AT5G40820.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : Ataxia telangiectasia-mutated and RAD3-related | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a Arabidopsis ortholog of the ATR protein kinase that is involved in a wide range of responses to DNA damage and plays a central role in cell-cycle regulation. Dominant loss of function alleles identified as suppressors of ALS also exhibit increased tolerance to aluminum. This may be due to the inhibition of terminal differentiation of the root apex upon exposure to Al. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
Ataxia telangiectasia-mutated and RAD3-related (ATR); FUNCTIONS IN: protein serine/threonine kinase activity, inositol or phosphatidylinositol kinase activity, binding, phosphotransferase activity, alcohol group as acceptor; INVOLVED IN: in 9 processes; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), UME (InterPro:IPR012993), Protein kinase-like domain (InterPro:IPR011009), PIK-related kinase, FAT (InterPro:IPR003151), Armadillo-type fold (InterPro:IPR016024), PIK-related kinase (InterPro:IPR014009), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), PIK-related kinase, FATC (InterPro:IPR003152); BEST Arabidopsis thaliana protein match is: ataxia-telangiectasia mutated (TAIR:AT3G48190.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:16343860..16353847 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 302383.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 7.04 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | 0.00 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 2702 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MAKDDNNLSS LVHELRERVA ASASTPANNL RHSSGDEDAL EIRFRAVIPN LLNTYVVPSL GNGREVTAVL KLVGHTARNI PGVFYHGTPS AILPVIARII 0101: PFFAEPEFVP GHGVLLETVG SLLMLLRSNS RKAYRIFFHD ALQAIQDMQP IASLHSIEPE VCESHIPFRC FCMSFSGIGG DLPDANKPRD GDGLVLNLLG 0201: ANRWQPFATC ILKLICKCLT EGTLYVQGLI HTSFFKAACS LVCCGGADVQ MACFEFATLV GSILTFNILP HVALIQSIIL LLSADEGLPV YRNTIYDSTI 0301: GRFLTAVYSS CSDAAVKLTA ESLVLVLSHA LQRTKSEELK ASLCSAYVRI VKSCPPCIWK IHCLLELLHL PEPCFQLIEC FKAVLIVLGP GCVRVETTKC 0401: GSHTSATSDR PVQGINAGKK RHIEDESTYK RKRQKVGDDI RRGVYFAPEF ADETDGKDAA SLREMLISTV ESLKPPPAGP SLSQTESSIV ALSMLTNAFC 0501: FCPWTDMTHR LFNQMYAWIP WIAGQVEETN PIMFDISIYL EGIHNLLLVG VDPQYEYTSK GNDLVAIQFL LKLPWTHYML FKTPSSLVKS KCLSVGIWTK 0601: LGLQDGSDFD IFSWSLSDDF EQVQAVAAIS MPLKVLFSGL GALLHMFPKL EHLLEEKELM