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AT4G23570.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
cytosol 0.988
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : phosphatase-related
Curator
Summary (TAIR10)
Closely related to SGT1B, may function in SCF(TIR1) mediated protein degradation. AtSGT1a and AtSGT1b are functionally redundant in the resistance to pathogenes. AtSGT1b was more highly expressed than AtSGT1. The N-terminal TPR domain of AtSGT1a reduces the steady-state level of Arabidopsis SGT1 proteins whereas the same domain from AtSGT1b enhances SGT1 accumulation. The TPR domain is dispensable for SGT1 resistance. AtSGT1a is induced upon pathogen infection and can function in R gene-mediated resistance.
Computational
Description (TAIR10)
SGT1A; FUNCTIONS IN: protein binding; INVOLVED IN: defense response, ubiquitin-dependent protein catabolic process, embryo development ending in seed dormancy; LOCATED IN: SCF ubiquitin ligase complex, nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), SGS (InterPro:IPR007699), HSP20-like chaperone (InterPro:IPR008978), CS domain (InterPro:IPR017447), CS-like domain (InterPro:IPR007052), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: phosphatase-related (TAIR:AT4G11260.1); Has 12440 Blast hits to 8629 proteins in 714 species: Archae - 442; Bacteria - 3949; Metazoa - 2875; Fungi - 1120; Plants - 1288; Viruses - 0; Other Eukaryotes - 2766 (source: NCBI BLink).
Protein Annotations
BioGrid:13746eggNOG:COG5091eggNOG:KOG0376eggNOG:KOG1309
EMBL:AF439975EMBL:AJ318020EMBL:AL035394EMBL:AL161559
EMBL:AY063978EMBL:AY096395EMBL:CP002687EnsemblPlants:AT4G23570
EnsemblPlants:AT4G23570.1EnsemblPlants:AT4G23570.2entrez:828457EvolutionaryTrace:Q9SUR9
Gene3D:1.25.40.10Gene3D:2.60.40.790GeneID:828457Genevisible:Q9SUR9
GO:GO:0005634GO:GO:0006511GO:GO:0006952GO:GO:0019005
GO:GO:0045087GO:GO:0071365GO:GO:2000072hmmpanther:PTHR22904
hmmpanther:PTHR22904:SF344HOGENOM:HOG000248210InParanoid:Q9SUR9IntAct:Q9SUR9
InterPro:IPR007052InterPro:IPR007699InterPro:IPR008978InterPro:IPR011990
InterPro:IPR013026InterPro:IPR019734iPTMnet:Q9SUR9KEGG:ath:AT4G23570
KO:K12795MINT:MINT-232436OMA:KRCEEMMPaxDb:Q9SUR9
PDB:2JKIPDB:2XCMPDBsum:2JKIPDBsum:2XCM
Pfam:PF04969Pfam:PF05002Pfam:PF13181Pfam:PF13414
Pfam:Q9SUR9Pfscan:PS50005Pfscan:PS50293Pfscan:PS51048
Pfscan:PS51203PhylomeDB:Q9SUR9PIR:T05589PRIDE:Q9SUR9
PRO:PR:Q9SUR9PROSITE:PS50005PROSITE:PS50293PROSITE:PS51048
PROSITE:PS51203ProteinModelPortal:Q9SUR9Proteomes:UP000006548Reactome:R-ATH-844456
RefSeq:NP_001031704.1RefSeq:NP_194088.1RefSeq:NP_849429.1SMART:SM00028
SMR:Q9SUR9STRING:3702.AT4G23570.3SUPFAM:SSF48452SUPFAM:SSF49764
TAIR:AT4G23570tair10-symbols:SGT1AUniGene:At.27360UniProt:Q9SUR9
Coordinates (TAIR10) chr4:+:12300015..12302493
Molecular Weight (calculated) 39226.50 Da
IEP (calculated) 4.65
GRAVY (calculated) -0.47
Length 350 amino acids
Sequence (TAIR10)
(BLAST)
001: MAKELADKAK EAFVDDDFDV AVDLYSKAID LDPNCAEFFA DRAQAYIKLE SFTEAVADAN KAIELDPSLT KAYLRKGTAC MKLEEYRTAK TALEKGASIT
101: PSESKFKKLI DECNFLITEE EKDLVQPVPS TLPSSVTAPP VSELDVTPTA KYRHEYYQKP EEVVVTVFAK GIPKQNVNID FGEQILSVVI EVPGEDAYYL
201: QPRLFGKIIP DKCKYEVLST KIEICLAKAD IITWASLEHG KGPAVLPKPN VSSEVSQRPA YPSSKKVKDW DKLEAEVKKQ EKDEKLEGDA ALNKFFREIY
301: QNADEDMRRA MSKSFVESNG TVLSTNWQEV GTKTIESTPP DGMELKKWEI
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)