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AT2G18915.1
Subcellular Consensus
(Prediction and Experimental)

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SUBAcon:
nucleus 1.000
What is SUBAcon?
What is ASURE?
SUBAcon computations
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : LOV KELCH protein 2
Curator
Summary (TAIR10)
encodes a member of F-box proteins that includes two other proteins in Arabidopsis (ZTL and FKF1). These proteins contain a unique structure containing a PAS domain at their N-terminus, an F-box motif, and 6 kelch repeats at their C-terminus. Overexpression results in arrhythmic phenotypes for a number of circadian clock outputs in both constant light and constant darkness, long hypocotyls under multiple fluences of both red and blue light, and a loss of photoperiodic control of flowering time. Although this the expression of this gene itself is not regulated by circadian clock, it physically interacts with Dof transcription factors that are transcriptionally regulated by circadian rhythm. LKP2 interacts with Di19, CO/COL family proteins.
Computational
Description (TAIR10)
LOV KELCH protein 2 (LKP2); CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810), PAC motif (InterPro:IPR001610), Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 1 (InterPro:IPR006652), PAS fold (InterPro:IPR013767), PAS (InterPro:IPR000014), Kelch repeat type 2 (InterPro:IPR011498), Kelch-type beta propeller (InterPro:IPR015915); BEST Arabidopsis thaliana protein match is: Galactose oxidase/kelch repeat superfamily protein (TAIR:AT5G57360.1); Has 8615 Blast hits to 5462 proteins in 811 species: Archae - 85; Bacteria - 1957; Metazoa - 2226; Fungi - 909; Plants - 2075; Viruses - 0; Other Eukaryotes - 1363 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT2G18915EnsemblPlants:AT2G18915.1entrez:816408hmmpanther:PTHR23244hmmpanther:PTHR23244:SF322Pfam:PF07646Pfam:PF12937
Pfam:PF13415Pfam:PF13418Pfam:PF13426Pfscan:PS50112SUPFAM:0047741tair10-symbols:ADO2tair10-symbols:LKP2
TIGRfam:TIGR00229
Coordinates (TAIR10) chr2:-:8194792..8197255
Molecular Weight (calculated) 65119.70 Da
IEP (calculated) 4.79
GRAVY (calculated) -0.08
Length 601 amino acids
Sequence (TAIR10)
(BLAST)
001: MQNQMEWDSD SDLSGGDEVA EDGWFGGDNG AIPFPVGSLP GTAPCGFVVS DALEPDNPII YVNTVFEIVT GYRAEEVIGP FTKRRHPMVD STIVAKMRQC
101: LENGIEFQGE LLNFRKDGSP LMNKLRLVPI REEDEITHFI GVLLFTDAKI DLGPSPDLSA KEIPRISRSF TSALPIGERN VSRGLCGIFE LSDEVIAIKI
201: LSQLTPGDIA SVGCVCRRLN ELTKNDDVWR MVCQNTWGTE ATRVLESVPG AKRIGWVRLA REFTTHEATA WRKFSVGGTV EPSRCNFSAC AVGNRIVIFG
301: GEGVNMQPMN DTFVLDLGSS SPEWKSVLVS SPPPGRWGHT LSCVNGSRLV VFGGYGSHGL LNDVFLLDLD ADPPSWREVS GLAPPIPRSW HSSCTLDGTK
401: LIVSGGCADS GALLSDTFLL DLSMDIPAWR EIPVPWTPPS RLGHTLTVYG DRKILMFGGL AKNGTLRFRS NDVYTMDLSE DEPSWRPVIG YGSSLPGGMA
501: APPPRLDHVA ISLPGGRILI FGGSVAGLDS ASQLYLLDPN EEKPAWRILN VQGGPPRFAW GHTTCVVGGT RLVVLGGQTG EEWMLNEAHE LLLATSTTAS
601: T
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)