AT1G18450.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : actin-related protein 4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a gene similar to actin-related proteins in other organisms. Member of nuclear ARP family of genes. Component of chromatin remodeling complexes, involved in chromatin-mediated gene regulation. Phenotype of the arp4-1 mutant allele revealed partial sterility due to defects in anther development. Targeting the distinct, 3' UTR of AtARP4 transcripts with RNA interference caused a drastic reduction in the level of AtARP4 protein expression, and resulted in strong pleiotropic phenotypes such as altered organization of plant organs, early flowering, delayed flower senescence and high levels of sterility. Western blot analysis and immunolabelling demonstrated a clear correlation between reductions in the level of AtARP4 expression and severity of the phenotypes. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
actin-related protein 4 (ARP4); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: long-day photoperiodism, flowering, chromatin organization, pollen sperm cell differentiation; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Actin/actin-like (InterPro:IPR004000); BEST Arabidopsis thaliana protein match is: actin-11 (TAIR:AT3G12110.1); Has 13669 Blast hits to 13362 proteins in 2792 species: Archae - 2; Bacteria - 480; Metazoa - 5593; Fungi - 3430; Plants - 1457; Viruses - 2; Other Eukaryotes - 2705 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr1:+:6348199..6351766 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 48939.30 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 4.99 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.36 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 441 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MYGGDEVSAI VVDLGSHTCK AGYAGEDAPK AVFPSVIGAV DGVEAMDVDV DSTKTNSNSE DSKTESEKEK SKRKLYVGSQ AMSYRRDHME VLSPIKDGIV 101: SDWDLVDNIW EHAFKSCLMI DPTEHPMLLA EPPLNTQQQR EKAAELMFEK YKVPALFMAK NPVLTSFATG RATSLVVDCG GGSTTISPVH DGYVLQKAVV 201: SSPLGGEFLT DCLLKSLESK GIKIRPRYSF KRKEVRAGEF QVEDVDIPDT TESYKLFCQR MIVGDIKDSI CRVPDTPYDD KSYSNIPTTS YELPDGQTLE 301: IGADRFKVPD VMFNPSIVQT IPGMEKYAEM IPSVRGLPHM VMESINKCDV DIRRELYSSI LLAGGTSSMQ QLKERLEKDL IEESPHSARV KVLASGNTTE 401: RRFSVWIGGS ILASLGSFQQ MWFSKSEYEE HGASYIQRKC P |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)