AT5G26780.2
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:mitochondrion 1.000 What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : serine hydroxymethyltransferase 2 | ||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes a protein with serine hydroxymethyltransferase activity which is thought to be localized in the mitochondrial matrix. SHM2 expression fails to rescue the conditional lethal phenotype of the shm1-1 mutant, defective in SHM1. | ||||||||||||||||||||||||
Computational Description (TAIR10) |
serine hydroxymethyltransferase 2 (SHM2); FUNCTIONS IN: glycine hydroxymethyltransferase activity, cobalt ion binding, zinc ion binding; INVOLVED IN: glycine metabolic process, L-serine metabolic process; LOCATED IN: mitochondrion, mitochondrial respiratory chain complex I; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine transhydroxymethyltransferase 1 (TAIR:AT4G37930.1); Has 11607 Blast hits to 11584 proteins in 2835 species: Archae - 259; Bacteria - 6404; Metazoa - 333; Fungi - 289; Plants - 321; Viruses - 6; Other Eukaryotes - 3995 (source: NCBI BLink). | ||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr5:+:9418299..9421725 | ||||||||||||||||||||||||
Molecular Weight (calculated) | 59133.30 Da | ||||||||||||||||||||||||
IEP (calculated) | 9.10 | ||||||||||||||||||||||||
GRAVY (calculated) | -0.26 | ||||||||||||||||||||||||
Length | 533 amino acids | ||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MALALRRLSS SVKKPISLLS SNGGSLRFMS SLSTAAMAES EKSRSSWIKQ LNASLDEIDP EVADIIELEK ARQWKGFELI PSENFTSLSV MQAVGSVMTN 101: KYSEGYPGAR YYGGNEYIDM AETLCQKRAL EAFQLDPSKW GVNVQSLSGS PANFQVYTAL LKPHERIMAL DLPHGGHLSH GYQTDTKKIS AVSIFFETMP 201: YRLDENTGYI DYDQLEKSAV LFRPKLIVAG ASAYARLYDY ARIRKVCNKQ KAVMLADMAH ISGLVAAGVI PSPFEYADVV TTTTHKSLRG PRGAMIFFRK 301: GLKEINKQGK EVMYDYEDRI NQAVFPGLQG GPHNHTITGL AVALKQARTP EYKAYQDQVL RNCSKFAELD IRPTVIISYG LSMQTLLAKG YDLVSGGTDN 401: HLVLVNLKNK GIDGSRVEKV LELVHIAANK NTVPGDVSAM VPGGIRMGTP ALTSRGFIEE DFAKVAEYFD LAVKIALKIK AESQGTKLKD FVATMQSNEK 501: LQSEMSKLRE MVEEYAKQFP TIGFEKETMR YKE |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)