AT5G58220.3
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:cytosol 1.000 ASURE: cytosol What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : transthyretin-like protein | ||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a transthyretin-like S-allantoin synthase protein that catalyzes two steps in the allantoin biosynthesis pathway by acting as a hydroxyisourate hydrolase and a 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) decarboxylase. Two alternatively spliced versions of the transcript give rise to a longer peroxisomally-targeted protein (AT5G58220.1 (called TTL1-)) and a slightly shorter cytoplasmic protein (AT5G58220.3 (called TTL2-)). Both have roughly equivalent enzymatic activity in vitro, but, allantoin biosynthesis is believed to occur in the peroxisome suggesting that the cytosolic form may participate in a different process. | ||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
transthyretin-like protein (TTL); FUNCTIONS IN: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity, hydroxyisourate hydrolase activity; INVOLVED IN: regulation of cell growth by extracellular stimulus, brassinosteroid mediated signaling pathway, protein homotetramerization; LOCATED IN: cytosol, extrinsic to internal side of plasma membrane, peroxisome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Bifunctional hydroxyisourate hydrolase/2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (InterPro:IPR017129), Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (InterPro:IPR018020), Hydroxyisourate hydrolase (InterPro:IPR014306), Transthyretin/hydroxyisourate hydrolase (InterPro:IPR000895); Has 3236 Blast hits to 3236 proteins in 817 species: Archae - 6; Bacteria - 1906; Metazoa - 529; Fungi - 103; Plants - 58; Viruses - 0; Other Eukaryotes - 634 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:23554546..23555861 | ||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 34150.20 Da | ||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.31 | ||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.24 | ||||||||||||||||||||||||||||||||||||||||
| Length | 311 amino acids | ||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MAMEIGEDEW KVCCGSSEFA KQMSTSGPLT SQEAIYTARD IWFNQVNVTD WLEAFSAHPQ IGNTPSPSIN SDFARRSVSE QSTAFATTSA SALQELAEWN 101: VLYKKKFGFI FIICASGRTH AEMLHALKER YENRPIVELE IAAMEQMKIT ELRMAKLFSD KAKVISETDS SSSPVSTKPQ AEAKAPKRSR PPITTHVLDV 201: SRGAPAAGVE VHLEVWSGTT GPSFVHGGGG VWSSVGTSAT DRDGRSGPLM DLVDALNPGT YRISFDTAKY SPGCFFPYVS IVFQVTESQK WEHFHVPLLL 301: APFSFSTYRG S |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)