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AT5G20320.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.994
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : dicer-like 4
Curator
Summary (TAIR10)
Encodes an RNase III-like enzyme that catalyzes processing of trans-acting small interfering RNA precursors in a distinct small RNA biogenesis pathway. The protein is also involved in the production of 21-nt primary siRNAs from both inverted-repeat constructs and endogenous sequences, as well as the RDR6-dependent 21-nt secondary siRNAs involved in long-range cell-to-cell signaling. It binds DRB4, a ds-RNA binding protein.
Computational
Description (TAIR10)
dicer-like 4 (DCL4); CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), Double-stranded RNA-binding (InterPro:IPR001159), Argonaute/Dicer protein, PAZ (InterPro:IPR003100), Ribonuclease III (InterPro:IPR000999), Double-stranded RNA-binding-like (InterPro:IPR014720), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Dicer double-stranded RNA-binding fold (InterPro:IPR005034), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: dicer-like 2 (TAIR:AT3G03300.3).
Protein Annotations
eggNOG:COG0571eggNOG:COG1111eggNOG:KOG0701EMBL:CP002688
EnsemblPlants:AT5G20320EnsemblPlants:AT5G20320.2entrez:832154ExpressionAtlas:F4K482
Gene3D:1.10.1520.10Gene3D:3.30.160.20Gene3D:3.40.50.300GeneID:832154
GO:GO:0003677GO:GO:0003723GO:GO:0004525GO:GO:0005524
GO:GO:0006396Gramene:AT5G20320.2hmmpanther:PTHR14950hmmpanther:PTHR14950:SF15
InterPro:IPR000999InterPro:IPR001650InterPro:IPR003100InterPro:IPR005034
InterPro:IPR006935InterPro:IPR014001InterPro:IPR014720InterPro:IPR027417
KEGG:ath:AT5G20320KO:K11592ncoils:CoilPaxDb:F4K482
Pfam:PF00271Pfam:PF00636Pfam:PF02170Pfam:PF03368
Pfam:PF04851Pfam:PF14709Pfscan:PS50137Pfscan:PS50142
Pfscan:PS50821Pfscan:PS51192Pfscan:PS51194Pfscan:PS51327
PRIDE:F4K482PROSITE:PS00517PROSITE:PS50137PROSITE:PS50142
PROSITE:PS50821PROSITE:PS51192PROSITE:PS51194PROSITE:PS51327
ProteinModelPortal:F4K482Proteomes:UP000006548RefSeq:NP_001190348.1scanprosite:PS00517
SMART:SM00358SMART:SM00487SMART:SM00490SMART:SM00535
SMART:SM00949SMR:F4K482STRING:3702.AT5G20320.1SUPFAM:SSF52540
SUPFAM:SSF54768SUPFAM:SSF69065TAIR:AT5G20320tair10-symbols:DCL4
UniGene:At.31201UniProt:F4K482
Coordinates (TAIR10) chr5:-:6859571..6869068
Molecular Weight (calculated) 189688.00 Da
IEP (calculated) 6.73
GRAVY (calculated) -0.21
Length 1688 amino acids
Sequence (TAIR10)
(BLAST)
0001: MRDEVDLSLT IPSKLLGKRD REQKNCEEEK NKNKKAKKQQ KDPILLHTSA ATHKFLPPPL TMPYSEIGDD LRSLDFDHAD VSSDLHLTSS SSVSSFSSSS
0101: SSLFSAAGTD DPSPKMEKDP RKIARRYQVE LCKKATEENV IVYLGTGCGK THIAVMLIYE LGHLVLSPKK SVCIFLAPTV ALVEQQAKVI ADSVNFKVAI
0201: HCGGKRIVKS HSEWEREIAA NEHCFIKMEC ISLLIFDECH HAQQQSNHPY AEIMKVFYKS ESLQRPRIFG MTASPVVGKG SFQSENLSKS INSLENLLNA
0301: KVYSVESNVQ LDGFVSSPLV KVYYYRSALS DASQSTIRYE NMLEDIKQRC LASLKLLIDT HQTQTLLSMK RLLKRSHDNL IYTLLNLGLW GAIQAAKIQL
0401: NSDHNVQDEP VGKNPKSKIC DTYLSMAAEA LSSGVAKDEN ASDLLSLAAL KEPLFSRKLV QLIKILSVFR LEPHMKCIIF VNRIVTARTL SCILNNLELL
0501: RSWKSDFLVG LSSGLKSMSR RSMETILKRF QSKELNLLVA TKVGEEGLDI QTCCLVIRYD LPETVTSFIQ SRGRARMPQS EYAFLVDSGN EKEMDLIENF
0601: KVNEDRMNLE ITYRSSEETC PRLDEELYKV HETGACISGG SSISLLYKYC SRLPHDEFFQ PKPEFQFKPV DEFGGTICRI TLPANAPISE IESSLLPSTE
0701: AAKKDACLKA VHELHNLGVL NDFLLPDSKD EIEDELSDDE FDFDNIKGEG CSRGDLYEMR VPVLFKQKWD PSTSCVNLHS YYIMFVPHPA DRIYKKFGFF
0801: MKSPLPVEAE TMDIDLHLAH QRSVSVKIFP SGVTEFDNDE IRLAELFQEI ALKVLFERGE LIPDFVPLEL QDSSRTSKST FYLLLPLCLH DGESVISVDW
0901: VTIRNCLSSP IFKTPSVLVE DIFPPSGSHL KLANGCWNID DVKNSLVFTT YSKQFYFVAD ICHGRNGFSP VKESSTKSHV ESIYKLYGVE LKHPAQPLLR
1001: VKPLCHVRNL LHNRMQTNLE PQELDEYFIE IPPELSHLKI KGLSKDIGSS LSLLPSIMHR MENLLVAIEL KHVLSASIPE IAEVSGHRVL EALTTEKCHE
1101: RLSLERLEVL GDAFLKFAVS RHLFLHHDSL DEGELTRRRS NVVNNSNLCR LAIKKNLQVY IRDQALDPTQ FFAFGHPCRV TCDEVASKEV HSLNRDLGIL
1201: ESNTGEIRCS KGHHWLYKKT IADVVEALVG AFLVDSGFKG AVKFLKWIGV NVDFESLQVQ DACIASRRYL PLTTRNNLET LENQLDYKFL HKGLLVQAFI
1301: HPSYNRHGGG CYQRLEFLGD AVLDYLMTSY FFTVFPKLKP GQLTDLRSLS VNNEALANVA VSFSLKRFLF CESIYLHEVI EDYTNFLASS PLASGQSEGP
1401: RCPKVLGDLV ESCLGALFLD CGFNLNHVWT MMLSFLDPVK NLSNLQISPI KELIELCQSY KWDREISATK KDGAFTVELK VTKNGCCLTV SATGRNKREG
1501: TKKAAQLMIT NLKAHENITT SHPLEDVLKN GIRNEAKLIG YNEDPIDVVD LVGLDVENLN ILETFGGNSE RSSSYVIRRG LPQAPSKTED RLPQKAIIKA
1601: GGPSSKTAKS LLHETCVANC WKPPHFECCE EEGPGHLKSF VYKVILEVED APNMTLECYG EARATKKGAA EHAAQAAIWC LKHSGFLC
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)