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AT4G38130.2
Subcellular Consensus
(Prediction and Experimental)
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SUBAcon:
nucleus 0.943
What is SUBAcon?
Experimental Localisations and PPI
FP MS/MS PPI
SUBAcon links
AGI-AGI relationships
Coexpression PPI
no PPI data
Description (TAIR10) protein_coding : histone deacetylase 1
Curator
Summary (TAIR10)
Encodes a histone deacetylase that enhances AtERF7-mediated transcriptional repression. Binds SIM3 and ERF7. Expressed in the nucleus in most tissues examined and throughout the life of the plant. Involved in jasmonic acid and ethylene dependent pathogen resistance. The sequence in GenBank has 17 AG dinucleotide repeats missing, which is also missing in Ler shotgun sequence from Cereon. Although it is annotated to be in Columbia, the GB sequence is probably not of Columbia origin. Plays a role in embryogenesis as mutants grown at higher temperatures display abnormalities in the organization of the root and shoot. Plant lines expressing an RNAi construct targeted against HDA19 shows some resistance to agrobacterium-mediated root transformation.
Computational
Description (TAIR10)
histone deacetylase 1 (HD1); CONTAINS InterPro DOMAIN/s: Histone deacetylase (InterPro:IPR003084), Histone deacetylase superfamily (InterPro:IPR000286); BEST Arabidopsis thaliana protein match is: histone deacetylase 6 (TAIR:AT5G63110.1); Has 8759 Blast hits to 8549 proteins in 1452 species: Archae - 219; Bacteria - 3192; Metazoa - 1525; Fungi - 536; Plants - 478; Viruses - 0; Other Eukaryotes - 2809 (source: NCBI BLink).
Protein Annotations
EC:3.5.1.98eggNOG:COG0123eggNOG:KOG1342EMBL:CP002687
EnsemblPlants:AT4G38130EnsemblPlants:AT4G38130.2entrez:829969ExpressionAtlas:A8MSD0
Gene3D:3.40.800.20GeneID:829969GO:GO:0005634GO:GO:0006351
GO:GO:0006355GO:GO:0032041Gramene:AT4G38130.2hmmpanther:PTHR10625
hmmpanther:PTHR10625:SF127HOGENOM:HOG000225180InterPro:IPR000286InterPro:IPR003084
InterPro:IPR023801iPTMnet:A8MSD0KEGG:ath:AT4G38130KO:K06067
PANTHER:PTHR10625PaxDb:A8MSD0Pfam:PF00850PIRSF:PIRSF037913
PRIDE:A8MSD0PRINTS:PR01270PRINTS:PR01271ProteinModelPortal:A8MSD0
Proteomes:UP000006548RefSeq:NP_001078511.1SMR:A8MSD0STRING:3702.AT4G38130.1
SUPFAM:SSF52768TAIR:AT4G38130tair10-symbols:ATHD1tair10-symbols:HD1
tair10-symbols:HDA1tair10-symbols:HDA19tair10-symbols:RPD3AUniGene:At.25069
UniProt:A8MSD0
Coordinates (TAIR10) chr4:-:17896663..17899057
Molecular Weight (calculated) 52783.40 Da
IEP (calculated) 5.24
GRAVY (calculated) -0.51
Length 469 amino acids
Sequence (TAIR10)
(BLAST)
001: MDTGGNSLAS GPDGVKRKVC YFYDPEVGNY YYGQGHPMKP HRIRMTHALL AHYGLLQHMQ VLKPFPARDR DLCRFHADDY VSFLRSITPE TQQDQIRQLK
101: RFNVGEDCPV FDGLYSFCQT YAGGSVGGSV KLNHGLCDIA INWAGGLHHA KKCEASGFCY VNDIVLAILE LLKQHERVLY VDIDIHHGDG VEEAFYATDR
201: VMTVSFHKFG DYFPGTGHIQ DIGYGSGKYY SLNVPLDDGI DDESYHLLFK PIMGKVMEIF RPGAVVLQCG ADSLSGDRLG CFNLSIKGHA ECVKFMRSFN
301: VPLLLLGGGG YTIRNVARCW CYETGVALGV EVEDKMPEHE YYEYFGPDYT LHVAPSNMEN KNSRQMLEEI RNDLLHNLSK LQHAPSVPFQ ERPPDTETPE
401: VDEDQEDGDK RWDPDSDMDV DDDRKPIPSR VKREAVEPDT KDKDGLKGIM ERGKGCEVEV DESGSTKVK
See Also
Citation
If you find this resource useful please cite one of the following publications:

Hooper CM, Castleden I, Tanz SK, Aryamanesh, and Millar, AH (2017) SUBA4: the interactive data analysis centre for Arabidopsis subcellular protein locations Nucleic Acids Res. Jan 4;45(D1):D1064-D1074. doi: 10.1093/nar/gkw1041 (PubMed)

Hooper CM, Tanz SK, Castleden IR, Vacher MA, Small ID, Millar AH (2014) "SUBAcon: a consensus algorithm for unifying the subcellular localization data of the Arabidopsis proteome. Bioinformatics." 1;30(23):3356-64. (Bioinformatics) (PubMed)