IKKAIPQSLG FLSCLYGSST TDSEKTACHL LLHEDLKKDE 0701: TLNSLLQGFR CSKCDKFIER EDEKHFRIIE TPEMVKLKMD HHRDYFNLQS LYFNLLYDES SEETQLACVE VIRRILGHTS PDILVRTRSQ WIRCLQYLLV 0801: HVNTDVREAF CAQIGIFVQH PIVSCLFLSE DATEKSCERN FFNLIEHSLA AAKDLLVIQT LLETTAEVMV AVDVTSELFL ICLFLLIDQL DHPNLIVRIN 0901: ASKLINRSCY IHVKGGFATL LSTASHIQNE LFDNLSVRLT SRPNVVREFA EAVLGVETEE LVRKMVPAVL PKLLVYWQEN AQAANTLNEL AKLIDTDVVP 1001: LIVNWLPRVL AFALNQEEDK NLLSVLQLYH SQIGSDNQEI FAAALPALLD ELVCFVDIAD TPETDRRLQR LPDAIKKISK VLTNAEDLPG FLQNHFVGLL 1101: NSIDRKMLHA DDIFLQKQAL KRIKLLIEMM GHYLSTYVPK LMVLLMHAIE KDALQSEGLL VLHFFTRKLA DVSPSSIKYV ISQIFAALIP FLEKEKEGPH 1201: VYLDEVVKIL EELVLKNRDI VKEHICEFPL LPSIPSLGEL NNAIQEARGL MSLKDQLRDI VNGMKHENLN VRYMVACELS KLLYNRNEDV AALIAGELVS 1301: DMEILSSLIT YLLQGCAEES RTTVGQRLKL VCADCLGAIG AIDPAKVRVA SCSRFKIQCS DDDLIFELIH KHLARAFRAA QDTIIQDSAA LAIQELLKIA 1401: GCEPSLAGNV VVLTPQEHVQ VNVSGSRRCG GNNEVKDRGQ KLWDRFSNYV KELIAPCLTS RFQLPNVSDP GSAGPIYRPS MSFRRWLSYW IRKLTAFATG 1501: SRVSIFAACR GIVRHDMQTA TYLLPYLVLD VVCHGTEAAR LSISEEILSV LDAAASENSG VTINSFGVGQ SEVCVQAVFT LLDNLGQWVD DVKQGVALSS 1601: SLQSSGGRQV APKSKDQVSN STTEQDHLLV QCKYVLELLL AIPKVTLARA SFRCQAYARS LMYLESHVRG KSGSLNPAAE KTGIFENADV SSLMGIYSCL 1701: DEPDGLSGFA SLSKSLNLQD QLLINKKSGN WADVFTACEQ ALQMEPTSVQ RHSDVLNCLL NMCHHQTMVT HVDGLISRVP EYKKTWCTQG VQAAWRLGKW 1801: DLMDEYLDGA DAEGLLFSSS DSNASFDRDV AKILHAMMKK DQYSVAEGIA ISKQALIAPL AAAGMDSYTR AYPFVVKLHL LRELEDFQAV LNGDSYLEKS 1901: FSTSDQVFSK AVDNWENRLR FTQSSLWTRE PLLAFRRLVF GASGLGAQVG NCWLQYAKLC RLAGHYETAH RAILEAQASG APNVHMEKAK LLWITKRSDS 2001: AIIELQQSLL NMPEGVVDST VISSINSLLM APPNPEPTVR NTQSFKEKKD VAKTLLLYSK WIHHSGQKQK KDVLNLYTQV KELLPWEKGY FHLAKYYDEL 2101: YVDARKCQQE SSVFSSAGSK KGSVSSNLST EKAGWDYLFK GMYFYAKALH SGHKNLFQAL PRLLTLWFDF GTIYKTSGSA GNKELKSTHM KIMSLMRGCL 2201: KDLPTYQWLT VLPQLVSRIC HQNADTVLMV KNIITSVLHQ FPQQGLWIMA AVSKSTVPAR REAAAEIIQG ARKGFNQSDR GHNLFIQFAS LTDHFIKLCF 2301: HGGQPRSKVI NIATEFSALK RMMPLDIIMP IQQSLTISLP AFHMNNNERH SASVFSGSDL PTISGIADEA EILSSLQRPK KIILLGNDGI EYPFLCKPKD 2401: DLRKDARMME FTAMINRLLS KYPESRRRKL YIRTFAVAPL TEDCGLVEWV PHTRGLRHIL QDIYISCGKF DRQKTNPQIK RIYDQCAVKK EYEMLKTKIL 2501: PMFPPVFHKW FLTTFSEPAA WFRSRVAYAH TTAVWSMVGH IVGLGDRHGE NILFDSTSGD CVHVDFSCLF DKGLQLEKPE LVPFRLTQNM IDGLGITGYE 2601: GIFMRVCEIT LTVLRTHRET LMSILETFIH DPLVEWTKSH KSSGVEVQNP HAQRAISSIE ARLQGVVVGV PLPVEGQARR LIADAVSLEN LGKMYIWWMP 2701: WF |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)