AT5G50950.3
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 0.500 mitochondrion 0.500 ASURE: cytosol,mitochondrion What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : FUMARASE 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a fumarase enzyme initially shown to be in the mitochondria through proteomic studies but later shown to be present in the cytosol using an RFP fluorescent protein tag. It appears to be important for the accumulation of fumarate from malate in leaves in the light, and helps to promote nitrogen assimilation under high nitrogen conditions. It does not appear to be necessary for lipid metabolism and seedling growth. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
FUMARASE 2 (FUM2); FUNCTIONS IN: fumarate hydratase activity, protein binding; INVOLVED IN: nitrate assimilation, response to salt stress, fumarate metabolic process; LOCATED IN: cytosol, mitochondrion; EXPRESSED IN: male gametophyte, guard cell, root, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Fumarate hydratase, class II (InterPro:IPR005677), L-Aspartase-like (InterPro:IPR008948), Fumarate lyase, conserved site (InterPro:IPR020557), Lyase 1, N-terminal (InterPro:IPR022761), Fumarase C, C-terminal (InterPro:IPR018951), Fumarate lyase (InterPro:IPR000362); BEST Arabidopsis thaliana protein match is: fumarase 1 (TAIR:AT2G47510.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:+:20729999..20733636 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 45282.50 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.75 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.09 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 423 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MPEPIVRAFG VLKKCAAKVN MEYGLDPMIG EAIMEAAQEV AEGKLNDHFP LVVWQTGSGT QSNMNANEVI ANRAAEILGH KRGEKIVHPN DHVNRSQSSN 101: DTFPTVMHIA AATEITSRLI PSLKNLHSSL ESKSFEFKDI VKIGRTHTQD ATPLTLGQEF GGYATQVEYG LNRVACTLPR IYQLAQGGTA VGTGLNTKKG 201: FDVKIAAAVA EETNLPFVTA ENKFEALAAH DACVETSGSL NTIATSLMKI ANDIRFLGSG PRCGLGELSL PENEPGSSIM PGKVNPTQCE ALTMVCAQVM 301: GNHVAVTIGG SNGHFELNVF KPVIASALLH SIRLIADASA SFEKNCVRGI EANRERISKL LHESLMLVTS LNPKIGYDNA AAVAKRAHKE GCTLKHAAMK 401: LGVLTSEEFD TLVVPEKMIG PSD |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)