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AT1G74310.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 1.000
ASURE: cytosol
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:31911558 (2020): mitochondrion
  • PMID:31615849 (2019): plastid plastid thylakoid
  • PMID:30962257 (2019): plastid
  • PMID:30783145 (2019): extracellular region plant-type cell wall
  • PMID:24361574 (2014): plastid plastid stroma
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:23673981 (2013): plastid plastid stroma plastoglobules
  • PMID:20061580 (2010): plastid plastid envelope
  • PMID:20061580 (2010): plastid plastid stroma
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : heat shock protein 101
Curator
Summary (TAIR10)
Encodes ClpB1, which belongs to the Casein lytic proteinase/heat shock protein 100 (Clp/Hsp100) family. Involved in refolding of proteins which form aggregates under heat stress. Also known as AtHsp101. AtHsp101 is a cytosolic heat shock protein required for acclimation to high temperature.
Computational
Description (TAIR10)
heat shock protein 101 (HSP101); FUNCTIONS IN: protein binding, ATPase activity, ATP binding; INVOLVED IN: response to high light intensity, response to hydrogen peroxide, response to heat, protein unfolding; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Clp ATPase, C-terminal (InterPro:IPR019489), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-2 (InterPro:IPR013093), ATPase, AAA-type, core (InterPro:IPR003959), Chaperonin clpA/B (InterPro:IPR001270), Chaperonin ClpA/B, conserved site (InterPro:IPR018368), Clp, N-terminal (InterPro:IPR004176); BEST Arabidopsis thaliana protein match is: casein lytic proteinase B2 (TAIR:AT4G14670.1); Has 27671 Blast hits to 24472 proteins in 3146 species: Archae - 360; Bacteria - 17866; Metazoa - 1124; Fungi - 430; Plants - 707; Viruses - 13; Other Eukaryotes - 7171 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT1G74310-MONOMERBioGrid:28990eggNOG:COG0542eggNOG:KOG1051
EMBL:AC020579EMBL:AF218796EMBL:AY062596EMBL:CP002684
EMBL:U13949EnsemblPlants:AT1G74310EnsemblPlants:AT1G74310.1entrez:843771
Gene3D:1.10.1780.10Gene3D:3.40.50.300GeneID:843771Genevisible:P42730
GO:GO:0005524GO:GO:0005634GO:GO:0005829GO:GO:0009408
GO:GO:0009570GO:GO:0009644GO:GO:0009941GO:GO:0019538
GO:GO:0042542GO:GO:0043335GO:GO:0045727Gramene:AT1G74310.1
hmmpanther:PTHR11638hmmpanther:PTHR11638:SF116HOGENOM:HOG000218211InParanoid:P42730
IntAct:P42730InterPro:IPR001270InterPro:IPR003593InterPro:IPR003959
InterPro:IPR004176InterPro:IPR018368InterPro:IPR019489InterPro:IPR027417
InterPro:IPR028299KEGG:ath:AT1G74310KO:K03695ncoils:Coil
OMA:DSQISDCPaxDb:P42730Pfam:P42730Pfam:PF00004
Pfam:PF02861Pfam:PF07724Pfam:PF10431PhylomeDB:P42730
PIR:F96771PRIDE:P42730PRINTS:PR00300PRO:PR:P42730
PROSITE:PS00870PROSITE:PS00871ProteinModelPortal:P42730Proteomes:UP000006548
RefSeq:NP_565083.1scanprosite:PS00870scanprosite:PS00871SMART:SM00382
SMART:SM01086SMR:P42730STRING:3702.AT1G74310.1SUPFAM:SSF52540
SUPFAM:SSF81923TAIR:AT1G74310tair10-symbols:ATHSP101tair10-symbols:HOT1
tair10-symbols:HSP101UniGene:At.48370UniGene:At.69978UniProt:P42730
Coordinates (TAIR10) chr1:-:27936715..27939862
Molecular Weight (calculated) 101301.00 Da
IEP (calculated) 6.00
GRAVY (calculated) -0.39
Length 911 amino acids
Sequence (TAIR10)
(BLAST)
001: MNPEKFTHKT NETIATAHEL AVNAGHAQFT PLHLAGALIS DPTGIFPQAI SSAGGENAAQ SAERVINQAL KKLPSQSPPP DDIPASSSLI KVIRRAQAAQ
101: KSRGDTHLAV DQLIMGLLED SQIRDLLNEV GVATARVKSE VEKLRGKEGK KVESASGDTN FQALKTYGRD LVEQAGKLDP VIGRDEEIRR VVRILSRRTK
201: NNPVLIGEPG VGKTAVVEGL AQRIVKGDVP NSLTDVRLIS LDMGALVAGA KYRGEFEERL KSVLKEVEDA EGKVILFIDE IHLVLGAGKT EGSMDAANLF
301: KPMLARGQLR CIGATTLEEY RKYVEKDAAF ERRFQQVYVA EPSVPDTISI LRGLKEKYEG HHGVRIQDRA LINAAQLSAR YITGRHLPDK AIDLVDEACA
401: NVRVQLDSQP EEIDNLERKR MQLEIELHAL EREKDKASKA RLIEVRKELD DLRDKLQPLT MKYRKEKERI DEIRRLKQKR EELMFSLQEA ERRYDLARAA
501: DLRYGAIQEV ESAIAQLEGT SSEENVMLTE NVGPEHIAEV VSRWTGIPVT RLGQNEKERL IGLADRLHKR VVGQNQAVNA VSEAILRSRA GLGRPQQPTG
601: SFLFLGPTGV GKTELAKALA EQLFDDENLL VRIDMSEYME QHSVSRLIGA PPGYVGHEEG GQLTEAVRRR PYCVILFDEV EKAHVAVFNT LLQVLDDGRL
701: TDGQGRTVDF RNSVIIMTSN LGAEHLLAGL TGKVTMEVAR DCVMREVRKH FRPELLNRLD EIVVFDPLSH DQLRKVARLQ MKDVAVRLAE RGVALAVTDA
801: ALDYILAESY DPVYGARPIR RWMEKKVVTE LSKMVVREEI DENSTVYIDA GAGDLVYRVE SGGLVDASTG KKSDVLIHIA NGPKRSDAAQ AVKKMRIEEI
901: EDDDNEEMIE D
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)