AT5G05690.3
Subcellular Consensus
(Prediction and Experimental) min: :max .
SUBAcon:cytosol 0.931 What is SUBAcon? |
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Experimental Localisations and PPI |
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SUBAcon links
AGI-AGI relationships |
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Description (TAIR10) | protein_coding : Cytochrome P450 superfamily protein | ||||||||||||||||||||||||||||||||||||||||||||||||
Curator Summary (TAIR10) |
Encodes a member of the CP90A family, a cytochrome P450 monooxygenase which converts 6-deoxocathasterone to 6-deoxoteasterone in the late C6 oxidation pathway and cathasterone to teasterone in the early C6 oxidation pathway of brassinolide biosynthesis. Expressed in cotyledons and leaves. Mutants display de-etiolation and derepression of light-induced genes in the dark, dwarfism, male sterility and activation of stress-regulated genes in the light. The expression of the gene using a CPD promoter:LUC fusion construct was shown to be under circadian and light control. Additionally, the circadian regulation was shown to be independent of BR levels as it remains unchanged in <i>bri1</i> mutant lines. CPD appears to be involved in the autonomous pathway that regulates the transition to flowering, primarily through a BRI1-mediated signaling pathway that affects FLC expression levels, as uncovered by double mutant analyses. | ||||||||||||||||||||||||||||||||||||||||||||||||
Computational Description (TAIR10) |
CONSTITUTIVE PHOTOMORPHOGENIC DWARF (CPD); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: in 9 processes; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 90, subfamily D, polypeptide 1 (TAIR:AT3G13730.1); Has 33335 Blast hits to 33282 proteins in 1705 species: Archae - 54; Bacteria - 6996; Metazoa - 10729; Fungi - 6001; Plants - 7974; Viruses - 3; Other Eukaryotes - 1578 (source: NCBI BLink). | ||||||||||||||||||||||||||||||||||||||||||||||||
Protein Annotations |
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Coordinates (TAIR10) | chr5:-:1702907..1706348 | ||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Weight (calculated) | 40506.10 Da | ||||||||||||||||||||||||||||||||||||||||||||||||
IEP (calculated) | 9.70 | ||||||||||||||||||||||||||||||||||||||||||||||||
GRAVY (calculated) | -0.18 | ||||||||||||||||||||||||||||||||||||||||||||||||
Length | 353 amino acids | ||||||||||||||||||||||||||||||||||||||||||||||||
Sequence (TAIR10) (BLAST) |
001: MKGSLHKRMH SLTMSFANSS IIKDHLMLDI DRLVRFNLDS WSSRVLLMEE AKKITFELTV KQLMSFDPGE WSESLRKEYL LVIEGFFSLP LPLFSTTYRK 101: AIQARRKVAE ALTVVVMKRR EEEEEGAERK KDMLAALLAA DDGFSDEEIV DFLVALLVAG YETTSTIMTL AVKFLTETPL ALAQLKEEHE KIRAMKSDSY 201: SLEWSDYKSM PFTQCVVNET LRVANIIGGV FRRAMTDVEI KGYKIPKGWK VFSSFRAVHL DPNHFKDART FNPWRWQSNS VTTGPSNVFT PFGGGPRLCP 301: GYELARVALS VFLHRLVTGF SWVPAEQDKL VFFPTTRTQK RYPIFVKRRD FAT |
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See Also |
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Citation
If you find this resource useful please cite one of the following publications:
Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)
Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)