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AT3G59420.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
plasma membrane 1.000
ASURE: plasma membrane
What is SUBAcon?
Predictors External Curations
AmiGO : plasma membrane 15772284
SwissProt : endoplasmic reticulum 16381842
SwissProt : plasma membrane 16381842
TAIR : plasma membrane 15772284
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:15255860 (2004): plasma membrane
  • PMID:11978870 (2002): extracellular region
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : crinkly4
Curator
Summary (TAIR10)
Encodes a membrane localized protein with similarity to receptor kinases which is involved in epidermal cell differentiation. Flowers of mutants have disorganized ovule integument growth and abnormal sepal margins. In the roots, mutants initiate more lateral roots but fewer laterals actually emerge due to defects in lateral root formation. Mutants also display disorganized columella. The root phenotypes can be traced to abnormalities in asymmetric divisions in the pericycle and root apex. Conflicting data regarding the role of the kinase domain- which may or may not be required for function. Complementation studies indicate that the C-terminal domain is also not required for signaling function. May be regulated by protein turnover which is mediated by endocytic processes.
Computational
Description (TAIR10)
crinkly4 (CR4); CONTAINS InterPro DOMAIN/s: TNFR/CD27/30/40/95 cysteine-rich region (InterPro:IPR001368), Protein kinase, ATP binding site (InterPro:IPR017441), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Regulator of chromosome condensation/beta-lactamase-inhibitor protein II (InterPro:IPR009091), Protein kinase, catalytic domain (InterPro:IPR000719); BEST Arabidopsis thaliana protein match is: CRINKLY4 related 2 (TAIR:AT2G39180.1); Has 114508 Blast hits to 112789 proteins in 4411 species: Archae - 95; Bacteria - 12671; Metazoa - 42599; Fungi - 9662; Plants - 32482; Viruses - 390; Other Eukaryotes - 16609 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G59420-MONOMERBioGrid:10426EC:2.7.11.1eggNOG:COG0515
eggNOG:ENOG410IF4AEMBL:AB074762EMBL:AL356014EMBL:CP002686
EnsemblPlants:AT3G59420EnsemblPlants:AT3G59420.1entrez:825111Gene3D:2.130.10.30
Gene3D:2.60.120.200GeneID:825111Genevisible:Q9LX29GO:GO:0004674
GO:GO:0005524GO:GO:0005886GO:GO:0007165GO:GO:0009786
GO:GO:0009793GO:GO:0009986GO:GO:0010311GO:GO:0016021
GO:GO:0019199GO:GO:0030139GO:GO:0032585GO:GO:0042803
GO:GO:0048364GO:GO:0048829Gramene:AT3G59420.1hmmpanther:PTHR27003
hmmpanther:PTHR27003:SF72HOGENOM:HOG000029541InParanoid:Q9LX29InterPro:IPR000719
InterPro:IPR001368InterPro:IPR008271InterPro:IPR009091InterPro:IPR011009
InterPro:IPR013320InterPro:IPR017441iPTMnet:Q9LX29KEGG:ath:AT3G59420
ncoils:CoilOMA:HLHGKNKPaxDb:Q9LX29Pfam:PF00069
Pfam:PF13540Pfam:Q9LX29Pfscan:PS50011Pfscan:PS50050
PhylomeDB:Q9LX29PIR:T49010PRIDE:Q9LX29PRO:PR:Q9LX29
PROSITE:PS00107PROSITE:PS00108PROSITE:PS50011PROSITE:PS50050
ProteinModelPortal:Q9LX29Proteomes:UP000006548RefSeq:NP_191501.1scanprosite:PS00107
scanprosite:PS00108SMART:SM00208SMART:SM00220SMR:Q9LX29
STRING:3702.AT3G59420.1SUPFAM:SSF50985SUPFAM:SSF56112TAIR:AT3G59420
tair10-symbols:ACR4tair10-symbols:CR4TMHMM:TMhelixUniGene:At.28062
UniProt:Q9LX29
Coordinates (TAIR10) chr3:-:21959871..21962558
Molecular Weight (calculated) 98186.40 Da
IEP (calculated) 7.33
GRAVY (calculated) -0.19
Length 895 amino acids
Sequence (TAIR10)
(BLAST)
001: MRMFETRARE WILLVKLVLF TSIWQLASAL GSMSSIAISY GEGGSVFCGL KSDGSHLVVC YGSNSAILYG TPGHLQFIGL TGGDGFMCGL LMLSHQPYCW
101: GNSAFIQMGV PQPMTKGAEY LEVSAGDYHL CGLRKPIVGR RKNSNIISSS LVDCWGYNMT RNFVFDKQLH SLSAGSEFNC ALSSKDKSVF CWGDENSSQV
201: ISLIPKEKKF QKIAAGGYHV CGILDGLESR VLCWGKSLEF EEEVTGTSTE EKILDLPPKE PLLAVVGGKF YACGIKRYDH SAVCWGFFVN RSTPAPTGIG
301: FYDLAAGNYF TCGVLTGTSM SPVCWGLGFP ASIPLAVSPG LCIDTPCPPG THELSNQENS PCKFTGSHIC LPCSTSCPPG MYQKSVCTER SDQVCVYNCS
401: SCSSHDCSSN CSSSATSGGK EKGKFWSLQL PIATAEIGFA LFLVAVVSIT AALYIRYRLR NCRCSENDTR SSKDSAFTKD NGKIRPDLDE LQKRRRARVF
501: TYEELEKAAD GFKEESIVGK GSFSCVYKGV LRDGTTVAVK RAIMSSDKQK NSNEFRTELD LLSRLNHAHL LSLLGYCEEC GERLLVYEFM AHGSLHNHLH
601: GKNKALKEQL DWVKRVTIAV QAARGIEYLH GYACPPVIHR DIKSSNILID EEHNARVADF GLSLLGPVDS GSPLAELPAG TLGYLDPEYY RLHYLTTKSD
701: VYSFGVLLLE ILSGRKAIDM HYEEGNIVEW AVPLIKAGDI NALLDPVLKH PSEIEALKRI VSVACKCVRM RGKDRPSMDK VTTALERALA QLMGNPSSEQ
801: PILPTEVVLG SSRMHKKSWR IGSKRSGSEN TEFRGGSWIT FPSVTSSQRR KSSASEGDVA EEEDEGRKQQ EALRSLEEEI GPASPGQSLF LHHNF
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)