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AT3G04810.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.886
ASURE: cytoskeleton
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : NIMA-related kinase 2
Curator
Summary (TAIR10)
Encodes AtNek2, a member of the NIMA-related serine/threonine kinases (Neks) that have been linked to cell-cycle regulation in fungi and mammals. Plant Neks might be involved in plant development processes.
Computational
Description (TAIR10)
NIMA-related kinase 2 (NEK2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NIMA-related kinase 3 (TAIR:AT5G28290.1); Has 124232 Blast hits to 122078 proteins in 4151 species: Archae - 113; Bacteria - 14232; Metazoa - 45825; Fungi - 12238; Plants - 30614; Viruses - 487; Other Eukaryotes - 20723 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:AT3G04810-MONOMERBioCyc:ARA:GQT-1414-MONOMEREC:2.7.11.1eggNOG:ENOG410Y7JF
eggNOG:KOG0589EMBL:AC009465EMBL:AF370162EMBL:BT000875
EMBL:CP002686EnsemblPlants:AT3G04810EnsemblPlants:AT3G04810.1EnsemblPlants:AT3G04810.2
entrez:819641GeneID:819641Genevisible:Q9CAU7GO:GO:0004674
GO:GO:0005524GO:GO:0006468Gramene:AT3G04810.1Gramene:AT3G04810.2
hmmpanther:PTHR24362hmmpanther:PTHR24362:SF255HOGENOM:HOG000238503InParanoid:Q9CAU7
InterPro:IPR000719InterPro:IPR008271InterPro:IPR011009InterPro:IPR017441
iPTMnet:Q9CAU7KEGG:ath:AT3G04810KO:K08857OMA:QDERYDE
PaxDb:Q9CAU7Pfam:PF00069Pfam:Q9CAU7Pfscan:PS50011
PhylomeDB:Q9CAU7PRIDE:Q9CAU7PRO:PR:Q9CAU7PROSITE:PS00107
PROSITE:PS00108PROSITE:PS50011ProteinModelPortal:Q9CAU7Proteomes:UP000006548
Reactome:R-ATH-179409RefSeq:NP_187132.1RefSeq:NP_974221.2scanprosite:PS00107
scanprosite:PS00108SMART:SM00220SMR:Q9CAU7SUPFAM:SSF56112
TAIR:AT3G04810tair10-symbols:ATNEK2tair10-symbols:NEK2UniGene:At.17651
UniGene:At.50988UniProt:Q9CAU7
Coordinates (TAIR10) chr3:+:1318096..1321101
Molecular Weight (calculated) 68038.50 Da
IEP (calculated) 9.96
GRAVY (calculated) -0.55
Length 606 amino acids
Sequence (TAIR10)
(BLAST)
001: MENYEVLEQI GKGSFGSALL VRHKHEKKLY VLKKIRLARQ TGRTRRSAHQ EMELISKIHN PFIVEYKDSW VEKGCYVCII IGYCKGGDMA EAIKKTNGVH
101: FTEEKLCKWL VQILLALEYL HANHILHRDV KCSNIFLTKD QDIRLGDFGL AKVLTSDDLA SSVVGTPSYM CPELLADIPY GSKSDIWSLG CCMYEMTAMK
201: PAFKAFDMQG LINRINRSIV PPLPAQYSAA FRGLVKSMLR KNPELRPSAA ELLRQPLLQP YIQKIHLKVN DPGSNVLPAQ WPESESARRN SFPEQRRRPA
301: GKSHSFGPSR FRGNLEDSVS SIKKTVPAYL NRERQVDLST DASGDGTVVR RTSEASKSSR YVPVRASASP VRPRQPRSDL GQLPVSSQLK NRKPAALIRR
401: ASMPSSRKPA KEIKDSLYIS KTSFLHQINS PDVSMNAPRI DKIEFPLASY EEEPFVPVVR GKKKKASSRG SYSPPPEPPL DCSITKDKFT LEPGQNREGA
501: IMKAVYEEDA YLEDRSESSD QNATAGASSR ASSGVRRQRF DPSSYQQRAE ALEGLLEFSA RLLQDERYDE LNVLLRPFGP GKVSPRETAI WLSKSFKETT
601: TTKLGD
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)