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AT2G46370.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : Auxin-responsive GH3 family protein
Curator
Summary (TAIR10)
Encodes a jasmonate-amido synthetase that is a member of the GH3 family of proteins. JAR1 catalyzes the formation of a biologically active jasmonyl-isoleucine (JA-Ile) conjugate. JA-Ile promotes the interaction between JAZ1 and COI1 in the jasmonate signaling pathway. JAR1 localizes to the cytoplasm and is also a phytochrome A signaling component. JAR1 is an auxin-induced gene. Loss of function mutants are defective in a variety of responses to jasmonic acid. JAR1 has additional enzymatic activities in vitro, (e.g. the ability to synthesize adenosine 5'-tetraphosphate and other JA conjugates), but there are no data to show whether JAR1 catalyzes many of these reactions in vivo. JAR1 is involved in pathogen defense, sensitivity to ozone, and wound responses.
Computational
Description (TAIR10)
JASMONATE RESISTANT 1 (JAR1); FUNCTIONS IN: catalytic activity, adenylyltransferase activity, ATP binding, jasmonate-amino synthetase activity; INVOLVED IN: in 13 processes; LOCATED IN: vacuole, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GH3 auxin-responsive promoter (InterPro:IPR004993); BEST Arabidopsis thaliana protein match is: Auxin-responsive GH3 family protein (TAIR:AT4G03400.1); Has 1444 Blast hits to 1399 proteins in 231 species: Archae - 0; Bacteria - 474; Metazoa - 52; Fungi - 2; Plants - 663; Viruses - 0; Other Eukaryotes - 253 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT2G46370-MONOMERBioCyc:ARA:GQT-1919-MONOMERBioCyc:ARA:GQT-1920-MONOMERBioCyc:ARA:GQT-1921-MONOMER
BioGrid:4579EC:6.3.2.-eggNOG:ENOG410IE8CeggNOG:ENOG410XQH0
EMBL:AC006526EMBL:AF279129EMBL:AK221189EMBL:AK316746
EMBL:AK319095EMBL:AY050861EMBL:AY150437EMBL:CP002685
EMBL:Z26804EnsemblPlants:AT2G46370EnsemblPlants:AT2G46370.1EnsemblPlants:AT2G46370.2
entrez:819244ExpressionAtlas:Q9SKE2GeneID:819244Genevisible:Q9SKE2
GO:GO:0005737GO:GO:0009611GO:GO:0009694GO:GO:0009864
GO:GO:0010046GO:GO:0010224GO:GO:0019899GO:GO:0071365
GO:GO:0080123GO:GO:2000030gramene_pathway:6.3.-.-gramene_pathway:PWY-6220
gramene_plant_reactome:6787011gramene_plant_reactome:6877876hmmpanther:PTHR31901hmmpanther:PTHR31901:SF3
HOGENOM:HOG000238302InParanoid:Q9SKE2InterPro:IPR004993InterPro:IPR031110
iPTMnet:Q9SKE2KEGG:00220+6.3.2.-KEGG:00261+6.3.2.-KEGG:00380+6.3.2.-
KEGG:ath:AT2G46370KO:K14506ncoils:CoilPANTHER:PTHR31901
PANTHER:PTHR31901:SF3PaxDb:Q9SKE2PDB:4EPLPDBsum:4EPL
Pfam:PF03321Pfam:Q9SKE2PhylomeDB:Q9SKE2PIR:A84902
PRIDE:Q9SKE2PRO:PR:Q9SKE2ProteinModelPortal:Q9SKE2Proteomes:UP000006548
RefSeq:NP_001078069.1RefSeq:NP_566071.1RefSeq:NP_850453.1SMR:Q9SKE2
STRING:3702.AT2G46370.4TAIR:AT2G46370tair10-symbols:FIN219tair10-symbols:JAR1
UniGene:At.13902UniProt:Q9SKE2
Coordinates (TAIR10) chr2:+:19034342..19036369
Molecular Weight (calculated) 64354.00 Da
IEP (calculated) 5.40
GRAVY (calculated) -0.14
Length 575 amino acids
Sequence (TAIR10)
(BLAST)
001: MLEKVETFDM NRVIDEFDEM TRNAHQVQKQ TLKEILLKNQ SAIYLQNCGL NGNATDPEEA FKSMVPLVTD VELEPYIKRM VDGDTSPILT GHPVPAISLS
101: SGTSQGRPKF IPFTDELMEN TLQLFRTAFA FRNRDFPIDD NGKALQFIFS SKQYISTGGV PVGTATTNVY RNPNFKAGMK SITSPSCSPD EVIFSPDVHQ
201: ALYCHLLSGI LFRDQVQYVF AVFAHGLVHA FRTFEQVWEE IVTDIKDGVL SNRITVPSVR TAMSKLLTPN PELAETIRTK CMSLSNWYGL IPALFPNAKY
301: VYGIMTGSME PYVPKLRHYA GDLPLVSHDY GSSEGWIAAN VTPRLSPEEA TFAVIPNLGY FEFLPVSETG EGEEKPVGLT QVKIGEEYEV VITNYAGLYR
401: YRLGDVVKVI GFYNNTPQLK FICRRNLILS INIDKNTERD LQLSVESAAK RLSEEKIEVI DFSSYIDVST DPGHYAIFWE ISGETNEDVL QDCCNCLDRA
501: FIDAGYVSSR KCKTIGALEL RVVAKGTFRK IQEHFLGLGS SAGQFKMPRC VKPSNAKVLQ ILCENVVSSY FSTAF
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)