AT5G23720.3
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 0.881 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : dual specificity protein phosphatase family protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Encodes a protein tyrosine phosphatase Propyzamide-Hypersensitive 1 (PHS1). One of the mutant alleles, phs1-1, is hypersensitive to the microtubule-destabilizing drug propyzamide, suggesting that PHS1 may be involved in phosphorylation cascades that control the dynamics of cortical microtubules in plant cells. A second allele, phs1-3, is hypersensitive to abscisic acid, indicating a possible involvement of PHS1 in ABA signalling. | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
PROPYZAMIDE-HYPERSENSITIVE 1 (PHS1); FUNCTIONS IN: protein tyrosine/serine/threonine phosphatase activity, phosphoprotein phosphatase activity; INVOLVED IN: cortical microtubule organization, regulation of gene expression, response to abscisic acid stimulus, regulation of stomatal movement; LOCATED IN: cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422), Protein kinase-like domain (InterPro:IPR011009), Protein-tyrosine phosphatase, active site (InterPro:IPR016130), Actin-fragmin kinase, catalytic (InterPro:IPR015275), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340); BEST Arabidopsis thaliana protein match is: dual specificity protein phosphatase 1 (TAIR:AT3G23610.2); Has 3765 Blast hits to 3755 proteins in 331 species: Archae - 11; Bacteria - 94; Metazoa - 2032; Fungi - 332; Plants - 347; Viruses - 172; Other Eukaryotes - 777 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:+:7998506..8002594 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 103126.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.37 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -0.56 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 920 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MVLSQEKDEE KDLYLVHDEH ESPLPLTVTS RVLYMLGDIA SGPAYRFTQW LDLVRKRSAT YGSSGFPHRL HRIDDMVTSA GERNTDPKSP PSRQSSEISL 101: WERLGKASTV DIDSSCFSWN MLSSLHHTEH SSSTDHSEED QSKPLEVTVN SGGVVFFALF NSSSSEDASR KEEAAVIKFA SSRMATQSER LGYEFSKWLG 201: VQIPQARVIH SCNPEWTLIK EATEKAQAKA TSEGDEVGEM TCSELLEALE LSRCLLLMSY VHGCPMLESM SSFETEEKAE RAAAALGRIL VLDLVIRNED 301: RLPCRQLRWR GNPANLLLTD RIVSSAKHHE CSFDEAFDSA IKRYHPKDYR SIQRERRASS VDSRSRLSIS DQMLVSQASD FSDITESPRS YDTGLMSPMS 401: DRSVAADFHL VAIDSGVPRR PPAGKRASDQ EIYPRLVELL LNSSQYSSNL LHEITEGSLG YPQAEDGEET SNVRSVVTPV VREFRNGFRA GLRDLQEFHI 501: FLVTLHQKLD VLLRAFFSMM DKTMCADFDR EDFAVPESPS HTHGHEVNHY PSPSKDRVPS DNSSDHSESD MQKSVPRTPN SENKEDGSSP KSRESWHGRS 601: GKGGESLSSQ RLAAKLRDFH KFAKVDAESN KELDQWNETL RNEVMKLCQE NGFNTGFFEG SDNNSCTDAY ELKVRLEHIL ERISLISKAA NTEKPSMIQE 701: NLFIGGGLAA RSIYTLQHLG ITHVLCLCAN EIGQSDTQYP DLFEYQNFSI TDDEDSNIES IFQEALDFIK HGEETGGKIL VHCFEGRSRS ATVVLAYLML 801: QKKLTLLEAW SKLRKVHRRA QPNDGFARIL INLDKKCHGK VSMEWRQRKP TMKVCPVCGK NAGLSSSSLK LHLQKSHRKL SSGSVDSAMN MEIQKALEAL 901: KLSTGRGSSA SSNSFQSHPG |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)