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AT1G04510.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:30961429 (2019): nucleus
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:19334764 (2009): plasma membrane
  • PMID:15496452 (2005): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : MOS4-associated complex 3A
Curator
Summary (TAIR10)
Encodes MAC3A, a U-box proteins with homology to the yeast and human E3 ubiquitin ligase Prp19. Associated with the MOS4-Associated Complex (MAC). Involved in plant innate immunity.
Computational
Description (TAIR10)
MOS4-associated complex 3A (MAC3A); FUNCTIONS IN: ubiquitin-protein ligase activity, nucleotide binding; INVOLVED IN: response to cadmium ion, defense response to bacterium; LOCATED IN: nucleolus, nucleus, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), U box domain (InterPro:IPR003613), WD40 repeat (InterPro:IPR001680), Pre-mRNA-splicing factor 19 (InterPro:IPR013915), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: MOS4-associated complex 3B (TAIR:AT2G33340.2); Has 53700 Blast hits to 26315 proteins in 787 species: Archae - 70; Bacteria - 7824; Metazoa - 20612; Fungi - 11571; Plants - 6404; Viruses - 0; Other Eukaryotes - 7219 (source: NCBI BLink).
Protein Annotations
BioGrid:24738DNASU:839503EC:6.3.2.-eggNOG:ENOG410XPQV
eggNOG:KOG0289EMBL:AC000104EMBL:AK221436EMBL:AY039940
EMBL:AY142564EMBL:CP002684EnsemblPlants:AT1G04510EnsemblPlants:AT1G04510.1
entrez:839503ExpressionAtlas:Q94BR4Gene3D:2.130.10.10Gene3D:3.30.40.10
GeneID:839503Genevisible:Q94BR4GO:GO:0005634GO:GO:0005681
GO:GO:0005730GO:GO:0006281GO:GO:0006397GO:GO:0008380
GO:GO:0016874GO:GO:0042742GO:GO:0045087GO:GO:0046686
GO:GO:0061630GO:GO:0070534hmmpanther:PTHR22840HOGENOM:HOG000177308
InParanoid:Q94BR4IntAct:Q94BR4InterPro:IPR001680InterPro:IPR003613
InterPro:IPR013083InterPro:IPR013915InterPro:IPR015943InterPro:IPR017986
ncoils:CoilOMA:WAFSDIHPaxDb:Q94BR4Pfam:PF00400
Pfam:PF08606Pfam:Q94BR4Pfscan:PS50082Pfscan:PS50294
Pfscan:PS51698PhylomeDB:Q94BR4PIR:E86177PRIDE:Q94BR4
PRO:PR:Q94BR4PROSITE:PS50082PROSITE:PS50294PROSITE:PS51698
ProteinModelPortal:Q94BR4Proteomes:UP000006548Reactome:R-ATH-6781823Reactome:R-ATH-6782135
Reactome:R-ATH-6782210Reactome:R-ATH-72163RefSeq:NP_563708.1SMART:SM00320
SMART:SM00504SMR:Q94BR4STRING:3702.AT1G04510.1SUPFAM:SSF50978
SUPFAM:SSF57850TAIR:AT1G04510tair10-symbols:MAC3AUniGene:At.21449
UniPathway:UPA00143UniProt:Q94BR4
Coordinates (TAIR10) chr1:+:1226749..1230592
Molecular Weight (calculated) 56869.10 Da
IEP (calculated) 6.61
GRAVY (calculated) -0.31
Length 523 amino acids
Sequence (TAIR10)
(BLAST)
001: MNCAISGEVP EEPVVSKKSG LLYEKRLIQT HISDYGKCPV TGEPHTLDDI VPIKTGKIVK PKPLHTASIP GLLGTFQTEW DSLMLSNFAL EQQLHTARQE
101: LSHALYQHDA ACRVIARLKK ERDESRQLLA EAERQLPAAP EVATSNAALS NGKRGIDDGE QGPNAKKMRL GISAEVITEL TDCNAALSQQ RKKRQIPKTL
201: ASVDALEKFT QLSSHPLHKT NKPGIFSMDI LHSKDVIATG GIDTTAVLFD RPSGQILSTL TGHSKKVTSI KFVGDTDLVL TASSDKTVRI WGCSEDGNYT
301: SRHTLKDHSA EVRAVTVHAT NKYFVSASLD STWCFYDLSS GLCLAQVTDA SENDVNYTAA AFHPDGLILG TGTAQSIVKI WDVKSQANVA KFGGHNGEIT
401: SISFSENGYF LATAALDGVR LWDLRKLKNF RTFDFPDANS VEFDHSGSYL GIAASDIRVF QAASVKAEWN PIKTLPDLSG TGKATSVKFG LDSKYIAVGS
501: MDRNLRIFGL PDDDNTEDSA QDS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)