AT3G60370.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:plastid 1.000 ASURE: plastid What is SUBAcon? |
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Experimental Localisations and PPI |
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FP Images |
Arabidopsis cell culture (plastidal marker)
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : FKBP-like peptidyl-prolyl cis-trans isomerase family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes an immunophilin, FKBP20-2, that belongs to the FK-506 binding protein (FKBP) subfamily functioning as peptidyl-prolyl isomerases (PPIases) in protein folding. FKBP20-2 has a unique pair of cysteines at the C terminus and was found to be reduced by thioredoxin (Trx) (itself reduced by NADPH by means of NADP-Trx reductase). The FKBP20-2 protein, which contains only two of the five amino acids required for catalysis, showed a low level of PPIase activity that was unaffected on reduction by Trx. Genetic disruption of the FKBP20-2 gene provide evidence that FKBP20-2 participates specifically in the accumulation of the PSII supercomplex in the chloroplast thylakoid lumen by means of a mechanism that has yet to be determined. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
FKBP-like peptidyl-prolyl cis-trans isomerase family protein; FUNCTIONS IN: FK506 binding, oxidoreductase activity, peptidyl-prolyl cis-trans isomerase activity; INVOLVED IN: photosystem II assembly; LOCATED IN: thylakoid, thylakoid lumen, chloroplast thylakoid lumen, chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidyl-prolyl cis-trans isomerase, FKBP-type (InterPro:IPR001179); BEST Arabidopsis thaliana protein match is: FKBP-like peptidyl-prolyl cis-trans isomerase family protein (TAIR:AT4G19830.1); Has 7131 Blast hits to 6812 proteins in 1455 species: Archae - 6; Bacteria - 3821; Metazoa - 1227; Fungi - 400; Plants - 644; Viruses - 0; Other Eukaryotes - 1033 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr3:-:22315000..22316533 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 27193.60 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 8.65 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.35 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 242 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MVTILSTPLS PRLTFLCETK LSLSRSNRSV CCSLSEEPKD QCLSRRSLVY VLVASPCLLL PALSSSAKTK SKSPYDERRL LEQNKRIQRE NNAPDEFPNF 101: VREGFEVKVL ASDNYIKADS GLIYRDFNVG QGDFPKDGQQ VTFHYIGYNE SGRRIDSTYI QGSPARIRMG TNALVPGFEM GIRDMKPGGR RRIIIPPELG 201: PPVGPSTFFS SKQFEVFDVE LLSIQNCERR TIIGFYSDVT CS |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)