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AT5G16780.1
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
  • PMID:28865150 (2017): extracellular region plant-type cell wall
  • PMID:24134884 (2013): cytoskeleton microtubules
  • PMID:22550958 (2012): plastid
  • PMID:22522809 (2012): cytosol cytosolic ribosomes
  • PMID:15496452 (2005): nucleus
SUBAcon links
AGI-AGI relationships
Coexpression PPI
Description (TAIR10) protein_coding : SART-1 family
Curator
Summary (TAIR10)
Encodes a protein belonging to SART-1 family. The gene is expressed in the basal region of the developing embryo during heart stage. Phenotypic analyses of dot2 mutants suggest that this protein plays a role in root, shoot, and flower development. dot2 mutants are dwarved plants that display an aberrant spurred leaf venation pattern and fail to flower. In the roots DOT2 appears to be require for normal meristem organization and maintenance and the proper expression of PIN and PLT genes.
Computational
Description (TAIR10)
DEFECTIVELY ORGANIZED TRIBUTARIES 2 (DOT2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: in 9 processes; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: SART-1 protein (InterPro:IPR005011); BEST Arabidopsis thaliana protein match is: SART-1 family (TAIR:AT3G14700.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
Protein Annotations
BioGrid:16817eggNOG:ENOG410XSTTeggNOG:KOG2217EMBL:AF367317
EMBL:AK317581EMBL:AL391147EMBL:CP002688EnsemblPlants:AT5G16780
EnsemblPlants:AT5G16780.1entrez:831541GeneID:831541Genevisible:Q9LFE0
GO:GO:0000387GO:GO:0000481GO:GO:0005634GO:GO:0005730
GO:GO:0009908GO:GO:0009933GO:GO:0010087GO:GO:0010305
GO:GO:0010588GO:GO:0045292GO:GO:0046540GO:GO:0048364
GO:GO:0048366GO:GO:0048367GO:GO:0048528Gramene:AT5G16780.1
hmmpanther:PTHR14152hmmpanther:PTHR14152:SF5HOGENOM:HOG000239098InParanoid:Q9LFE0
IntAct:Q9LFE0InterPro:IPR005011iPTMnet:Q9LFE0KEGG:ath:AT5G16780
KO:K11984ncoils:CoilOMA:KAGQAHFPANTHER:PTHR14152:SF5
PaxDb:Q9LFE0Pfam:PF03343Pfam:Q9LFE0PhylomeDB:Q9LFE0
PIR:T51510PRIDE:Q9LFE0PRO:PR:Q9LFE0ProteinModelPortal:Q9LFE0
Proteomes:UP000006548Reactome:R-ATH-72163RefSeq:NP_197180.1STRING:3702.AT5G16780.1
TAIR:AT5G16780tair10-symbols:DOT2tair10-symbols:MDFUniGene:At.31636
UniProt:Q9LFE0
Coordinates (TAIR10) chr5:-:5517784..5521566
Molecular Weight (calculated) 94147.30 Da
IEP (calculated) 6.14
GRAVY (calculated) -1.42
Length 820 amino acids
Sequence (TAIR10)
(BLAST)
001: MEVEKSKSRH EIREERADYE GSPVREHRDG RRKEKDHRSK DKEKDYDREK IRDKDHRRDK EKERDRKRSR DEDTEKEISR GRDKEREKDK SRDRVKEKDK
101: EKERNRHKDR ENERDNEKEK DKDRARVKER ASKKSHEDDD ETHKAAERYE HSDNRGLNEG GDNVDAASSG KEASALDLQN RILKMREERK KKAEDASDAL
201: SWVARSRKIE EKRNAEKQRA QQLSRIFEEQ DNLNQGENED GEDGEHLSGV KVLHGLEKVV EGGAVILTLK DQSVLTDGDV NNEIDMLENV EIGEQKRRNE
301: AYEAAKKKKG IYDDKFNDDP GAEKKMLPQY DEAATDEGIF LDAKGRFTGE AEKKLEELRK RIQGQTTHTF EDLNSSAKVS SDYFSQEEML KFKKPKKKKQ
401: LRKKDKLDLS MLEAEAVASG LGAEDLGSRK DGRRQAMKEE KERIEYEKRS NAYQEAIAKA DEASRLLRRE QVQPFKRDED ESMVLADDAE DLYKSLEKAR
501: RLALIKKEEA GSGPQAVAHL VASSTNQTTD DNTTTGDETQ ENTVVFTEMG DFVWGLQREN DVRKPESEDV FMEEDVAPKA PVEVKEEHPD GLTEVNDTDM
601: DAAEDSSDTK EITPDENIHE VAVGKGLSGA LKLLKDRGTL KEKVEWGGRN MDKKKSKLVG IVDDDGGKES KDKESKDRFK DIRIERTDEF GRTLTPKEAF
701: RLLSHKFHGK GPGKMKEEKR MKQYQEELKL KQMKNSDTPS QSVQRMREAQ AQLKTPYLVL SGHVKPGQTS DPQSGFATVE KDVPGSLTPM LGDRKVEHFL
801: GIKRKSEPGN SDTPPKRPKP
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)