AT1G29690.1
|
Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:plasma membrane 1.000 What is SUBAcon? |
|
||||||||||||||||||||||||||||||||||||||||||||||||
| Experimental Localisations and PPI |
|
||||||||||||||||||||||||||||||||||||||||||||||||
|
SUBAcon links
AGI-AGI relationships |
|
||||||||||||||||||||||||||||||||||||||||||||||||
| Description (TAIR10) | protein_coding : MAC/Perforin domain-containing protein | ||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein containing a domain with significant homology to the MACPF (membrane attack complex and perforin) domain of complements and perforin proteins that are involved in innate immunity in animals. Transgenic <i>cad1-1</i> mutant plants show lesions seen in the hypersensitive response, as well as a spontaneous activation of expression of pathogenesis-related genes and leading to a 32-fold increase in salicylic acid (SA). CAD1 is postulated to act as a negative regulator controlling SA-mediated pathway of programmed cell death in plant immunity. | ||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
constitutively activated cell death 1 (CAD1); CONTAINS InterPro DOMAIN/s: Membrane attack complex component/perforin (MACPF) domain (InterPro:IPR020864); BEST Arabidopsis thaliana protein match is: MAC/Perforin domain-containing protein (TAIR:AT4G24290.2); Has 226 Blast hits to 225 proteins in 30 species: Archae - 0; Bacteria - 6; Metazoa - 14; Fungi - 0; Plants - 200; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
|
||||||||||||||||||||||||||||||||||||||||||||||||
| Coordinates (TAIR10) | chr1:-:10379310..10381861 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 62226.40 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 8.17 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.27 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 561 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MENRKGGNFS VPSSEALTTT LRNAIQALGR GFDVTSDVRL LYCKGAPGSR LVRIEEGQNR DLELSHGFLL PNVPADIDCS RGNSGTQRIS VCSFHEMAEE 101: FNVRSGVKGN IPLGCFNAMF NYTGSWQVDA ASTKSLALVG YFIPLYDVKL AKLTLVLHNE IRRAVPSSWD PASLASFIEN YGTHIVTSVT IGGRDVVYIR 201: QHQSSPLPVS EIENYVNDMI KHRFHEAESQ SITGPLKYKD KDITVIFRRR GGDDLEQSHA RWAETVPAAP DIINMTFTPI VSLLEGVPGL RHLTRAIELY 301: LEYKPPIEDL QYFLDYQIAR AWAPEQSNLQ RKEPVCSSLQ FSLMGPKLFI SADQVTVGRK PVTGLRLSLE GSKQNRLSIH LQHLVSLPKI LQPHWDSHVP 401: IGAPKWQGPE EQDSRWFEPI KWKNFSHVST SPIEHTETHI GDLSGVHIVT GAQLGVWDFG SKNVLHLKLL FSKVPGCTIR RSVWDHTPVA SSGRLEPGGP 501: STSSSTEEVS GQSGKLAKIV DSSEMLKGPQ DLPGHWLVTG AKLGVEKGKI VLRVKYSLLN Y |
||||||||||||||||||||||||||||||||||||||||||||||||
| See Also |
|
||||||||||||||||||||||||||||||||||||||||||||||||
Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)