AT5G45340.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:extracellular 0.891 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : cytochrome P450, family 707, subfamily A, polypeptide 3 | ||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein with ABA 8'-hydroxylase activity; involved in ABA catabolism. Mutant analyses show that disruption in the gene results in more drought tolerance whereas overexpression results in increased transpiration rate and reduced drought tolerance. Gene involved in postgermination growth. Plant P450 CYP707A3, ABA 8'-hydroxylase, binds enantioselectively (+)-ABA but not (-)-ABA, whereas the enzyme binds both enantiomers of AHI1 (a structural ABA analogue used as ABA 8'-hydroxylase competitive inhibitor). | ||||||||||||
| Computational Description (TAIR10) |
cytochrome P450, family 707, subfamily A, polypeptide 3 (CYP707A3); FUNCTIONS IN: oxygen binding, (+)-abscisic acid 8'-hydroxylase activity; INVOLVED IN: in 8 processes; LOCATED IN: endomembrane system; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 707, subfamily A, polypeptide 1 (TAIR:AT4G19230.2); Has 36434 Blast hits to 36316 proteins in 1856 species: Archae - 82; Bacteria - 8479; Metazoa - 11318; Fungi - 6149; Plants - 8238; Viruses - 6; Other Eukaryotes - 2162 (source: NCBI BLink). | ||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:18369121..18370909 | ||||||||||||
| Molecular Weight (calculated) | 50602.30 Da | ||||||||||||
| IEP (calculated) | 9.12 | ||||||||||||
| GRAVY (calculated) | -0.20 | ||||||||||||
| Length | 446 amino acids | ||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MDFSGLFLTL SAAALFLCLL RFIAGVRRSS STKLPLPPGT MGYPYVGETF QLYSQDPNVF FAAKQRRYGS VFKTHVLGCP CVMISSPEAA KFVLVTKSHL 101: FKPTFPASKE RMLGKQAIFF HQGDYHSKLR KLVLRAFMPD AIRNMVPHIE SIAQESLNSW DGTQLNTYQE MKTYTFNVAL ISILGKDEVY YREDLKRCYY 201: ILEKGYNSMP INLPGTLFHK AMKARKELAQ ILANILSKRR QNPSSHTDLL GSFMEDKAGL TDEQIADNII GVIFAARDTT ASVLTWILKY LADNPTVLEA 301: VTEEQMAIRK DKKEGESLTW EDTKKMPLTY RVIQETLRAA TILSFTFREA VEDVEYEGYL IPKGWKVLPL FRNIHHNADI FSDPGKFDPS RFEVAPKPNT 401: FMPFGSGIHS CPGNELAKLE ISVLIHHLTT KYRLVHLQND NSPFGN |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)