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AT5G26780.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
mitochondrion 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : serine hydroxymethyltransferase 2
Curator
Summary (TAIR10)
Encodes a protein with serine hydroxymethyltransferase activity which is thought to be localized in the mitochondrial matrix. SHM2 expression fails to rescue the conditional lethal phenotype of the shm1-1 mutant, defective in SHM1.
Computational
Description (TAIR10)
serine hydroxymethyltransferase 2 (SHM2); FUNCTIONS IN: glycine hydroxymethyltransferase activity, cobalt ion binding, zinc ion binding; INVOLVED IN: glycine metabolic process, L-serine metabolic process; LOCATED IN: mitochondrion, mitochondrial respiratory chain complex I; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine transhydroxymethyltransferase 1 (TAIR:AT4G37930.1); Has 11607 Blast hits to 11584 proteins in 2835 species: Archae - 259; Bacteria - 6404; Metazoa - 333; Fungi - 289; Plants - 321; Viruses - 6; Other Eukaryotes - 3995 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT5G26780EnsemblPlants:AT5G26780.2entrez:832736gramene_pathway:2.1.2.1
gramene_pathway:GLYSYN2-PWYgramene_pathway:PWY-181gramene_pathway:PWY-2161gramene_pathway:PWY-2201
gramene_pathway:PWY-3841hmmpanther:PTHR11680hmmpanther:PTHR11680:SF12KEGG:00260+2.1.2.1
KEGG:00460+2.1.2.1KEGG:00630+2.1.2.1KEGG:00670+2.1.2.1KEGG:00680+2.1.2.1
ncoils:CoilPfam:PF00464scanprosite:PS00096tair10-symbols:SHM2
unipathway:UPA00193unipathway:UPA00288
Coordinates (TAIR10) chr5:+:9418299..9421725
Molecular Weight (calculated) 59133.30 Da
IEP (calculated) 9.10
GRAVY (calculated) -0.26
Length 533 amino acids
Sequence (TAIR10)
(BLAST)
001: MALALRRLSS SVKKPISLLS SNGGSLRFMS SLSTAAMAES EKSRSSWIKQ LNASLDEIDP EVADIIELEK ARQWKGFELI PSENFTSLSV MQAVGSVMTN
101: KYSEGYPGAR YYGGNEYIDM AETLCQKRAL EAFQLDPSKW GVNVQSLSGS PANFQVYTAL LKPHERIMAL DLPHGGHLSH GYQTDTKKIS AVSIFFETMP
201: YRLDENTGYI DYDQLEKSAV LFRPKLIVAG ASAYARLYDY ARIRKVCNKQ KAVMLADMAH ISGLVAAGVI PSPFEYADVV TTTTHKSLRG PRGAMIFFRK
301: GLKEINKQGK EVMYDYEDRI NQAVFPGLQG GPHNHTITGL AVALKQARTP EYKAYQDQVL RNCSKFAELD IRPTVIISYG LSMQTLLAKG YDLVSGGTDN
401: HLVLVNLKNK GIDGSRVEKV LELVHIAANK NTVPGDVSAM VPGGIRMGTP ALTSRGFIEE DFAKVAEYFD LAVKIALKIK AESQGTKLKD FVATMQSNEK
501: LQSEMSKLRE MVEEYAKQFP TIGFEKETMR YKE
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)