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AT4G13350.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
cytosol 0.500
nucleus 0.500
ASURE: cytosol,nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : NSP (nuclear shuttle protein)-interacting GTPase
Curator
Summary (TAIR10)
Encodes a GTPase that interacts with nuclear shuttle proteins (NSPs) from a number of different plant viruses. The gene is widely expressed and NIG transcript levels do not rise in response to viral infection. This cytoplasmic protein does not directly interact with a viral movement protein (MP), but, it does promote the movement of NSP from the nucleus to the cytoplasm. Overexpression of NIG in Arabidopsis plants renders them more sensitive to geminivirus infection.
Computational
Description (TAIR10)
NSP (nuclear shuttle protein)-interacting GTPase (NIG); FUNCTIONS IN: GTP binding, GTPase activity; INVOLVED IN: nucleocytoplasmic transport, response to virus; LOCATED IN: cytosol, cytoplasm; EXPRESSED IN: flower, root, cultured cell, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164); BEST Arabidopsis thaliana protein match is: ArfGap/RecO-like zinc finger domain-containing protein (TAIR:AT4G32630.1); Has 7463 Blast hits to 6530 proteins in 396 species: Archae - 2; Bacteria - 285; Metazoa - 3343; Fungi - 1586; Plants - 848; Viruses - 60; Other Eukaryotes - 1339 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT4G13350-MONOMEReggNOG:ENOG410IUM9eggNOG:ENOG4111QGHEMBL:AY062505
EMBL:BT008379EMBL:CP002687EnsemblPlants:AT4G13350EnsemblPlants:AT4G13350.1
EnsemblPlants:AT4G13350.2entrez:826966GeneID:826966GO:GO:0003924
GO:GO:0005096GO:GO:0005525GO:GO:0005737GO:GO:0005829
GO:GO:0006913GO:GO:0009615Gramene:AT4G13350.1Gramene:AT4G13350.2
hmmpanther:PTHR23180hmmpanther:PTHR23180:SF200HOGENOM:HOG000064627InterPro:IPR001164
KEGG:ath:AT4G13350OMA:MQQVPNMPfam:PF01412Pfscan:PS50115
PhylomeDB:Q8W4K6PRINTS:PR00405PROSITE:PS50115Proteomes:UP000006548
RefSeq:NP_193071.2RefSeq:NP_849540.1SMART:SM00105SMR:Q8W4K6
STRING:3702.AT4G13350.1SUPFAM:SSF57863TAIR:AT4G13350tair10-symbols:NIG
UniGene:At.23435UniProt:Q8W4K6
Coordinates (TAIR10) chr4:-:7770170..7773321
Molecular Weight (calculated) 65030.30 Da
IEP (calculated) 7.37
GRAVY (calculated) -0.75
Length 602 amino acids
Sequence (TAIR10)
(BLAST)
001: MAGRVKEDEK NEKIIRSLLK LPENKRCINC NSLGPQYVCT TFWTFVCTNC SGIHREFTHR VKSISMAKFT SQEVTALKEG GNQHAKDIYF KGLDQQRQSV
101: PDGSNVERLR DFIRHVYVNK RYTNEKNDDK SPSETRSSSG SRSPPYEDGY DRRYGDRSSP GGRSPGFETG SRNAVNNRKS PARPEILNDW RREDRFGGRK
201: TSEEGSQSPE QVKDLGSASP PVARPVREIL GDSVIPLRVG EPPKPPVSRN TDASAHAKSG TSLSSLMSTN EKPPEVKLET ALSLIDFDTD FETPAPSVAI
301: QAPLSTTSQP APQPTTSSND NWASFDAAPS APSLNVSQPP PSGNTLDSLL SQLAVTSSVP GQASTPSNGP VNLGHSTSQI FAPFQNEHSS EQPWNTALAS
401: NVQRSMSAPS LQPLQGVPSG GLQSSEVKPS GRSELPADLF AVNYPSYHAP VPGWQAGPPH AMHYGMQQYN NPVPYQNVPQ PGKSMNPFDF SPGPPSQTQT
501: ENMFPSMAPL QGALPPSGMM PSQGVHNQFN IPSQGSAHPS AMPPRYMPSQ IPGSMPPSNV NPIGDINTSY DTQQTYQNFG SSFAAAVPLN PPSFQSGGNP
601: FG
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)