AT5G23080.2
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : SWAP (Suppressor-of-White-APricot)/surp domain-containing protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Curator Summary (TAIR10) |
Interacts with TATA-box binding protein 2. Contains domains with strong similarity to G-patch and SWAP domains, characteristic of RNA binding and processing proteins. Colocalizes with the splicing regulator SRp34 to subnuclear particles. Role in RNA binding or processing. Mutants display developmental defects, including reduced plant height, polycotyly, and reduced vascularization. Strong genetic interaction between TGH and AMP1. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Computational Description (TAIR10) |
TOUGH (TGH); FUNCTIONS IN: protein binding, RNA binding; INVOLVED IN: multicellular organismal development, phloem or xylem histogenesis, RNA processing; LOCATED IN: nucleus; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1604 (InterPro:IPR011666), SWAP/Surp (InterPro:IPR000061); Has 34900 Blast hits to 18983 proteins in 949 species: Archae - 12; Bacteria - 1329; Metazoa - 18979; Fungi - 3127; Plants - 2236; Viruses - 165; Other Eukaryotes - 9052 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:-:7743226..7748889 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Molecular Weight (calculated) | 101503.00 Da | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| IEP (calculated) | 6.65 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GRAVY (calculated) | -1.11 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Length | 900 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MGSDEEDFVF HGTPIEREEE IASRKKKAVA GASGNLRTLP AWKQEVTDEE GRRRFHGAFT GGYSAGYYNT VGSKEGWAPQ SFTSSRQNRA GARKQSISDF 101: LDEDEKADME GKSLSASSQF DTFGFTAAEH SRKHAEKEQH ERPSAIPGPV PDELVAPVSE SIGVKLLLKM GWRRGHSIKE VRASSDARRE ARKAFLAFYT 201: DENTKETPDS LVSETEVETS LGEDIKISES TPVYVLNPKQ DLHGLGYDPF KHAPEFRGKI APGFGIGALE ELDVEDEDVY AGYDFDQTYV IEDEQPARQS 301: NDNRLRLTSK EHDVLPGFGA AKNSDYSMER FNPPIIPKDF VARHKFSGPL EAETKPTVSA PPEVPPPADN NLKLLIEGFA TFVSRCGKLY EDLSREKNQS 401: NQLFDFLREG NGHDYYARRL WEEQQKRKDQ SKLTLDVKVS PTVQKMTAET RGSLLGEKPL QRSLKETDTS ASSGGSFQFP TNLSDTFTKS ASSQEAADAV 501: KPFKDDPAKQ ERFEQFLKEK YKGGLRTTDS NRVNSMSESA RAQERLDFEA AAEAIEKGKA YKEVRRATEQ PLDFLAGGLQ FTSGGTEQIK DTGVVDMKSS 601: KTYPKREEFQ WRPSPLLCKR FDLPDPFMGK LPPAPRARNK MDSLVFLPDT VKAASARQVS ESQVPKKETS IEEPEVEVEV ENVERPVDLY KAIFSDDSED 701: DEDQPMNGKI QEGQEKKNEA AATTLNRLIA GDFLESLGKE LGFEVPMEEE IKSRSKPEDS SDKRLDRPGL KEKVEEKTSS LTLGSEEEKS RKKREKSPGK 801: RSGGNDLSSS ESSGDERRRK RYNKKDRHRN DSESDSSSDY HSRDKQGSRS RSKRRESSRE KRSSHKKHSK HRRTKKSSSS RYSSDEEQKE SRREKKRRRD |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)