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AT5G41360.1
Subcellular Consensus
(Prediction and Experimental)
min: heatmap :max

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SUBAcon:
nucleus 1.000
ASURE: nucleus
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : homolog of Xeroderma pigmentosum complementation group B 2
Curator
Summary (TAIR10)
Encodes XPB2, a DNA repair protein and transcription factor. Arabidopsis thaliana has duplicated XPB gene (AtXPB1 and AtXPB2, with high similarity to each other). XPB proteins are involved in both DNA repair and transcription, they are component of the transcription factor IIH (TFIIH) and are responsible for DNA helicase activity during nucleotide (nt) excision repair (NER). Complementation assays in yeast rad25 mutant strains suggest the involvement of AtXPB2 in DNA repair. Although both genes are expressed in a constitutive manner during the plant life cycle, Northern blot analyses suggest that light modulates the expression level of both XPB copies.
Computational
Description (TAIR10)
homolog of Xeroderma pigmentosum complementation group B 2 (XPB2); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to UV-B, N-terminal protein myristoylation; EXPRESSED IN: whole plant; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), DEAD-like helicase, N-terminal (InterPro:IPR014001), Xeroderma pigmentosum group B protein (XP-B) (InterPro:IPR001161), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: homolog of xeroderma pigmentosum complementation group B 1 (TAIR:AT5G41370.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
Protein Annotations
BioCyc:ARA:GQT-574-MONOMERBioGrid:19389EC:3.6.4.12eggNOG:COG1061
eggNOG:KOG1123EMBL:AB006707EMBL:AF308595EMBL:AY550923
EMBL:CP002688EnsemblPlants:AT5G41360EnsemblPlants:AT5G41360.1entrez:834138
Gene3D:3.40.50.300GeneID:834138Genevisible:Q9FUG4GO:GO:0003677
GO:GO:0004003GO:GO:0005524GO:GO:0005634GO:GO:0006289
GO:GO:0006355GO:GO:0006367GO:GO:0010224Gramene:AT5G41360.1
hmmpanther:PTHR11274hmmpanther:PTHR11274:SF0HOGENOM:HOG000160172InParanoid:Q9FUG4
InterPro:IPR001161InterPro:IPR001650InterPro:IPR006935InterPro:IPR014001
InterPro:IPR027417InterPro:IPR032438InterPro:IPR032830KEGG:ath:AT5G41360
KO:K10843MINT:MINT-8066642OMA:YLRENTRPaxDb:Q9FUG4
Pfam:PF04851Pfam:PF13625Pfam:PF16203Pfam:Q9FUG4
Pfscan:PS51192Pfscan:PS51194PhylomeDB:Q9FUG4PIR:S71206
PRIDE:Q9FUG4PRO:PR:Q9FUG4PROSITE:PS51192PROSITE:PS51194
ProteinModelPortal:Q9FUG4Proteomes:UP000006548Reactome:R-ATH-113418Reactome:R-ATH-5696395
Reactome:R-ATH-5696400Reactome:R-ATH-674695Reactome:R-ATH-6781823Reactome:R-ATH-6782135
Reactome:R-ATH-6782210Reactome:R-ATH-72086Reactome:R-ATH-73776Reactome:R-ATH-73779
Reactome:R-ATH-75953Reactome:R-ATH-76042Reactome:R-ATH-77075RefSeq:NP_568591.1
SMART:SM00487SMART:SM00490SMR:Q9FUG4STRING:3702.AT5G41360.1
SUPFAM:SSF52540TAIR:AT5G41360tair10-symbols:ATXPB2tair10-symbols:XPB2
TIGRfam:TIGR00603TIGRFAMs:TIGR00603UniGene:At.24438UniProt:Q9FUG4
Coordinates (TAIR10) chr5:+:16544574..16549121
Molecular Weight (calculated) 86740.70 Da
IEP (calculated) 8.17
GRAVY (calculated) -0.54
Length 766 amino acids
Sequence (TAIR10)
(BLAST)
001: MGNDERKRPT KKMKYGGKDD QKMKNIQNVE DYYDDADEDS RDGEGEEKRR DFTDLELKPD HGNRPLWACA DGKIFLETFS PLYKQAYDFL IAIAEPVCRP
101: ESMHEYNLTP HSLYAAVSVG LETETIISVL NKLSKTKLPG EIIDFIHAST ANYGKVKLVL KKNRYFIESP FPEVLKRLLS DDVINRARFT SEPYYGGDGF
201: TIGKTSGELE AGPGELLNEA ELAAAAEEKE THSFEIDPAL VENVKQRCLP NALNYPMLEE YDFRNDNVNP DLDMELKPHA QPRPYQEKSL SKMFGNGRAR
301: SGIIVLPCGA GKSLVGVSAA ARIKKSCLCL ATNAVSVDQW AYQFKLWSTI KDDQICRFTS DSKERFRGNA GVVVTTYNMI AFGGKRSEEA EKIIEEMRNR
401: EWGLLLMDEV HVVPAHMFRK VISITKSHCK LGLTATLVRE DEKITDLNFL IGPKLYEANW LDLVKGGFIA NVQCAEVWCP MTKEFFAEYL KKENSKKKQA
501: LYVMNPNKFR ACEFLIRFHE QQRGDKIIVF ADNLFALTEY AMKLRKPMIY GATSHIERTK ILEAFKTSKT VNTVFLSKVG DNSIDIPEAN VIIQISSHAG
601: SRRQEAQRLG RILRAKGKLE DRMAGGKEEY NAFFYSLVST DTQEMYYSTK RQQFLIDQGY SFKVITSLPP PDAGSSLGYH SQEEQLSLLG KVLNAGDDMV
701: GLEQLEEDTD GKALKTRRSM GSMSAMSGAN GRVYMEYNSG RQKSGNQSKK PKDPTKRHNI FKKRYV
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)