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AT1G64660.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : methionine gamma-lyase
Curator
Summary (TAIR10)
Encodes a functional methionine gamma-lyase, a cytosolic enzyme catalyzes the degradation of methionine into methanethiol, alpha-ketobutyrate and ammonia. The catabolism of excess methionine is important to methionine homeostasis.
Computational
Description (TAIR10)
methionine gamma-lyase (MGL); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT3G01120.1); Has 19547 Blast hits to 19544 proteins in 2474 species: Archae - 216; Bacteria - 11847; Metazoa - 211; Fungi - 771; Plants - 270; Viruses - 0; Other Eukaryotes - 6232 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G64660-MONOMERBioCyc:MetaCyc:AT1G64660-MONOMERBRENDA:4.4.1.11EC:4.4.1.11
eggNOG:COG0626eggNOG:KOG0053EMBL:AC009519EMBL:AF428413
EMBL:AK226375EMBL:AY054546EMBL:BT006588EMBL:CP002684
EnsemblPlants:AT1G64660EnsemblPlants:AT1G64660.1entrez:842774Gene3D:3.40.640.10
Gene3D:3.90.1150.10GeneID:842774Genevisible:Q9SGU9GO:GO:0005829
GO:GO:0009970GO:GO:0018826GO:GO:0019458GO:GO:0030170
GO:GO:0042631GO:GO:0051289Gramene:AT1G64660.1gramene_pathway:4.4.1.11
gramene_pathway:PWY-701hmmpanther:PTHR11808hmmpanther:PTHR11808:SF55HOGENOM:HOG000246415
InParanoid:Q9SGU9InterPro:IPR000277InterPro:IPR015421InterPro:IPR015422
InterPro:IPR015424KEGG:ath:AT1G64660KO:K01761OMA:SHYQYSR
PANTHER:PTHR11808PaxDb:Q9SGU9Pfam:PF01053Pfam:Q9SGU9
PhylomeDB:Q9SGU9PIR:G96669PIRSF:PIRSF001434PRIDE:Q9SGU9
PRO:PR:Q9SGU9ProteinModelPortal:Q9SGU9Proteomes:UP000006548RefSeq:NP_176647.1
SMR:Q9SGU9STRING:3702.AT1G64660.1SUPFAM:SSF53383TAIR:AT1G64660
tair10-symbols:ATMGLtair10-symbols:MGLUniGene:At.16566UniGene:At.35974
UniProt:Q9SGU9
Coordinates (TAIR10) chr1:+:24028977..24030537
Molecular Weight (calculated) 47823.40 Da
IEP (calculated) 5.99
GRAVY (calculated) -0.05
Length 441 amino acids
Sequence (TAIR10)
(BLAST)
001: MAHFLETQEP LVFSGKKRND RDDEDGDALV AKKSALAVCD ADPAAAIANI RHEFGEHGGV NMSIEASATF TVMEPDTMRR MFTGELGPDN DFYVYSRHFN
101: PTVLNLSRQM AALEGTQAAY CTSSGMSAIS SVMLQLCSSG GHVVAASTLY GGTHALLSHF LPRTCNITTS FVDITDHGAV ANAIVEGRTQ VLYFESVANP
201: TLTVADIPEL SRMAHEKGVT VVVDNTFAPM VLSPAKLGAD VVVHSISKFI SGGADIIAGA VCGSENLVKE MMDLRGGSLM LLGPTMNAKV AFELSERIPH
301: LGLRMREHSH RAQVYAERMR DLGMKVIYPG LETHPQHKLF KGMVNRDYGY GGLLSIDMET EEKANKLMAY LQNATQFGFM AVSLGYYETL MSCSGSSTSS
401: ELDPSQKEAA GISPGLVRMS VGYVGTLEQK WTQFEKAFLR M
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)