AT5G22220.3
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Subcellular Consensus
(Prediction and Experimental) min:  :max.
SUBAcon:nucleus 1.000 What is SUBAcon? |
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| Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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| Description (TAIR10) | protein_coding : E2F transcription factor 1 | ||||||||||||
| Curator Summary (TAIR10) |
Member of the E2F transcription factors, (cell cycle genes), key components of the cyclin D/retinoblastoma/E2F pathway. Binds DPA and RBR1 proteins. Expressed throughout the cell cycle. Abundance increased by auxin through stabilization of the protein. Elevates CDK levels and activity, even under hormone-free conditions. Promotes cell division and shortens cell doubling time, inhibits cell growth. Transgenic plants overexpressing AtE2Fa contained an increased level of AtE2Fb transcripts that is paralleled by an increase in the amount of the AtE2Fb protein, suggesting that AtE2Fb expression might actually be up-regulated by the AtE2Fa transcription factor. | ||||||||||||
| Computational Description (TAIR10) |
E2F transcription factor 1 (E2F1); CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Transcription factor E2F/dimerisation partner (TDP) (InterPro:IPR003316), E2F Family (InterPro:IPR015633); BEST Arabidopsis thaliana protein match is: E2F transcription factor 3 (TAIR:AT2G36010.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). | ||||||||||||
| Protein Annotations |
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| Coordinates (TAIR10) | chr5:+:7360749..7364120 | ||||||||||||
| Molecular Weight (calculated) | 51463.00 Da | ||||||||||||
| IEP (calculated) | 4.40 | ||||||||||||
| GRAVY (calculated) | -0.67 | ||||||||||||
| Length | 466 amino acids | ||||||||||||
| Sequence (TAIR10) (BLAST) |
001: MSEEVPQQFP SSKRQLHPSL SSMKPPLVAP GEYHRFDAAE TRGGGAVADQ VVSDAIVIKS TLKRKTDLVN QIVEVNELNT GVLQTPVSGK GGKAKKTSRS 101: AKSNKSGTLA SGSNAGSPGN NFAQAGTCRY DSSLGLLTKK FINLIKQAED GILDLNKAAD TLEVQKRRIY DITNVLEGIG LIEKTLKNRI QWKGLDVSKP 201: GETIESIANL QDEVQNLAAE EARLDDQIRE SQERLTSLSE DENNKRLLFV TENDIKNLPC FQNKTLIAVK APHGTTLEVP DPDEAGGYQR RYRIILRSTM 301: GPIDVYLVSQ FEESFEDIPQ ADEPSNVPDE PSNVPDVPSN LPSTSGLPEN HDVSMPMKEE STERNMETQE VDDTQRVYSD IESHDFVDGI MKIVPPDLDM 401: GVDYWFRSEV GEVSITDMWP DEYWNQMITF DQDHAGPSDN KILEQPQTPS SPTPEESTAT RSPTGS |
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| See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)