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AT5G09230.3
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
mitochondrion 1.000
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : sirtuin 2
Curator
Summary (TAIR10)
Encodes SRT2, a member of the SIR2 (sirtuin) family HDAC (histone deacetylase) (SRT1/AT5g55760, SRT2/AT5G09230).
Computational
Description (TAIR10)
sirtuin 2 (SRT2); FUNCTIONS IN: NAD binding, DNA binding, zinc ion binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; INVOLVED IN: chromatin silencing, defense response to bacterium, negative regulation of defense response, regulation of transcription, DNA-dependent; LOCATED IN: chromatin silencing complex, nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent histone deacetylase, silent information regulator Sir2 (InterPro:IPR003000); BEST Arabidopsis thaliana protein match is: sirtuin 1 (TAIR:AT5G55760.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Protein Annotations
EnsemblPlants:AT5G09230EnsemblPlants:AT5G09230.3entrez:830782Gene3D:3.40.50.1220
hmmpanther:PTHR11085hmmpanther:PTHR11085:SF6Pfam:PF02146Pfscan:PS50305
ProteinModelPortal:F4KCI3tair10-symbols:SRT2UniProt:F4KCI3
Coordinates (TAIR10) chr5:+:2871655..2873275
Molecular Weight (calculated) 36480.80 Da
IEP (calculated) 9.44
GRAVY (calculated) -0.45
Length 324 amino acids
Sequence (TAIR10)
(BLAST)
001: MNMRRVFGGV STDLFPSRSM YRPLQSGGNL VMLFKGCRRF VRTTCRVSIP GGSLGNESKA PPRFLRDRKI VPDADPPNME DIHKLYRLFE QSSRLTILTG
101: AGVSTECGIP DYRSPNGAYS SGFKPITHQE FTRSSRARRR YWARSYAGWR RFTAAQPGPA HTALASLEKA GRINFMITQN VDRLHHRAGS DPLELHGTVY
201: TVMCLECGFS FPRDLFQDQL KAINPKWAEA IESIDHGDPG SEKSFGMKQR PDGDIEIDEK FWEEGFHIPV CEKCKGVLKP DVIFFGDNIP KERATQAMEV
301: AKQSDAFLVL GSSLMTMSAF RLCR
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)