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AT3G13080.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
vacuole 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:25641898 (2015): plasma membrane
  • PMID:23903016 (2013): plant-type vacuole plant-type vacuole membrane
  • PMID:22923678 (2012): plant-type vacuole
  • PMID:22550958 (2012): plastid
  • PMID:21988472 (2012): plant-type vacuole plant-type vacuole membrane
  • PMID:21433285 (2011): plasma membrane
  • PMID:17151019 (2007): plant-type vacuole
  • PMID:16618929 (2006): plant-type vacuole
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : multidrug resistance-associated protein 3
Curator
Summary (TAIR10)
encodes an ATP-dependent MRP-like ABC transporter able to transport glutathione-conjugates as well as chlorophyll catabolites. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.
Computational
Description (TAIR10)
multidrug resistance-associated protein 3 (MRP3); FUNCTIONS IN: chlorophyll catabolite transmembrane transporter activity, ATPase activity, coupled to transmembrane movement of substances, glutathione S-conjugate-exporting ATPase activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: apoplast, vacuolar membrane, plasma membrane, plant-type vacuole; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 8 (TAIR:AT3G13090.1); Has 627889 Blast hits to 345635 proteins in 4027 species: Archae - 11144; Bacteria - 511144; Metazoa - 11505; Fungi - 7381; Plants - 6155; Viruses - 9; Other Eukaryotes - 80551 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G13080-MONOMERBioCyc:ARA:GQT-1977-MONOMERBioCyc:ARA:GQT-1978-MONOMERBioCyc:ARA:GQT-1979-MONOMER
EC:3.6.3.44eggNOG:COG1132eggNOG:KOG0054EMBL:AP000375
EMBL:CP002686EMBL:U92650EnsemblPlants:AT3G13080EnsemblPlants:AT3G13080.1
entrez:820496ExpressionAtlas:Q9LK64Gene3D:3.40.50.300GeneID:820496
Genevisible:Q9LK64GO:GO:0000325GO:GO:0005524GO:GO:0005773
GO:GO:0005774GO:GO:0008559GO:GO:0009506GO:GO:0010290
GO:GO:0015431GO:GO:0016021GO:GO:0042626GO:GO:0048046
hmmpanther:PTHR24223hmmpanther:PTHR24223:SF181InParanoid:Q9LK64InterPro:IPR003439
InterPro:IPR003593InterPro:IPR011527InterPro:IPR017871InterPro:IPR027417
KEGG:ath:AT3G13080OMA:RIGNFSWPaxDb:Q9LK64Pfam:PF00005
Pfam:PF00664Pfam:Q9LK64Pfscan:PS50893Pfscan:PS50929
PhylomeDB:Q9LK64PIR:T52081PRIDE:Q9LK64PRO:PR:Q9LK64
PROSITE:PS00211PROSITE:PS50893PROSITE:PS50929ProteinModelPortal:Q9LK64
Proteomes:UP000006548Reactome:R-ATH-382556RefSeq:NP_187915.1RefSeq:NP_850575.1
scanprosite:PS00211SMART:SM00382SMR:Q9LK64STRING:3702.AT3G13080.1
SUPFAM:SSF52540SUPFAM:SSF90123TAIR:AT3G13080tair10-symbols:ABCC3
tair10-symbols:ATMRP3tair10-symbols:MRP3TCDB:3.A.1.208.17TMHMM:TMhelix
UniGene:At.20479UniProt:Q9LK64
Coordinates (TAIR10) chr3:-:4196019..4201250
Molecular Weight (calculated) 168980.00 Da
IEP (calculated) 6.29
GRAVY (calculated) 0.18
Length 1514 amino acids
Sequence (TAIR10)
(BLAST)
0001: MDFLGSTTGS GTLAMLFSFS ESILPLDSRS FLLKPLFLRW LSGFLHSVLL LVLFFSWVRK KIRGDSGVTE SLKDRRDFGF KSALFCSLAL SLLNLVLMSL
0101: SGFYWYESGW LDNEQLVSSL GFLLGMVSWG VLSICLHRCR DCEHKKAPFL LRLWLVFYLV VSCYSLVVDF VMYERRETVP VHLLVFDIVA FIAAVFLGYV
0201: AVLKKDRSNS NGVLEEPLLN GGDSRVGGDD SVELNKTNGS GEATPYSRAG ILSLLTFSWM SPLIDIGNKK TLDLEDVPQL HDTDSVVGLA PKFRSMLESP
0301: DGGERSGVTT FKLIKALYFT AQWEILVTAF FAFIYTVASY VGPALIDTFV QYLNGRRQYN HEGYVLVITF FAAKIVECLS QRHWFFRLQK VGIRMRSALV
0401: AMIYEKGLTL SCQSKQGRTS GEIINFMTVD AERIGNFSWY MHDPWMVLLQ VGLALWILYR NLGLASIAAL VATIIVMLIN FPFGRMQERF QEKLMEAKDS
0501: RMKSTSEILR NMRILKLQGW EMKFLSKIFD LRKSEEGWLK KYVYNSAVIS FVFWGAPTLV SVSTFGACIL LGIPLESGKI LSALATFRIL QEPIYNLPDT
0601: ISMIVQTKVS LDRLASYLCL DNLQPDIVER LPKGSSDVAV EVINSTLSWD VSSSNPTLKD INFKVFPGMK VAVCGTVGSG KSSLLSSLLG EVPKVSGSLK
0701: VCGTKAYVAQ SPWIQSGKIE DNILFGKPME RERYDKVLEA CSLSKDLEIL SFGDQTVIGE RGINLSGGQK QRIQIARALY QDADIYLFDD PFSAVDAHTG
0801: SHLFKEVLLG LLCSKSVIYV THQVEFLPAA DLILVMKDGR ISQAGKYNDI LNSGTDFMEL IGAHQEALAV VDSVDANSVS EKSALGQENV IVKDAIAVDE
0901: KLESQDLKND KLESVEPQRQ IIQEEEREKG SVALDVYWKY ITLAYGGALV PFILLGQVLF QLLQIGSNYW MAWATPVSED VQAPVKLSTL MIVYVALAFG
1001: SSLCILLRAT LLVTAGYKTA TELFHKMHHC IFRSPMSFFD STPSGRIMSR ASTDQSAVDL ELPYQFGSVA ITVIQLIGII GVMSQVSWLV FLVFIPVVAA
1101: SIWYQRYYIA AARELSRLVG VCKAPLIQHF SETISGATTI RSFSQEFRFR SDNMRLSDGY SRPKFYTAGA MEWLCFRLDM LSSLTFVFSL VFLVSIPTGV
1201: IDPSLAGLAV TYGLSLNTLQ AWLIWTLCNL ENKIISVERI LQYASVPSEP PLVIESNRPE QSWPSRGEVE IRDLQVRYAP HMPLVLRGIT CTFKGGLRTG
1301: IVGRTGSGKS TLIQTLFRIV EPSAGEIRID GVNILTIGLH DLRLRLSIIP QDPTMFEGTM RSNLDPLEEY TDDQIWEALD KCQLGDEVRK KEQKLDSSVS
1401: ENGDNWSMGQ RQLVCLGRVL LKRSKILVLD EATASVDTAT DNLIQKTLRE HFSDCTVITI AHRISSVIDS DMVLLLSNGI IEEYDTPVRL LEDKSSSFSK
1501: LVAEYTSRSS SSFD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)