREPP plasma membrane polypeptide (InterPro:IPR008469); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
EMBL:AB024024EMBL:AK117253EMBL:AK318858EMBL:BT003705
EMBL:CP002688EMBL:JN624857EnsemblPlants:AT5G44610EnsemblPlants:AT5G44610.1
entrez:834489GeneID:834489Genevisible:Q9LU05GO:GO:0000902
GO:GO:0005516GO:GO:0005545GO:GO:0005737GO:GO:0005874
GO:GO:0005886GO:GO:0007165GO:GO:0008017GO:GO:0008360
GO:GO:0009409GO:GO:0009651GO:GO:0009737GO:GO:0009739
GO:GO:0010038GO:GO:0010150GO:GO:0031115GO:GO:0038023
GO:GO:0043622GO:GO:0046658GO:GO:0046685GO:GO:0048768
GO:GO:0090406GO:GO:1901981HOGENOM:HOG000153113InterPro:IPR008469
iPTMnet:Q9LU05KEGG:ath:AT5G44610OMA:FEKSPAKPaxDb:Q9LU05
Pfam:PF05558Pfam:Q9LU05PRIDE:Q9LU05PRO:PR:Q9LU05
ProteinModelPortal:Q9LU05Proteomes:UP000006548RefSeq:NP_568636.1STRING:3702.AT5G44610.1
TAIR:AT5G44610tair10-symbols:MAP18tair10-symbols:PCAP2UniGene:At.43801
UniProt:Q9LU05
Coordinates (TAIR10) chr5:-:17993718..17994224
Molecular Weight (calculated) 18550.10 Da
IEP (calculated) 4.57
GRAVY (calculated) -0.89
Length 168 amino acids
Sequence (TAIR10)
(BLAST)
001: MGYWKSKVVP RMKKLFEKSP AKKEVVEEEK PREVEVVEEV VVKTEEPAKE GETKPEEIIA TGEKEIEIVE EKKEEAKPVE VPVLAAAEEK KPAVEEEKKT
101: APVEEKKPAV EEEKKPAVEE KKPVEEEKKE VVAAVPVAET PSTKAPETPV VETPAKAPET PAAAPQKA
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)