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AT4G18120.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no coexpression data no PPI data
Description (TAIR10) protein_coding : MEI2-like 3
Curator
Summary (TAIR10)
A member of mei2-like gene family, predominantly plant-based family of genes encoding RNA binding proteins with characteristic presence of a highly conserved RNA binding motif first described in the mei2 gene of the fission yeast S. pombe. In silico analyses reveal nine mei2 -like genes in A. thaliana. They were grouped into four distinct clades, based on overall sequence similarity and subfamily-specific sequence elements. AML3 is a member of two sister clades of mei2-like gene family, AML1 through AML5, and belongs to the clade named ALM235. Among mei2-like genes, AML3 is the transcript with highest frequency of alternative splicing. Expression was detected during early embryo development (heart and torpedo stage); no accumulation was detected in vegetative and floral apices, as revealed by in situ hybridization.
Computational
Description (TAIR10)
MEI2-like 3 (ML3); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), RNA recognition motif 2 (InterPro:IPR007201), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: MEI2-like protein 5 (TAIR:AT1G29400.2); Has 2869 Blast hits to 2722 proteins in 297 species: Archae - 8; Bacteria - 173; Metazoa - 1272; Fungi - 326; Plants - 696; Viruses - 0; Other Eukaryotes - 394 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT4G18120EnsemblPlants:AT4G18120.1entrez:827537hmmpanther:PTHR24012
hmmpanther:PTHR24012:SF390Pfam:PF00076Pfam:PF04059Pfscan:PS50102
tair10-symbols:AML3tair10-symbols:ML3
Coordinates (TAIR10) chr4:+:10038878..10041950
Molecular Weight (calculated) 81332.50 Da
IEP (calculated) 6.17
GRAVY (calculated) -0.61
Length 730 amino acids
Sequence (TAIR10)
(BLAST)
001: MNIPSGTFSR SDHFHASSDA SLFSSSLPLI QHQNINPRDS YHQSVDEMAS GLDHFSGGIG NMLDDGDSHP IGNMLPDDEE ELFSGLMDDL NLSSLPATLD
101: DLEDYDLFGS GGGLELETDP YDSLNKGFSR MGFADSNVDN VMPQNIFQNG VGSIAGEHPY GEHPSRTLFV RNINSNVEDS ELQALFEQLC EHYKAKLLKK
201: RKLDIHFSIP KDNPSEKDVN QGTLVVFNLA PSVSNRDLEN IFGVYGEIKE IRETPNKRHH KFVEFFDVRS ADAALKALNR TEIAGKRIKL EHSRPGGARR
301: NMMLQMNPEL EQDDSYSYLN HVESPLASSP IGNWRNSPID HPLQSFSKSP IFGNLSPTKN IRYPEFSMKT ASVNNDQEGR RFSHLDHLFS SSSYNNASHK
401: ASTFQQPQSF GSVSSFGSLN SHPSHVETLS GSEFLWGSPS SSAWPVNPFS SNRENHRFPY SAQNGSLHQL HHIGSAPSGF FPRSPETSSM GSVAFRGASG
501: NMNAQRNLRE TSSPNFKMLS APRRSQLFTG NGSYLWPAAT MVSIDDPLED GSNQQFDSNG NQADIKIQFQ LDLSKIMRGE DPRTTLMIKN IPNKYTRNML
601: LAAIDEKNSG TYDFLYLPID FKNKCNVGYA FINMVSPKFT IALYEAFNGK KWDKFNSEKV ASLAYARIQG KAALIAHFQN SSLMNEDRRC QPIVFDGSES
701: KYPIIRENSQ LEASNSTVSH PLVGENTHQS
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)