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AT3G51770.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : tetratricopeptide repeat (TPR)-containing protein
Curator
Summary (TAIR10)
Encodes a negative regulator of 1-aminocyclopropane-1-carboxylic acid synthase5(ACS5), which catalyze the rate-limiting step in ethylene biosynthesis. ETO1 directly interacts with ACS5 and inhibits its enzyme activity and targets it for degradation via proteasome-dependent pathway. It also interacts with CUL3 (a component of ubiquitin ligase complexes). eto1 (and eto3) mutations elevate ethylene biosynthesis by affecting the posttranscriptional regulation of ACS
Computational
Description (TAIR10)
ETHYLENE OVERPRODUCER 1 (ETO1); CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), BTB/POZ fold (InterPro:IPR011333), BTB/POZ-like (InterPro:IPR000210), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: ETO1-like 2 (TAIR:AT5G58550.1); Has 1321 Blast hits to 1075 proteins in 262 species: Archae - 34; Bacteria - 623; Metazoa - 134; Fungi - 2; Plants - 202; Viruses - 0; Other Eukaryotes - 326 (source: NCBI BLink).
Protein Annotations
BioGrid:9658eggNOG:ENOG410II32eggNOG:ENOG410ZP3VEMBL:AF049236
EMBL:AY572791EMBL:CP002686EnsemblPlants:AT3G51770EnsemblPlants:AT3G51770.1
entrez:824340ExpressionAtlas:O65020Gene3D:1.25.40.10GeneID:824340
Genevisible:O65020GO:GO:0005622GO:GO:0009873GO:GO:0016567
Gramene:AT3G51770.1hmmpanther:PTHR23083hmmpanther:PTHR23083:SF420HOGENOM:HOG000242159
InParanoid:O65020IntAct:O65020InterPro:IPR000210InterPro:IPR011333
InterPro:IPR011990InterPro:IPR019734ncoils:CoilPaxDb:O65020
Pfam:O65020Pfam:PF00515Pfam:PF13181Pfam:PF13414
Pfscan:PS50005PhylomeDB:O65020PIR:T51148PRIDE:O65020
PRO:PR:O65020PROSITE:PS50005ProteinModelPortal:O65020Proteomes:UP000006548
RefSeq:NP_190745.6SMART:SM00028SMART:SM00225SMR:O65020
STRING:3702.AT3G51770.2SUPFAM:SSF48452SUPFAM:SSF54695TAIR:AT3G51770
tair10-symbols:ATEOL1tair10-symbols:ETO1UniGene:At.35356UniPathway:UPA00143
UniProt:O65020
Coordinates (TAIR10) chr3:-:19200328..19203974
Molecular Weight (calculated) 107032.00 Da
IEP (calculated) 6.30
GRAVY (calculated) -0.32
Length 951 amino acids
Sequence (TAIR10)
(BLAST)
001: MRSLKLAEGC KGTQVYALNP SAPTPPPPPG NSSSGGGGGG GSGGGTGGVG DKLLQHLSDH LRVNSVRSKS SRTYPPPTQP NAVVSPEFLL PCGLPVTDLL
101: EPQIDPCLKF VDLVEKMAQV YRRIENCSQF EKSGAYLEQC AIFRGISDPK LFRRSLRSSR QHAVDVHAKV VLASWLRFER REDELIGTTS MDCCGRNLEC
201: PKATLVSGYD PESVYDPCVC SGASRSEMMN EDECSTSQEV DYDMSFCIGD EEVRCVRYKI ASLSRPFKAM LYGGFREMKR ATINFTQNGI SVEGMRAAEI
301: FSRTNRLDNF PPNVVLELLK LANRFCCDEL KSACDSHLAH LVNSLDEAML LIEYGLEEAA YLLVAACLQV FLRELPSSMH NPNVIKIFCS AEGRERLASL
401: GHASFTLYFF LSQIAMEDDM KSNTTVMLLE RLVECAVDSW EKQLAYHQLG VVMLERKEYK DAQRWFNAAV EAGHLYSLVG VARTKFKRDH RYSAYKIINS
501: LISDHKATGW MHQERSLYCS GKEKLLDLDT ATEFDPTLTF PYKFRAVALV EENQFGAAIA ELNKILGFKA SPDCLEMRAW ISIGMEDYEG ALKDIRALLT
601: LEPNFMMFNW KIHGDHMVEL LRPLAQQWSQ ADCWMQLYDR WSSVDDIGSL AVVHHMLAND PGKSLLRFRQ SLLLLRLNCQ KAAMRSLRLA RNHSKSEHER
701: LVYEGWILYD TGHREEALAK AEESISIQRS FEAFFLKAYA LADSTLDPDS SNYVIQLLQE ALKCPSDGLR KGQALNNLGS VYVDCEKLDL AADCYTNALT
801: IKHTRAHQGL ARVYHLKNQR KAAYDEMTKL IEKAQNNASA YEKRSEYCDR EMAQSDLCLA TQLDPLRTYP YRYRAAVLMD DHKESEAIDE LSRAISFKPD
901: LQLLHLRAAF YDSMGEGASA IKDCEAALCI DPGHADTLEL YHKAREPNDQ K
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)