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AT5G04620.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : biotin F
Curator
Summary (TAIR10)
The cDNA encoding 7-keto-8-aminopelargonic acid (KAPA) synthase, the first committed enzyme of the biotin synthesis pathway has been cloned and its molecular function confirmed (functional complementation of an E. coli mutant). The subcellular localization of the enzyme (cytosol) proves that the biotin biosynthesis in plants takes place in different compartments which differs from the biosynthetic route found in microorganisms.
Computational
Description (TAIR10)
biotin F (BIOF); CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: long chain base2 (TAIR:AT5G23670.2); Has 10202 Blast hits to 10184 proteins in 2138 species: Archae - 77; Bacteria - 6906; Metazoa - 648; Fungi - 572; Plants - 222; Viruses - 9; Other Eukaryotes - 1768 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-825-MONOMERBRENDA:2.3.1.47EC:2.3.1.47eggNOG:COG0156
eggNOG:KOG1359EMBL:AK119095EMBL:AL162875EMBL:BT026507
EMBL:CP002688EMBL:DQ017966EnsemblPlants:AT5G04620EnsemblPlants:AT5G04620.1
EnsemblPlants:AT5G04620.2entrez:830339ExpressionAtlas:Q8GW43Gene3D:3.40.640.10
Gene3D:3.90.1150.10GeneID:830339Genevisible:Q8GW43GO:GO:0005777
GO:GO:0005829GO:GO:0008710GO:GO:0009102GO:GO:0030170
gramene_pathway:2.3.1.47gramene_pathway:PWY-3701hmmpanther:PTHR13693hmmpanther:PTHR13693:SF53
HOGENOM:HOG000221021InterPro:IPR004839InterPro:IPR015421InterPro:IPR015422
InterPro:IPR015424KEGG:ath:AT5G04620KO:K00652OMA:NAHRFLK
PaxDb:Q8GW43Pfam:PF00155PhylomeDB:Q8GW43PIR:T48458
ProteinModelPortal:Q8GW43Proteomes:UP000006548Reactome:R-ATH-189451RefSeq:NP_196082.2
RefSeq:NP_974731.1SMR:Q8GW43STRING:3702.AT5G04620.2SUPFAM:SSF53383
TAIR:AT5G04620tair10-symbols:ATBIOFtair10-symbols:BIOFTMHMM:TMhelix
UniGene:At.46019UniPathway:UPA00078UniProt:Q8GW43
Coordinates (TAIR10) chr5:+:1328004..1329934
Molecular Weight (calculated) 37310.50 Da
IEP (calculated) 8.91
GRAVY (calculated) 0.11
Length 343 amino acids
Sequence (TAIR10)
(BLAST)
001: MGPKGSALIC GYTTYHRLLE SSLAQLKKKE DCLVCPTGFA ANMAAMVAIG SVASLLAASG KPLKNEKVAI FSDALNHASI IDGVRLAERQ GNVEVFVYRH
101: CDMYHLNSLL SNCKMKRKVV VTDSLFSMDG DFAPMEELSQ LRKKYGFLLV IDDAHGTFVC GENGGGVAEE FNCEADVDLC VGTLSKAAGC HGGFIACSKK
201: WKQLIQSRGR SFIFSTAIPV PMAAAAYAAV VVARKEIWRR KAIWERVKEF KELSGVDISS PIISLVVGNQ EKALKASRYL LKSGFHVMAI RPPTVPPNSC
301: RLRVTLSAAH TTEDVKKLIT ALSSCLDFDN TATHIPSFLF PKL
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)