AT2G26260.1
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:golgi 0.582 What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes an enzyme with 3β-hydroxysteroid dehydrogenase/C4-decarboxylase activity <i>in vitro</i>. The activity of the enzyme was determined using microsomal extracts of yeast overexpressing the <i>Arabidopsis</i> gene. Cytosolic fractions failed to be associated to the activity, leading to the speculation that the enzyme is membrane-bound. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 (3BETAHSD/D2); FUNCTIONS IN: 3-beta-hydroxy-delta5-steroid dehydrogenase activity, sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; INVOLVED IN: steroid biosynthetic process, metabolic process; LOCATED IN: membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Reticulon (InterPro:IPR003388), NAD(P)-binding domain (InterPro:IPR016040), 3-beta hydroxysteroid dehydrogenase/isomerase (InterPro:IPR002225); BEST Arabidopsis thaliana protein match is: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1 (TAIR:AT1G47290.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr2:+:11178237..11182872 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 61707.80 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 8.58 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | 0.15 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Length | 564 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MSPAATETER WCVVTGGRGF AARHLVEMLV RYEMFCVRIA DLAPAIMLDP QEGNGVLDEG LRSGRVQYIS ADLRDKSQVV KAFQGAEVVF HMAAPDSSIN 101: NHQLQYSVNV QGTQNVIDAC VDVGVKRLIY TSSPSVVFDG VHGILNGTES MAYPIKHNDS YSATKAEGEE LIMKANGRNG LLTCCIRPSS IFGPGDRLLV 201: PSLVAAARAG KSKFIIGDGN NLYDFTYVEN VAHAHVCAER ALASGGDVST KAAGQAYFIT NMEPIKFWEF MSQLLDGLGY ERPSIKIPAF IMMPIAHLVE 301: LTYKVLGPYG MTVPQLTPSR VRLLSCSRTF DSTKAKDRLG YAPVVPLQEG IRRTIDSFSH LTAGSQSKRE GPSKASRILG GGKVADTLLW KDLKQTLIAI 401: FILISIYYNF VATGSTVVTA LSKALLVASV FLFLHGILPE KIFGYTVEKI PASQFHLSKD SSHDLSLSVI SSWNTTVKAL RSLCQGNDWS FFFKVVFVLL 501: ALSLAGAISL HSIFVIGLPI AFLAFLVYEK KEQEIDSIVV SFKSFACKHK SDVYEKLFGS KKHD |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)