AT5G55390.1
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 ASURE: nucleus What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : ENHANCED DOWNY MILDEW 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes EDM2 (enhanced downy mildew 2). The predicted protein bears typical features of transcriptional regulators. EDM2 contains two putative bipartite nuclear localization signals (NLS) two zinc-finger-like motifs, a Proline-rich region and a large aspartic acid-rich region. Both zinc-finger-like stretches resemble the PHD (plant homeodomain) finger motif. Mutations in EDM2 comprise RPP7 mediated resistance against Hyaloperonospora parasitica isolate Hiks1 (HpHiks1). EDM2 may function as a direct or indirect regulator of RPP7 expression. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
ENHANCED DOWNY MILDEW 2 (EDM2); CONTAINS InterPro DOMAIN/s: Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011); BEST Arabidopsis thaliana protein match is: EDM2-like protein1 (TAIR:AT5G48090.1); Has 807 Blast hits to 790 proteins in 126 species: Archae - 0; Bacteria - 19; Metazoa - 421; Fungi - 75; Plants - 194; Viruses - 2; Other Eukaryotes - 96 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:22448152..22454414 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 146795.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.40 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.70 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 1297 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
0001: MTFVDDDEEE DFSVPQSASN YYFEDDDKEP VSFARLPIQW SVEEKVDGSG LGFYLRGRSD NGLLPLHKLV KAWRYDLSNF QPEISVLTKD NIWIKLEEPR 0101: KSYGELIRTV LVTLHSIQFL RRNPQASEKA LWEKLTRSLR SYDVKPSQND LVDHIGLIAE AAKRDRNLAN SKFILAFLTK KPTKRRLPDE DNAKDDFIVG 0201: DEDTYVASDE DELDDEDDDF FESVCAICDN GGEILCCEGS CLRSFHATKK DGEDSLCDSL GFNKMQVEAI QKYFCPNCEH KIHQCFICKN LGSSDNSSGA 0301: AEVFQCVSAT CGYFYHPHCV TRRLRLGNKE ESEALERQII AGEYTCPLHK CSVCENGEVK TDSNLQFAVC RRCPKSYHRK CLPREISFED IEDEDILTRA 0401: WDGLLHNRVL IYCQEHEIDE ELLTPVRDHV KFPFTEEQKV FVKEQRRILE SHVGRDKARL KVKDPALQDT CGKASKNSFR SSFPSSKDGF STKKHGLVSS 0501: VPDHSRKRKD IDPSIKHKMV PQKSQKMMED SREAGKNKLG VKEARDAGKS KISLGERLFS YTQEPNPVKP GRVIPVDSKH NKTDSIASKE PGSEIPTLDN 0601: DSQRRLLAVM KKATEEITMG TILKKFKIQS TMSTHSTRNV VDKTITMGKV EGSVQAIRTA LKKLEEGGNI EDAKAVCEPE VLSQILKWKD KLKVYLAPFL 0701: HGARYTSFGR HFTNPEKLQQ IVDRLHWYAD DGDMIVDFCC GSNDFSCLMN AKLEETGKKC LYKNYDLFPA KNNFNFERKD WMTVSKDELE PGSKLIMGLN 0801: PPFGVNASLA NKFITKALEF RPKILILIVP PETERLDKKK SSYVLIWEDK TFLSGNSFYL PGSVNEEDKQ LEDWNLVPPP LSLWSRSDFA AKHKKIAEKH 0901: CHLSRDVGSS KLKIVEEEAN ASLHPLGASD GMCDDIPMEK DELEVAECVN KILVSEKIDT VETVARVHQS DHLSRRSQLK KEGKTKDYSG RKLGKSMDSN 1001: NVDWKSNDME EDQGELSRAP ESIKVKIPEM TSDWQSPVRS SPDDIYAVCT SISTTTPQRS HEAVEASLPA ITRTKSNLGK NIREHGCKVQ GTGKPEVSRD 1101: RPSSVRTSRE DIYTVRPSPE NTGQKPFEAF EPSYGASLSH FDDGLAAKYG GFGGGYRMPD PPFLPDQFPL RNGPNEMFDF RGYSDLDRGI GQREYPQQYG 1201: GHLDPMLAPP PPPNLMDNAF PLQQRYAPHF DQMNYQRMSS FPPQPPLQPS GHNLLNPHDF PLPPPPPSDF EMSPRGFAPG PNPNYPYMSR SGGWIND |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)